Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Maureen Howard"'
Autor:
Jie Liu, Lijuan Wang, Feifei Zhao, Serena Tseng, Cyndhavi Narayanan, Lei Shura, Stephen Willingham, Maureen Howard, Susan Prohaska, Jens Volkmer, Mark Chao, Irving L Weissman, Ravindra Majeti
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137345 (2015)
CD47 is a widely expressed cell surface protein that functions as a regulator of phagocytosis mediated by cells of the innate immune system, such as macrophages and dendritic cells. CD47 serves as the ligand for a receptor on these innate immune cell
Externí odkaz:
https://doaj.org/article/f1cca79d01244eb9845a30d57782bea8
Autor:
Susan S. Prohaska, Rhonda Aoki, Timothy J. O'Rourke, Sreenivasa R Chandana, Amita Patnaik, Mark P. Chao, Jie Huang, Matthew Axt, Nehal Lakhani, Kyriakos P. Papadopoulos, Muralidhar Beeram, Sukhmani K. Padda, Dana Supan, Heather A. Wakelee, Victor M. Villalobos, Chris H. Takimoto, Jens-Peter Volkmer, George A. Fisher, Irving L. Weissman, Sujata Narayanan, Ravindra Majeti, Branimir I. Sikic, Mark D. Pegram, Balaji Agoram, Sumit A. Shah, A. Dimitrios Colevas, James Y. Chen, Drew W. Rasco, Jie Liu, Maureen Howard
Publikováno v:
J Clin Oncol
PURPOSE To evaluate the safety, pharmacokinetics, and pharmacodynamics of Hu5F9-G4 (5F9), a humanized IgG4 antibody that targets CD47 to enable phagocytosis. PATIENTS AND METHODS Adult patients with solid tumors were treated in four cohorts: part A,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582789961410d3b42881be3bad76c3f0
https://europepmc.org/articles/PMC7186585/
https://europepmc.org/articles/PMC7186585/
Autor:
Nakul Singhal, Jack Ansell, Maureen Howard, Kelly Rudd, Jason Gilleylen, Peter A. Kouides, Alex C. Spyropoulos, Darren M. Triller, Anna Viscusi
Publikováno v:
Annals of Pharmacotherapy. 49:113-124
Background: Oral anticoagulants are prescribed to millions of Americans, and consequently are among the medications most likely to contribute to emergency department visits and hospitalizations. Although guidelines and consensus statements promote sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e83d1c53dc2cc2eb00d2ce92d2899f5
https://doi.org/10.1177/1060028014555176
https://doi.org/10.1177/1060028014555176
Publikováno v:
Scandinavian Journal of Immunology. 6:1317-1322
B-lymphocyte colony-forming cells and various B-lymphocyte developmental states were examined for expression of surface immunoglobulin. B-lymphocyte colony-forming-cells appeared to possess a significantly greater amount of surface immunoglobulin tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1f6eb783f2401e88b71b1ddd7a097d
https://doi.org/10.1111/j.1365-3083.1977.tb00371.x
https://doi.org/10.1111/j.1365-3083.1977.tb00371.x
Autor:
Jens Peter Volkmer, Lei Shura, Lijuan Wang, Mark P. Chao, Jie Liu, Stephen B. Willingham, Maureen Howard, Irving L. Weissman, Susan S. Prohaska, Feifei Zhao, Serena Tseng, Ravindra Majeti, Cyndhavi Narayanan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0137345 (2015)
PLoS ONE, Vol 10, Iss 9, p e0137345 (2015)
CD47 is a widely expressed cell surface protein that functions as a regulator of phagocytosis mediated by cells of the innate immune system, such as macrophages and dendritic cells. CD47 serves as the ligand for a receptor on these innate immune cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd92bdb49884eadd3c0e8a6c38a2d1a
https://pubmed.ncbi.nlm.nih.gov/26390038
https://pubmed.ncbi.nlm.nih.gov/26390038
Autor:
Robert D. Berahovich, Brian E. Mcmaster, Calvin J. Kuo, Anita Melikian, Dan R. Littman, Kim Wright, Bretton C. Summers, Thomas J. Schall, Jennifer M. Burns, Mark E. T. Penfold, Maureen Howard, Mary Jean Sunshine, Yu Wang, Kevin Wei, Zhenhua Miao
Publikováno v:
The Journal of Experimental Medicine
The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12 [CXCL12]) regulates many essential biological processes, including cardiac and neuronal development, stem cell motility, neovascularization, angiogenesis, apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508930a6b1010a099c09516f487076ba
https://doi.org/10.1084/jem.20052144
https://doi.org/10.1084/jem.20052144
Publikováno v:
The Journal of Immunology. 174:7341-7351
Although chemokines CCL3/MIP-1α and CCL5/RANTES are considered to be primary CCR1 ligands in inflammatory responses, alternative CCR1 ligands have also been described. Indeed, four such chemokines, CCL6/C10/MIP-related protein-1, CCL9/MIP-1γ/MIP-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c30db314df39d126cfdc17731dacc46
https://doi.org/10.4049/jimmunol.174.11.7341
https://doi.org/10.4049/jimmunol.174.11.7341
Autor:
Allen G. Harmsen, Maureen Howard, Simon Monard, Santiago Partida-Sanchez, Debra A. Cockayne, Stephen Goodrich, Elaine L. Jacobson, Troy D. Randall, Kim Kusser, Frances E. Lund, Norman J. Oppenheimer, Beth A. Garvy
Publikováno v:
Nature Medicine. 7:1209-1216
Cyclic ADP-ribose is believed to be an important calcium-mobilizing second messenger in invertebrate, mammalian and plant cells. CD38, the best-characterized mammalian ADP-ribosyl cyclase, is postulated to be an important source of cyclic ADP-ribose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c38be7b8d31265294e01654ac277b05
https://doi.org/10.1038/nm1101-1209
https://doi.org/10.1038/nm1101-1209
Publikováno v:
Current Opinion in Immunology. 12:725-730
Many autoantigens have been identified in human patients and in rodent models. In numerous experimental settings, these autoantigens or related autoreactive lymphocytes can transfer autoimmunity. Although autoreactivity spreads to new epitopes during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77724f4c3902e5f32e246f1f67ca232
https://doi.org/10.1016/s0952-7915(00)00169-2
https://doi.org/10.1016/s0952-7915(00)00169-2
Autor:
Emma Lees, Eric Lam, Daniel Mahony, Wei Wei Wu, Yong Jun Liu, Piotr Sicinski, Janet Glassford, Maureen Howard, Gerry G. B. Klaus, Nanette Solvason, Robert A. Weinberg, David A.D. Parry
Publikováno v:
International Immunology. 12:631-638
Progression into G(1) in B lymphocytes is regulated by cyclins D2 and D3, components of the cell cycle machinery currently believed to have overlapping and potentially redundant roles in cell cycle control. To study the specific role of cyclin D2 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd33997c73608739396d308b62ad0b72
https://doi.org/10.1093/intimm/12.5.631
https://doi.org/10.1093/intimm/12.5.631