Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Maureen M Barr"'
Autor:
Frances Blow, Kate Jeffrey, Franklin Wang-Ngai Chow, Inna A. Nikonorova, Maureen M. Barr, Atlanta G. Cook, Bram Prevo, Dhanya K. Cheerambathur, Amy H. Buck
Publikováno v:
Open Biology, Vol 14, Iss 11 (2024)
In the free-living nematode Caenorhabditis elegans, the transmembrane protein SID-2 imports double-stranded RNA into intestinal cells to trigger systemic RNA interference (RNAi), allowing organisms to sense and respond to environmental cues such as t
Externí odkaz:
https://doaj.org/article/18b76df2d4cb4bd18d50b00e8cbcaeb3
Autor:
Jonathon D Walsh, Juan Wang, Molly DeHart, Inna A Nikonorova, Jagan Srinivasan, Maureen M Barr
Publikováno v:
PLoS Genetics, Vol 18, Iss 12, p e1010560 (2022)
The cilium acts as an antenna receiving and sending signals, the latter via extracellular vesicles (EVs). In C. elegans and mammals, the Autosomal Dominant Polycystic Kidney Disease (ADPKD) gene products polycystin-1 (PC1) and polycystin-2 (PC2) loca
Externí odkaz:
https://doaj.org/article/4c305ba884dc44868391692cdd220c41
Autor:
Kade M Power, Jyothi S Akella, Amanda Gu, Jonathon D Walsh, Sebastian Bellotti, Margaret Morash, Winnie Zhang, Yasmin H Ramadan, Nicole Ross, Andy Golden, Harold E Smith, Maureen M Barr, Robert O'Hagan
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009052 (2020)
Ciliary microtubules are subject to post-translational modifications that act as a "Tubulin Code" to regulate motor traffic, binding proteins and stability. In humans, loss of CCP1, a cytosolic carboxypeptidase and tubulin deglutamylating enzyme, cau
Externí odkaz:
https://doaj.org/article/c31953d4b8684ae9b72f982eed9b6462
Autor:
Jyothi S Akella, Stephen P Carter, Ken Nguyen, Sofia Tsiropoulou, Ailis L Moran, Malan Silva, Fatima Rizvi, Breandan N Kennedy, David H Hall, Maureen M Barr, Oliver E Blacque
Publikováno v:
eLife, Vol 9 (2020)
Cilia both receive and send information, the latter in the form of extracellular vesicles (EVs). EVs are nano-communication devices that influence cell, tissue, and organism behavior. Mechanisms driving ciliary EV biogenesis are almost entirely unkno
Externí odkaz:
https://doaj.org/article/255a9f0af14d40348773432bb55495c4
Autor:
Maureen M Barr
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006426 (2016)
Externí odkaz:
https://doaj.org/article/8c5d4acfcf784fbab2742e3f229af9a3
Autor:
Jyothi S. Akella, Maureen M. Barr
Publikováno v:
Dev Neurobiol
Cilia are microtubule-based organelles that display diversity in morphology, ultrastructure, protein composition, and function. The ciliary microtubules of C. elegans sensory neurons exemplify this diversity and provide a paradigm to understand mecha
Publikováno v:
Journal of Neurogenetics. 34:323-334
Sexual dimorphism is a device that supports genetic diversity while providing selective pressure against speciation. This phenomenon is at the core of sexually reproducing organisms. Caenorhabditis elegans provides a unique experimental system where
Publikováno v:
Nature's Gift to Neuroscience ISBN: 9781003239758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb2cafed2e622b135a61c41b2e3aedd
https://doi.org/10.1201/9781003239758-14
https://doi.org/10.1201/9781003239758-14
Autor:
Jyothi S. Akella, Alexander L. Cope, Peter Tilton, Inna A. Nikonorova, Kaiden M. Power, Premal Shah, Jonathon D. Walsh, Maureen M. Barr, Amber R. Krauchunas, Juan Wang
Extracellular vesicle (EV)-based signaling is a challenge to study, due to EV small size, heterogeneity, and limited information on cargo content in vivo. We present Caenorhabditis elegans as a discovery platform that allows single EV tracking from s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90a9dcebd14c174940ca16655736083e
https://doi.org/10.1101/2021.09.23.461577
https://doi.org/10.1101/2021.09.23.461577
Autor:
Natalia S. Morsci, Jyothi S. Akella, Malan Silva, David H. Hall, William J. Rice, Ken C. Q. Nguyen, Maureen M. Barr
Publikováno v:
Biology of the Cell. 111:95-107
Background informationThe current consensus on cilia development posits that the ciliary transition zone (TZ) is formed via extension of nine centrosomal microtubules. In this model, TZ structure remains unchanged in microtubule number throughout the