Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Maureen P. Lynch"'
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20248- (2023)
Breast cancer predominantly metastasizes to the skeleton. Mechanical loading is reliably anabolic in bone, and also inhibits bone metastatic tumor formation and bone loss in vivo. To study the underlying mechanisms, we developed a 3D culture model fo
Externí odkaz:
https://doaj.org/article/f6816697a04e4d2abb333df5d9666feb
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 3, Pp 370-375 (2021)
Duodenal ectopic varices (DEV) are an uncommon etiology of upper gastrointestinal bleeding and are associated with high mortality. Both the diagnosis and management of DEV are challenging. Multiple treatment modalities exist including endoscopic guid
Externí odkaz:
https://doaj.org/article/17dab9c1b13a4f0d89058f04cf72e35b
Autor:
Jennifer C. Coulombe, Zachary K. Mullen, Maureen E. Lynch, Louis S. Stodieck, Virginia L. Ferguson
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101497- (2021)
The current standard approach for analyzing cortical bone structure and trabecular bone microarchitecture from micro-computed tomography (microCT) is through classic parametric (e.g., ANOVA, Student's T-test) and nonparametric (e.g., Mann-Whitney U t
Externí odkaz:
https://doaj.org/article/016269be6538448eb453c2135fbef3e0
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Advanced breast cancer predominantly metastasizes to the skeleton, at which point patient prognosis significantly declines concomitant with bone loss, pain, and heightened fracture risk. Given the skeleton's sensitivity to mechanical signals, increas
Externí odkaz:
https://doaj.org/article/ef2fb52be61f460989256321af7e0880
Autor:
Rebecca Kolp, Maureen P. Lynch, Lawrence R. Zukerberg, Whitfield B. Growdon, Bo R. Rueda, Rachel M. Clark
Publikováno v:
International Journal of Gynecological Pathology. 33:598-606
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common antibody-mediated limbic encephalitis and is associated with underlying ovarian teratoma. Previous studies suggest that expression of NMDAR on teratoma neural tissue init
Publikováno v:
American Journal of Reproductive Immunology. 72:392-402
Problem The anti-inflammatory impact of three polyunsaturated fatty acids (3-PUFA) in endometriosis is incompletely understood. The effect of 3-PUFA on endometriosis-like lesions is evaluated as a potential anti-inflammatory treatment target. Method
Autor:
Senji Shirasawa, Liangjing Wang, Lawrence R. Zukerberg, Manish Gala, Daniel S. Shue, Bo R. Rueda, Thomas R. Austin, Maria Pino, Masayoshi Yamamoto, Daniel C. Chung, Maureen P. Lynch, Hirotoshi Kikuchi
Publikováno v:
International Journal of Cancer. 134:2041-2050
The KRAS oncogene influences angiogenesis, metastasis and chemoresistance in colorectal cancers (CRCs), and these processes are all enhanced in hypoxic conditions. To define functional activities of mutant KRAS in a hypoxic microenvironment, we first
Autor:
Angela Cleary, Junya Zhu, Douglas Brandoff, Kristen G. Schaefer, Jane C. Weeks, Maureen P. Lynch, Sherri O. Stuver, Saul N. Weingart, Susan D. Block, Donna L. Berry
Publikováno v:
Journal of Pain and Symptom Management. 43:1072-1081
Context Pain is common among patients with advanced cancer despite the dissemination of clinical pain care guidelines. Objectives We sought to assess the quality of pain care among patients with advanced disease. Methods We reviewed the records of 85
Publikováno v:
Journal of Hospice & Palliative Nursing. 13:106-111
Autor:
Mari Mino-Kenduson, Hirotoshi Kikuchi, Maureen P. Lynch, Do-Youn Park, Takaaki Imamura, Daniel C. Chung, Ramnik J. Xavier, Yusuke Mizukami, Bo R. Rueda, Yair Benita, Maria-Teresa Herraiz
Publikováno v:
International Journal of Cancer. 124:763-771
Hypoxia-inducible factor (HIF)-1 and HIF-2 are heterodimeric transcription factors that mediate the cellular response to hypoxia. Their key regulatory subunits, HIF-1alpha and HIF-2alpha, are induced similarly by hypoxia, but their functional roles i