Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mauri Keinänen"'
Autor:
Emerik Osterlund, Ari Ristimäki, Soili Kytölä, Teijo Kuopio, Eetu Heervä, Timo Muhonen, Päivi Halonen, Raija Kallio, Leena-Maija Soveri, Jari Sundström, Mauri Keinänen, Annika Ålgars, Raija Ristamäki, Halfdan Sorbye, Per Pfeiffer, Luís Nunes, Tapio Salminen, Annamarja Lamminmäki, Markus J. Mäkinen, Tobias Sjöblom, Helena Isoniemi, Bengt Glimelius, Pia Osterlund
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundKRAS mutations, present in over 40% of metastatic colorectal cancer (mCRC), are negative predictive factors for anti-EGFR therapy. Mutations in KRAS-G12C have a cysteine residue for which drugs have been developed. Published data on this sp
Externí odkaz:
https://doaj.org/article/decb120b6a4a470ea68f4e7d8f7c7d6d
Autor:
Aki Uutela, Emerik Osterlund, Päivi Halonen, Raija Kallio, Annika Ålgars, Tapio Salminen, Annamarja Lamminmäki, Leena-Maija Soveri, Raija Ristamäki, Kaisa Lehtomäki, Hanna Stedt, Eetu Heervä, Timo Muhonen, Juha Kononen, Arno Nordin, Ali Ovissi, Soili Kytölä, Mauri Keinänen, Jari Sundström, Lasse Nieminen, Markus J. Mäkinen, Teijo Kuopio, Ari Ristimäki, Helena Isoniemi, Pia Osterlund
Background Outcomes after metastasectomy for metastatic colorectal cancer (mCRC) vary with RAS and BRAF mutational status, but their effects on resectability and conversion rates have not been extensively studied. Methods This substudy of the prospec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eebc54b4b9dad91d9d71a2bfc7447fa
http://urn.fi/URN:NBN:fi:jyu-202206163431
http://urn.fi/URN:NBN:fi:jyu-202206163431
Autor:
Philip D. Cotter, Karen Denison, Simone Abmayr, Donna M. McDonald-McGinn, Theresa Yang-Feng, Elaine H. Zackai, Michael R. Altherr, Nancy B. Spinner, Mauri Keinänen, Darrell O. Ricke, Kurt Hirschhorn, Mirja Somer, Tracy J. Wright
Publikováno v:
Human Molecular Genetics. 6:317-324
Wolf-Hirschhorn syndrome (WHS) is a multiple malformation syndrome characterised by mental and developmental defects resulting from the absence of a segment of one chromosome 4 short arm (4p16.3). Due to the complex and variable expression of this di
Autor:
Mauri Keinänen, Sakari Knuutila, Anna Slunga-Tallberg, Kari Ylinen, Tapio Kurki, Wael El-Rifai, Katherine W. Klinger, Olavi Ylikorkala
Publikováno v:
Human Genetics. 96:53-57
We studied the origin of nucleated red blood cells (NRBC) in peripheral venous blood samples from 40 pregnant women carrying a male fetus, using a technique that allows direct chromosomal analysis by in situ hybridisation on immunologically and morph
Autor:
Malija Wessman, Anna Slunga-Tallberg, Kari Ylinen, Sakari Knuutila, Mira Vuorinen, A.-M. Björkqvist, Mauri Keinänen
Publikováno v:
Annals of the New York Academy of Sciences. 731:57-66
Our main aim was to evaluate whether maternal whole venous blood could be used for determination of fetal sex, when no enrichment of fetal cells was attempted and when "standard" interphase cytogenetics and PCR analysis were adopted. Altogether 39 pr
Autor:
Katrin Kepp, Ulrika Liljedahl, Pekka Ellonen, Anthony J. Brookes, Ulvi Talas, Pia Osterman, Mauri Keinänen, Maija Parkkonen, Cecilia M. Lindgren, Päivi Lahermo, Aarno Palotie, Kristina Holmberg, Linda Strömqvist, Grethe I. Grenaker Alnæs, Ann-Christine Syvänen, Christer Halldén, Vessela N. Kristensen, Tomas Axelsson, Per-Henrik Groop, Maija Wessman, Jacob Odeberg, Juha Kere, Dan Holmberg, Janna Saarela, Päivi Kiviluoma, Maria Sterner
Publikováno v:
Human mutation. 27(7)
To survey the quality of SNP genotyping, a joint Nordic quality assessment (QA) round was organized between 11 laboratories in the Nordic and Baltic countries. The QA round involved blinded genotyping of 47 DNA samples for 18 or six randomly selected
Autor:
Sanna M. Siitonen, Anne Mäkipernaa, Ritva Karhu, Mauri Keinänen, Marja Lehtinen, Juhani Vilpo, Minna Tanner, Jorma Isola
Publikováno v:
Cancer genetics and cytogenetics. 95(2)
Classical cytogenetic analysis plays an important role in the diagnosis and classification of childhood acute lymphoblastic leukemia (ALL). However, poor in vitro growth of the malignant cells and suboptimal quality of metaphase spreads may sometimes
Publikováno v:
American Journal of Clinical Pathology. 85:602-604
The authors describe a method that allows three staining pro-cedures to be applied to the same mitotic cell, namely Giemsa staining for morphology, immunoperoxidase staining for surface markers, and banding of the chromosomes for karyotype. After cul