Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Maureen E. Mork"'
Autor:
Gabriel del Carmen, Laura Reyes-Uribe, Daniel Goyco, Kyera Evans, Charles M. Bowen, Jennifer L. Kinnison, Valerie O. Sepeda, Diane M. Weber, Julie Moskowitz, Maureen E. Mork, Selvi Thirumurthi, Patrick M. Lynch, Miguel A. Rodriguez-Bigas, Melissa W. Taggart, Y. Nancy You, Eduardo Vilar
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveLynch Syndrome (LS) carriers have a significantly increased risk of developing colorectal cancer (CRC) during their lifetimes. Further stratification of this patient population may help in identifying additional risk factors that predispose
Externí odkaz:
https://doaj.org/article/f5b17bbf15784d4dbbd400cc8d3e166e
Autor:
Eduardo Vilar, Y. Nancy You, Patrick M. Lynch, Melissa W. Taggart, Miguel A. Rodriguez-Bigas, Maureen E. Mork, Sarah A. Bannon, Jennifer L. Bosch, Amanda Cuddy, Mala Pande, Kyle Chang, Ester Borras
Supplementary Figure S2. A. Proportion of VUS with different pathogenic probabilities estimated from a calibrated algorithm based on customized MAPP and Polyphen2 scores; B. Proportion of VUS per gene with different pathogenic probabilities; C. Distr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2c5df89cb52c47fbf27c6fa4062131
https://doi.org/10.1158/1940-6207.22534768.v1
https://doi.org/10.1158/1940-6207.22534768.v1
Autor:
Florencia McAllister, Eduardo Vilar, David R. Fogelman, Andrew Futreal, Lei Feng, Matthew H. Katz, Anirban Maitra, Gauri R. Varadhachary, Merve Hasanov, Ester Borras, Maureen E. Mork, Wenli Dong, Jennifer B. Goldstein, Maria F. Montiel, Sarah A. Bannon
Supplementary Table 1. Criteria for Referral of PDAC patients Supplementary Table 2. Comparison patients tested and non-tested patients in the HRC. Supplementary Table 3. Mutation nomenclature and classification Supplementary Table 4. NCCN guidelines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35be832d45d698aa37b07025f487f5ba
https://doi.org/10.1158/1940-6207.22534385.v1
https://doi.org/10.1158/1940-6207.22534385.v1
Autor:
Eduardo Vilar, Y. Nancy You, Patrick M. Lynch, Melissa W. Taggart, Miguel A. Rodriguez-Bigas, Maureen E. Mork, Sarah A. Bannon, Jennifer L. Bosch, Amanda Cuddy, Mala Pande, Kyle Chang, Ester Borras
S1. Variants of unknown significance detected in the MD Anderson cohort. S2. Clinical characteristics of the VUS carriers reported in Supplementary Table 1. Pathogenic mutations detected in the same patient carrying a VUS are presented in bold. S3. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28eae93783f67e21ebdd0f8cf3009f25
https://doi.org/10.1158/1940-6207.22534762
https://doi.org/10.1158/1940-6207.22534762
Autor:
Florencia McAllister, Eduardo Vilar, David R. Fogelman, Andrew Futreal, Lei Feng, Matthew H. Katz, Anirban Maitra, Gauri R. Varadhachary, Merve Hasanov, Ester Borras, Maureen E. Mork, Wenli Dong, Jennifer B. Goldstein, Maria F. Montiel, Sarah A. Bannon
Introduction: We aimed to determine the prevalence and landscape of germline mutations among patients with young-onset pancreatic ductal adenocarcinoma (PDAC) as well as their influence in prognosis.Methods: Patients from two cohorts were studied, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0dce950ea1d41f5f4630391cc30deae
https://doi.org/10.1158/1940-6207.c.6547481.v1
https://doi.org/10.1158/1940-6207.c.6547481.v1
Autor:
Eduardo Vilar, Y. Nancy You, Scott Kopetz, Paul Scheet, Ji Wu, Melissa W. Taggart, Miguel Rodriguez-Bigas, Patrick M. Lynch, Sarah A. Bannon, Maureen E. Mork, Amanda Cuddy, Gita Masand, Ester Borras, William Wu, Jennifer B. Goldstein
Purpose: Determination of microsatellite instability (MSI) by PCR is the gold standard; however, IHC of mismatch repair (MMR) proteins is frequently performed instead. The reliability of these methods on postneoadjuvant therapy specimens is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b71ff91adce1a57f4296d0ddde19a7d
https://doi.org/10.1158/1078-0432.c.6526556.v1
https://doi.org/10.1158/1078-0432.c.6526556.v1
Autor:
Eduardo Vilar, Y. Nancy You, Scott Kopetz, Paul Scheet, Ji Wu, Melissa W. Taggart, Miguel Rodriguez-Bigas, Patrick M. Lynch, Sarah A. Bannon, Maureen E. Mork, Amanda Cuddy, Gita Masand, Ester Borras, William Wu, Jennifer B. Goldstein
Supplementary Figure Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005b1e67b3b3f0c7cc0269e7427dce90
https://doi.org/10.1158/1078-0432.22467170.v1
https://doi.org/10.1158/1078-0432.22467170.v1
Autor:
Eduardo Vilar, Y. Nancy You, Scott Kopetz, Paul Scheet, Ji Wu, Melissa W. Taggart, Miguel Rodriguez-Bigas, Patrick M. Lynch, Sarah A. Bannon, Maureen E. Mork, Amanda Cuddy, Gita Masand, Ester Borras, William Wu, Jennifer B. Goldstein
Supplementary Table 1. Patient Demographic Characteristics. *2 patients with metachronous tumors, 1 poor and 1 moderate; **One patient with both pre- and posttreatment IHC and MSI testing. Supplementary Table 2. Tumor characteristics and results of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4002e8c67be0141bf502fe0310ae7804
https://doi.org/10.1158/1078-0432.22467167
https://doi.org/10.1158/1078-0432.22467167
Autor:
Y. Nancy You, Julie B. Moskowitz, George J. Chang, Maureen E. Mork, Miguel A. Rodriguez-Bigas, Brian K. Bednarski, Craig A. Messick, Matthew M. Tillman, John M. Skibber, Sa T. Nguyen, Scott Kopetz, Eduardo Vilar
Publikováno v:
Diseases of the Colon & Rectum. 66:531-542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4a91841364e8fac5324b218eae84eb
https://doi.org/10.1097/dcr.0000000000002347
https://doi.org/10.1097/dcr.0000000000002347
Autor:
Spring, Holter, Michael J, Hall, Heather, Hampel, Kory, Jasperson, Sonia S, Kupfer, Joy, Larsen Haidle, Maureen E, Mork, Selvi, Palaniapppan, Leigha, Senter, Elena M, Stoffel, Scott M, Weissman, Matthew B, Yurgelun
Publikováno v:
Journal of Genetic Counseling. 31:568-583
Identifying individuals who have Lynch syndrome involves a complex diagnostic workup that includes taking a detailed family history and a combination of various tests such as immunohistochemistry and/or molecular which may be germline and/or somatic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8f26e1a8f604cefbec098382fafc14
https://doi.org/10.1002/jgc4.1546
https://doi.org/10.1002/jgc4.1546