Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Maureen J O'Sullivan"'
Publikováno v:
Cancer Treatment and Research Communications, Vol 32, Iss , Pp 100584- (2022)
Malignant rhabdoid tumour (MRT) is a rare and aggressive paediatric tumour that typically arises in the kidneys or central nervous system (CNS). The malignancy often affects patients under the age of three and is associated with an extremely poor sur
Externí odkaz:
https://doaj.org/article/5cfd439a23e944f498c50405a08a45a2
Publikováno v:
Cancer Treatment and Research Communications, Vol 32, Iss , Pp 100579- (2022)
Malignant rhabdoid tumour (MRT) is a rare, aggressive paediatric malignancy most commonly diagnosed in those below the age of three. MRTs can arise in soft tissue but are more often associated with the central nervous system or kidney. Unfortunately,
Externí odkaz:
https://doaj.org/article/354788277a24412589ea047937c78c70
Autor:
Masayo Kagami, Maureen J O'Sullivan, Andrew J Green, Yoshiyuki Watabe, Osamu Arisaka, Nobuhide Masawa, Kentarou Matsuoka, Maki Fukami, Keiko Matsubara, Fumiko Kato, Anne C Ferguson-Smith, Tsutomu Ogata
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000992 (2010)
Human chromosome 14q32.2 harbors the germline-derived primary DLK1-MEG3 intergenic differentially methylated region (IG-DMR) and the postfertilization-derived secondary MEG3-DMR, together with multiple imprinted genes. Although previous studies in ca
Externí odkaz:
https://doaj.org/article/d8524d6f7d1d463a9540c008994f13a9
Nonsense mutation in the novel PERCC1 gene as a genetic cause of congenital diarrhea and enteropathy
Autor:
Dina, Marek-Yagel, Emily, Stenke, Ben, Pode-Shakked, Cara, Dunne, Ellen, Crushell, Anthea, Bryce-Smith, Michael, McDermott, Maureen J, O'Sullivan, Alvit, Veber, Mansa, Krishnamurthy, James M, Wells, Yair, Anikster, Billy, Bourke
Publikováno v:
Human Genetics. 142:691-696
Congenital diarrheas and enteropathies (CODEs) constitute a heterogeneous group of individually rare disorders manifesting with infantile-onset chronic diarrhea. Genomic deletions in chromosome 16, encompassing a sequence termed the ‘intestine-crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1bfc06a30c6835917b1a23dd4244ac
https://doi.org/10.1007/s00439-022-02486-1
https://doi.org/10.1007/s00439-022-02486-1
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Purpose Malignant rhabdoid tumour (MRT) is a rare and aggressive childhood malignancy that occurs in the kidneys or central nervous system and is associated with very poor prognosis. Chemoresistance is a major issue in the treatment of this malignanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2433591cc885abf1a8443e079bbf85c8
https://doi.org/10.1007/s00432-023-04734-x
https://doi.org/10.1007/s00432-023-04734-x
Autor:
Cornelius F. Boerkoel, Catherine J. Pallen, Mason Bond, Timothy J. Triche, Samuel Aparicio, Gulisa Turashvili, Maureen J. O'Sullivan, Patrick C.W. Wong, Guobin Sun, Kunho Choi, Nichola Osborne, Miraj Chowdhury, Sheetal A. Mitra, Cheryl Walton, Hok Khim Fam
Supplementary Figures - PDF file 381K, S1. Specificity of the Tdp1 antiserum. S2. Tdp1 expression in pediatric solid tumors. S3. Generation of transient and constitutive TDP1 knockdown by treatment with siRNA and shRNA and assay for sensitivity of Td
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24dbfd6bfb7b765c49e68e90d3c93eb
https://doi.org/10.1158/1541-7786.22509633.v1
https://doi.org/10.1158/1541-7786.22509633.v1
Autor:
Cornelius F. Boerkoel, Catherine J. Pallen, Mason Bond, Timothy J. Triche, Samuel Aparicio, Gulisa Turashvili, Maureen J. O'Sullivan, Patrick C.W. Wong, Guobin Sun, Kunho Choi, Nichola Osborne, Miraj Chowdhury, Sheetal A. Mitra, Cheryl Walton, Hok Khim Fam
Supplementary Tables - PDF file 330K, Supplementary Table 1. Nucleotide sequences for oligonucleotides, TDP1 siRNAs and TDP1 shRNAs used. Supplementary Table 2. Comparison of Tdp1 expression between noncancerous skeletal muscle and RMS subtypes. Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129299397b3c99d98886e8e330400506
https://doi.org/10.1158/1541-7786.22509630
https://doi.org/10.1158/1541-7786.22509630
Autor:
Cornelius F. Boerkoel, Catherine J. Pallen, Mason Bond, Timothy J. Triche, Samuel Aparicio, Gulisa Turashvili, Maureen J. O'Sullivan, Patrick C.W. Wong, Guobin Sun, Kunho Choi, Nichola Osborne, Miraj Chowdhury, Sheetal A. Mitra, Cheryl Walton, Hok Khim Fam
Rhabdomyosarcoma is the most common soft tissue sarcoma in children. Metastatic rhabdomyosarcoma in children has a 5-year event-free survival rate of TDP1 or inhibition of poly(ADP-ribose) polymerase-1 (PARP-1), an enzyme in the same complex as TDP1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3580accf9db3347642bf13a8aaae7bb1
https://doi.org/10.1158/1541-7786.c.6539355
https://doi.org/10.1158/1541-7786.c.6539355
Autor:
Paul S. Meltzer, Lee Helman, Jian-Bing Fan, Joshua D. Schiffman, Katherine A. Janeway, Constantine Stratakis, Karel Pacak, Marina Bibikova, Maureen J. O'Sullivan, Joshua J. Waterfall, Yonghong Wang, Yuelin Zhu, Laura Jones, Zengfeng Wang, Brandy Klotzle, Mark Raffeld, Jerzy Lasota, Robert L. Walker, Eva Szarek, Paraskevi Xekouki, Mona S. Jahromi, William I. Smith, Martha Quezado, Maria Tsokos, Maria Merino, Carly Smith, Markku Miettinen, Su Young Kim, J. Keith Killian
Supplementary Figure 1 - PDF file 1233K, Supplemental Figure 1: Representative array comparative genomic hybridization (aCGH) results of genomic copy number near-normal GIST (left column, n=5) and genomic copy number abnormal GIST (right column, n=5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34911773e60f32682a85666c24a414e
https://doi.org/10.1158/2159-8290.22529759
https://doi.org/10.1158/2159-8290.22529759
Autor:
Cornelius F. Boerkoel, Catherine J. Pallen, Mason Bond, Timothy J. Triche, Samuel Aparicio, Gulisa Turashvili, Maureen J. O'Sullivan, Patrick C.W. Wong, Guobin Sun, Kunho Choi, Nichola Osborne, Miraj Chowdhury, Sheetal A. Mitra, Cheryl Walton, Hok Khim Fam
Supplementary Figure and Table Legends - PDF file 96K, Supplementary Figure and Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3915144bcea3bc5c81a780bbb919d4c5
https://doi.org/10.1158/1541-7786.22509636
https://doi.org/10.1158/1541-7786.22509636