Výsledky vyhledávání - "Maureen Mburu"

Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function

Autor: Jianhui Zhu, Rafey Feroze, Jonathan A. Kopechek, Jissy Cyriac, Linda Lavery, Maureen Mburu, Daniel Whitehurst, Charles F. McTiernan, Xucai Chen, Flordeliza S. Villanueva

Publikováno v: Theranostics

MicroRNAs (miRs) are dysregulated in pathological left ventricular hypertrophy. AntimiR inhibition of miR-23a suppressed hypertension-induced cardiac hypertrophy in preclinical models, but clinical translation is limited by a lack of cardiac-targeted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509ffef8218fc911f3a4177b940ae6a3
https://doi.org/10.7150/thno.34895

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Nonhematopoietic Nrf2 Deficiency Worsens Chronic Intravascular Hemolysis but Not Cardiomyopathy in Transgenic Sickle Cell Mice

Autor: Samit Ghosh, Solomon F. Ofori-Acquah, Xucai Chen, Flordeliza S. Villanueva, Maureen Mburu

Publikováno v: Blood. 136:18-18

Background: Cardiopulmonary complications are the leading causes of death in sickle cell disease (SCD). Cardiac complications in SCD include left ventricular (LV) hypertrophy and LV systolic or diastolic dysfunction. In SCD, intravascular hemolysis (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1178eb2e458c862d41e4f693650e940e
https://doi.org/10.1182/blood-2020-142783

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