Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Maureen Trudeau"'
Autor:
Pam Takhar, Marc Geirnaert, Scott Gavura, Jaclyn Beca, Rebecca E. Mercer, Avram Denburg, Caroline Muñoz, Mina Tadrous, Ambica Parmar, Francois Dionne, Darryl Boehm, Carole Chambers, Erica Craig, Maureen Trudeau, Matthew C. Cheung, Joanne Houlihan, Valerie McDonald, Petros Pechlivanoglou, Marianne Taylor, Eric Wasylenko, Wiesława Dominika Wranik, Kelvin K. W. Chan
Publikováno v:
Current Oncology, Vol 31, Iss 4, Pp 1876-1898 (2024)
Multi-criteria decision analysis (MCDA) is a value assessment tool designed to help support complex decision-making by incorporating multiple factors and perspectives in a transparent, structured approach. We developed an MCDA rating tool, consisting
Externí odkaz:
https://doaj.org/article/8cbdb12baeaa4a1eacebc73b853c3a3f
Autor:
Daniel Moore-Palhares, Archya Dasgupta, Murtuza Saifuddin, Maria Lourdes Anzola Pena, Shopnil Prasla, Ling Ho, Lin Lu, Joseph Kung, Evan McNabb, Lakshmanan Sannachi, Danny Vesprini, Hanbo Chen, Irene Karam, Hany Soliman, Ewa Szumacher, Edward Chow, Sonal Gandhi, Maureen Trudeau, Belinda Curpen, Greg J Stanisz, Michael Kolios, Gregory J Czarnota
Publikováno v:
PLoS Medicine, Vol 21, Iss 5, p e1004408 (2024)
BackgroundPreclinical studies have demonstrated that tumour cell death can be enhanced 10- to 40-fold when radiotherapy is combined with focussed ultrasound-stimulated microbubble (FUS-MB) treatment. The acoustic exposure of microbubbles (intravascul
Externí odkaz:
https://doaj.org/article/aaf3c1e1de2047dca5dfc823e404d12e
Autor:
Amir Moslemi, Laurentius Oscar Osapoetra, Archya Dasgupta, David Alberico, Maureen Trudeau, Sonal Gandhi, Andrea Eisen, Frances Wright, Nicole Look-Hong, Belinda Curpen, Michael C. Kolios, Gregory J. Czarnota
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveNeoadjuvant chemotherapy (NAC) is a key element of treatment for locally advanced breast cancer (LABC). Predicting the response to NAC for patients with Locally Advanced Breast Cancer (LABC) before treatment initiation could be beneficial to
Externí odkaz:
https://doaj.org/article/52a7c670cc744cb59889c1586cc43836
Autor:
Archya Dasgupta, Daniel DiCenzo, Lakshmanan Sannachi, Sonal Gandhi, Rossana C. Pezo, Andrea Eisen, Ellen Warner, Frances C. Wright, Nicole Look-Hong, Ali Sadeghi-Naini, Belinda Curpen, Michael C. Kolios, Maureen Trudeau, Gregory J. Czarnota
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundIn patients with locally advanced breast cancer (LABC) receiving neoadjuvant chemotherapy (NAC), quantitative ultrasound (QUS) radiomics can predict final responses early within 4 of 16-18 weeks of treatment. The current study was planned t
Externí odkaz:
https://doaj.org/article/e3c47ac0e2c74a71b7d223db1bbe8d39
Autor:
Archya Dasgupta, Murtuza Saifuddin, Evan McNabb, Ling Ho, Lin Lu, Danny Vesprini, Irene Karam, Hany Soliman, Edward Chow, Sonal Gandhi, Maureen Trudeau, William Tran, Belinda Curpen, Greg Stanisz, Arjun Sahgal, Michael Kolios, Gregory J. Czarnota
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Preclinical studies have demonstrated focused ultrasound (FUS) stimulated microbubble (MB) rupture leads to the activation of acid sphingomyelinase-ceramide pathway in the endothelial cells. When radiotherapy (RT) is delivered concurrently w
Externí odkaz:
https://doaj.org/article/373933fd5ef14c519a0eed90f55c3366
Autor:
Ambica Parmar, Wei Fang Dai, Francois Dionne, Marc Geirnaert, Avram Denburg, Tarry Ahuja, Jaclyn Beca, Sylvie Bouchard, Carole Chambers, Melissa J. Hunt, Don Husereau, Elena Lungu, Valerie McDonald, Rebecca E. Mercer, Gunita Mitera, Caroline Muñoz, Rohini Naipaul, Stuart Peacock, Tanya Potashnik, Mina Tadrous, Pam Takhar, Marianne Taylor, Maureen Trudeau, Danica Wasney, Scott Gavura, Kelvin K. W. Chan
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 3776-3786 (2023)
The Canadian Real-world Evidence for Value of Cancer Drugs (CanREValue) collaboration developed an MCDA rating tool to assess and prioritize potential post-market real-world evidence (RWE) questions/uncertainties emerging from public drug funding dec
Externí odkaz:
https://doaj.org/article/4fb575f2c14545e7887f622958f92f21
Autor:
Arlene Chan, Manuel Ruiz-Borrego, Gavin Marx, A. Jo Chien, Hope S. Rugo, Adam Brufsky, Michael Thirlwell, Maureen Trudeau, Ron Bose, José A. García-Sáenz, Daniel Egle, Barbara Pistilli, Johanna Wassermann, Kerry A. Cheong, Benjamin Schnappauf, Dieter Semsek, Christian F. Singer, Navid Foruzan, Daniel DiPrimeo, Leanne McCulloch, Sara A. Hurvitz, Carlos H. Barcenas
Publikováno v:
Breast, Vol 67, Iss , Pp 94-101 (2023)
Background: Neratinib is an irreversible pan-HER tyrosine kinase inhibitor approved for HER2-positive early-stage and metastatic breast cancer. Diarrhea is the most frequent side effect and the most common reason for early discontinuation. The phase
Externí odkaz:
https://doaj.org/article/59dce946fa4342e6b9fbbf464f2e5a40
Autor:
Maureen Trudeau, Brent Fraser
Publikováno v:
Current Oncology, Vol 30, Iss 5, Pp 5047-5049 (2023)
CADTH read with interest the commentary published on 16 December 2022, entitled “Access to Neoadjuvant Pertuzumab for HER2 Positive Breast Cancer in Canada: A Dilemma Increasingly Difficult to Explain” [...]
Externí odkaz:
https://doaj.org/article/d6ad7674762541bdb3788f7754f7b501
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4956-4969 (2022)
Background: Approximately 75% of breast cancer (BC) is associated with luminal differentiation expressing endocrine receptors (ER). For ER+ HER2− tumors, adjuvant endocrine therapy (ET) is the cornerstone treatment. Although relapse events steadily
Externí odkaz:
https://doaj.org/article/19d50871fa534dc3958ed5f056155838
Autor:
Wei Fang Dai, Erica Craig, Brent Fraser, Alex Chambers, Helen Mai, M. Bryson Brown, Craig C. Earle, William K. Evans, Marc Geirnaert, Marianne Taylor, Maureen Trudeau, Daniel Sperber, Jaclyn M. Beca, Avram Denburg, Rebecca E. Mercer, Ambica Parmar, Mina Tadrous, Pam Takhar, Kelvin K. W. Chan, on behalf of the CanREValue Collaboration
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 4645-4654 (2021)
The CanREValue Collaboration established the Reassessment & Uptake Working Group to develop a preliminary process to reassess funded cancer drugs in Canada. A simulated exercise was conducted to evaluate the proposed reassessment process using a real
Externí odkaz:
https://doaj.org/article/524acb9fb32b4ff39d6c84874e0c7e30