Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maureen Hargaden"'
Publikováno v:
Journal of Medical Primatology. 52:64-78
The cynomolgus macaque has become the most used non-human primate species in nonclinical safety assessment during the past decades.This review summarizes the biological data and organ system development milestones of the cynomolgus macaque available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205702db5132060e4a73a9518be47081
https://doi.org/10.1111/jmp.12622
https://doi.org/10.1111/jmp.12622
Autor:
J Paciorek, Bolin, Jessica D. Ventre, P Gardiner, D Lavelle, L Calzetta, Shahid Tannu, Alexandra Hicks, Nadine Tare, Maureen Hargaden, A Morschauser, Laura Singer, Ta Lin, ID Knowles, M Cazzola, H Michel, Maria Gabriella Matera, Louis M. Renzetti
Publikováno v:
British Journal of Pharmacology. 161:1329-1342
BACKGROUND AND PURPOSE Vasoactive intestinal peptide is expressed in the respiratory tract and induces its effects via its receptors, VPAC1 and VPAC2. RO5024118 is a selective VPAC2 receptor agonist derived via chemical modification of an earlier VPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c952eb6f6347bd34e1f060d95271ebc
https://doi.org/10.1111/j.1476-5381.2010.00975.x
https://doi.org/10.1111/j.1476-5381.2010.00975.x
Autor:
Tina Molinaro, Robert Alan Goodnow, Louis M. Renzetti, Alexandra Hicks, Satish Choudhry, Xin Wei, Gesine J. Hermann, Qi Qiao, Anjula Pamidimukkala, A. Robert Catala, Maureen Hargaden, Jian Ping Lou, Nadine Tare, John O’Neil, Ueli Gubler, Karen Pozzani, David J Moore, Jennifer Santiago, Ruben Marcano, Paul Gillespie, Rachid Hamid, Noal Cohen, Hyesun Oh, Lisa C. F. Chao, Laura Singer, Jefferson Wright Tilley, Romyr Dominique, Grazyna Kurylko, Ying L. Li, Radhika Venkat, Achyutharao Sidduri, Matthew Blake Wright, Ann F. Hoffman, Shahid Tannu, Gary Cavallo, Nader Fotouhi, Thomas Egan, Martin Lamb, Jessica D. Ventre, Agnieszka Kowalczyk, D Lavelle, Helena Mancebo
Publikováno v:
Journal of Medicinal Chemistry. 53:3502-3516
The inhibition of LTB(4) binding to and activation of G-protein-coupled receptors BLT1 and BLT2 is the premise of a treatment for several inflammatory diseases. In a lead optimization effort starting with the leukotriene B(4) (LTB(4)) receptor antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f954d2982302b35c7516d54421fb833
https://doi.org/10.1021/jm1001919
https://doi.org/10.1021/jm1001919
Autor:
Maureen Hargaden, Michael Breton, Stuart H. Goldberg, C. M. Lang, James W. Griffith, Denise Cunningham
Publikováno v:
Ophthalmic Plastic & Reconstructive Surgery. 12:264-272
The goal of the study was to determine, using a nonhuman primate (NHP) model, the minimum duration of elevated intraocular pressure (IOP) (induced by an inflated catheter) necessary to produce significant visual system deficits. In Old World monkeys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7250a2187283086d58f120d3fa384c27
https://doi.org/10.1097/00002341-199612000-00009
https://doi.org/10.1097/00002341-199612000-00009
Autor:
Maureen Hargaden, Laura Singer
Publisher Summary This chapter discusses the external anatomy, musculoskeletal system, and behavior of the guinea pigs. The domestic guinea pig is a descendant of the wild cavy (Cavia aperea), which is a common rodent in South America. It is a nonbur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7f1f7bc740313f3f5f36f6f0a79314d
https://doi.org/10.1016/b978-0-12-380920-9.00020-1
https://doi.org/10.1016/b978-0-12-380920-9.00020-1
Autor:
Leanne C. Alworth, James E. Artwohl, Margaret Batchelder, Beth A. Bauer, Valerie K. Bergdall, Diana M.P. Berger, Cynthia L. Besch-Williford, Thea Brabb, David W. Brammer, Jeleen A. Briscoe, Kristie Brock, Marilyn J. Brown, Rochelle Buffenstein, Andrew Burich, Tanya H. Burkholder, Holly N. Burr, Amy Cassano, Neil D. Christensen, Kimberly Cohen, Lesley A. Colby, Dale M. Cooper, Marcelo A. Couto, Suzanne Craig, Joseph F. Curlee, Erin K. Daugherity, David DeLong, M. Susan DeVries, Robert C. Dysko, William P. Feeney, Stephen A. Felt, Judy Fenyk-Melody, Craig S. Frisk, Ronald F. Di Giacomo, Diane Gaertner, Mihai Gagea-Iurascu, Laura Gallaugher, Tracy L. Gluckman, Fady I. Guirguis, F. Claire Hankenson, Martha Hanes, Maureen Hargaden, Stephen B. Harvey, Susan Henwood, Robert F. Hoyt, Charlie C. Hsu, Richard B. Huneke, Hussein I. Hussein, Rony Kalman, Brian Karolewski, Angela B. Keffer, Lynn S. Keller, Debra Kirchner, Galila Lazarovici, Theresa M. Lee, Vanessa K. Lee, Patrick A. Lester, Stephen I. Levin, Garry Linton, Neil S. Lipman, John P. Long, Megan M. Mahoney, Brent J. Martin, Lisa Martin, James O. Marx, Kirk J. Maurer, Thomas W. Mayer, Nancy L. Merrill, Rashida M. Moore, Kathleen A. Murray, Daniel D. Myers, Katherine A. Naff, Denise Newsom, John N. Norton, Lee-Ronn Paluch, Thomas Park, Cynthia A. Pekow, Xuwen Peng, Stacy Pritt, Robert H. Quinn, Skye Rasmussen, Randall P. Reynolds, Gordon S. Roble, Gaye Ruble, Howard G. Rush, Mary Ball Sauer, Jodi A. Carlson Scholz, Heather Sedlacek, Eleazar Shafrir, Katherine A. Shuster, Jerald Silverman, Laura Singer, Bhupinder Singh, Kathleen Smiler, Gerald D. Smith, Peter C. Smith, Joanne Sohn, Harold F. Stills, Douglas K. Taylor, Peggy T. Tinkey, Rajesh K. Uthamanthil, Helen Valentine, Gerald Van Hoosier, Ida M. Washington, Steven H. Weisbroth, Cheri L. West, Wanda L. West, Bruce H. Williams, Jolaine M. Wilson, Steven R. Wilson, Felix R. Wolf, Richard Young, Ehud Ziv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eefe6cdd45d124f879305320712d9d4b
https://doi.org/10.1016/b978-0-12-380920-9.00060-2
https://doi.org/10.1016/b978-0-12-380920-9.00060-2
Autor:
Anjula Pamidimukkala, Jian Ping Lou, Paul Gillespie, Rachid Hamid, Hyesun Oh, Thomas H. March, D Lavelle, Lisa C. F. Chao, Tina Molinaro, Matthew Blake Wright, Martin Brovarney, A. Robert Catala, John O’Neil, Agnieszka Kowalczyk, Louis M. Renzetti, Nader Fotouhi, Maureen Hargaden, John Satjawatcharaphong, Karen Pozzani, Xin Wei, Thomas Egan, Radhika Venkat, Ruben Marcano, Shahid Tannu, Karim Dabbagh, Helena Mancebo, Laura Singer, Martin Lamb, David J Moore, Jessica D. Ventre, Janet M. Benson, Ying L. Li, Jennifer Santiago, Ann F. Hoffman, Alexandra Hicks, Gary Cavallo, Jose M. Lora, Robert Alan Goodnow, Ueli Gubler, Romyr Dominique, Achyutharao Sidduri, Nadine Tare, Qi Qiao, Grazyna Kurylko
Publikováno v:
Prostaglandinsother lipid mediators. 92(1-4)
Asthma, chronic obstructive pulmonary disease (COPD) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS) are characterized by neutrophilic inflammation and elevated levels of leukotriene B4 (LTB4). However, the exact role of LTB4 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a72bd708fcaa8a3eadcb8c1fcef6fbe
https://pubmed.ncbi.nlm.nih.gov/20214997
https://pubmed.ncbi.nlm.nih.gov/20214997
Publikováno v:
Contemporary topics in laboratory animal science. 44(2)
Newly constructed animal facilities require microbiological evaluation prior to occupation to ensure that all facets of the design not only function accordingly and that the building is ready for introduction of new, healthy animal species and person
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16cd167438a9acec126b08ea49153923
https://pubmed.ncbi.nlm.nih.gov/15773769
https://pubmed.ncbi.nlm.nih.gov/15773769
Publikováno v:
Contemporary topics in laboratory animal science. 42(6)
During the past decade, important advances have been made in the humane care and use of laboratory animals used in toxicology studies, and there is strong international interest by the pharmaceutical sector in continuing with this progress. Because o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7a9c7adefe78854c18c8001c890a4bd
https://pubmed.ncbi.nlm.nih.gov/14615954
https://pubmed.ncbi.nlm.nih.gov/14615954