Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Maureen Gallant"'
Autor:
Naamah L. Zitomersky, Melanie Demers, Kimberly Martinod, Maureen Gallant, Stephen M. Cifuni, Amlan Biswas, Scott Snapper, Denisa D. Wagner
Publikováno v:
TH Open, Vol 01, Iss 01, Pp e11-e23 (2017)
Abstract Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity. The pathogenesis of IBD and its increased thrombotic ri
Externí odkaz:
https://doaj.org/article/1e6e535840484e56b37779e2fa51735a
Autor:
Hideki Hayashi, Deya Cherpokova, Kimberly Martinod, Thilo Witsch, Siu Ling Wong, Maureen Gallant, Stephen M Cifuni, Leonard P Guarente, Denisa D Wagner
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188341 (2017)
Inflammation is a common denominator in chronic diseases of aging. Yet, how inflammation fuels these diseases remains unknown. Neutrophils are the primary leukocytes involved in the early phase of innate immunity and inflammation. As part of their an
Externí odkaz:
https://doaj.org/article/b3dadcf09d9243c48abef0bcbf1dc29f
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
Objective. Measuring NKG2C+CD57+ natural killer (NK) cell expansion to investigate NK responses against human cytomegalovirus (HCMV) and assessing relationships with adaptive immunity against HCMV. Methods. Expansion of NKG2C+CD57+ NK was measured in
Externí odkaz:
https://doaj.org/article/a4c82c3414f24ea790cd2029898c7c12
Autor:
Mahdis Monajemi, Claire F Woodworth, Katrin Zipperlen, Maureen Gallant, Michael D Grant, Mani Larijani
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93428 (2014)
Due to constitutive expression in cells targeted by human immunodeficiency virus (HIV), and immediate mode of viral restriction upon HIV entry into the host cell, APOBEC3G (A3G) and APOBEC3F (A3F) have been considered primarily as agents of innate im
Externí odkaz:
https://doaj.org/article/f7d377f606264b15884137f88a126b5b
Autor:
Maximilian Mauler, Kimberly Martinod, Denisa D. Wagner, Alexander Savchenko, Luise Erpenbeck, Maureen Gallant, Stephen M. Cifuni, Hideki Hayashi, Deya Cherpokova, Thilo Witsch
Publikováno v:
The Journal of Experimental Medicine
Peptidylarginine deiminase 4 (PAD4) citrullinates proteins. In neutrophils, it causes chromatin decondensation and release of NETs, which are injurious. Martinod et al. show in this study that NETs promote fibrosis in a cardiac model and that PAD4-de
Autor:
Maureen Gallant, Kimberly Martinod, Thilo Witsch, Kalamo Farley, Eileen Remold-O'Donnell, Denisa D. Wagner
Publikováno v:
Journal of Thrombosis and Haemostasis. 14:551-558
UNLABELLED ESSENTIALS: Neutrophil elastase (NE) plays a role in extracellular trap formation (NETosis) triggered by microbes. The contribution of NE was evaluated in mouse NETosis models of sterile inflammation and thrombosis. NE is not required for
Autor:
Melanie Demers, Luise Erpenbeck, S. Ananth Karumanchi, Stephen M. Cifuni, Zsuzsanna K. Zsengellér, Maureen Gallant, Isaac E. Stillman, Denisa D. Wagner
Publikováno v:
Journal of the American Society of Nephrology. 27:120-131
Thrombotic microangiopathy (TMA) is a life-threatening condition that affects some, but not all, recipients of vascular endothelial growth factor (VEGF) inhibitors given as part of chemotherapy. TMA is also a complication of preeclampsia, a disease c
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Antiretroviral therapy (ART) effectively extends the life expectancy of human immunodeficiency virus (HIV)-infected individuals; however, age-related morbidities have emerged as major clinical concerns. In this context, coinfection with cytomegalovir
Autor:
Maureen Gallant, Stephen M. Cifuni, Scott B. Snapper, Melanie Demers, Kimberly Martinod, Denisa D. Wagner, Naamah L. Zitomersky, Amlan Biswas
Publikováno v:
TH Open, Vol 01, Iss 01, Pp e11-e23 (2017)
Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity. The pathogenesis of IBD and its increased thrombotic risk is not c
Autor:
Denisa D. Wagner, Christophe Dubois, Soraya Mezouar, Grace M. Thomas, Alexander Brill, Maureen Gallant, Lydie Crescence
Publikováno v:
Journal of Thrombosis and Haemostasis. 13:1310-1319
SummaryBackground The risk of thrombotic complications such as deep vein thrombosis (DVT) during tumor development is well known. Tumors release into the circulation procoagulant microparticles (MPs) that can participate in thrombus formation followi