Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maureen E. Estevez"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66480 (2013)
Intrinsically photosensitive retinal ganglion cells (iprgcs) are depolarized by light by two mechanisms: directly, through activation of their photopigment melanopsin; and indirectly through synaptic circuits driven by rods and cones. To learn more a
Externí odkaz:
https://doaj.org/article/6d9dfa18999143749b089e737bad7753
Autor:
Andrew D. Huberman, Onkar S. Dhande, Phong L. Nguyen, Lauren E. Quattrochi, Rana N. El-Danaf, David M. Berson, Maureen E. Estevez
Publikováno v:
The Journal of Neuroscience. 33:17797-17813
When the head rotates, the image of the visual world slips across the retina. A dedicated set of retinal ganglion cells (RGCs) and brainstem visual nuclei termed the “accessory optic system” (AOS) generate slip-compensating eye movements that sta
Autor:
Bart G. Borghuis, Marissa C. Ilardi, Shi-Jun Weng, Patricia M. Fogerson, Maureen E. Estevez, Jonathan B. Demb, O. N. Auferkorte, David M. Berson, E. Chan
Publikováno v:
The Journal of Neuroscience. 32:13608-13620
The photopigment melanopsin confers photosensitivity upon a minority of retinal output neurons. These intrinsically photosensitive retinal ganglion cells (ipRGCs) are more diverse than once believed, comprising five morphologically distinct types, M1
Publikováno v:
Anatomical Sciences Education. 3:309-317
Three-dimensional (3-D) visualization of neuroanatomy can be challenging for medical students. This knowledge is essential in order for students to correlate cross-sectional neuroanatomy and whole brain specimens within neuroscience curricula and to
Autor:
Alexander V. Kolesnikov, M. Carter Cornwall, Rosalie K. Crouch, Maureen E. Estevez, Petri Ala-Laurila, Victor I. Govardovskii
Publikováno v:
The Journal of General Physiology
Cone photoreceptors of the vertebrate retina terminate their response to light much faster than rod photoreceptors. However, the molecular mechanisms underlying this rapid response termination in cones are poorly understood. The experiments presented
Publikováno v:
Nature neuroscience
Summary Daytime vision is mediated by retinal cones which, unlike rods, remain functional even in bright light and dark-adapt rapidly. These cone properties are enabled by rapid regeneration of their pigment. This in turn requires rapid chromophore r
Autor:
Clint L. Makino, Sarah L. McCabe, Maureen E. Estevez, Quanhua He, Peter D. Calvert, Dmitriy Alexeev, Anita L. Zimmerman, M. Carter Cornwall, David E. Ong
Publikováno v:
The Journal of General Physiology
In vertebrate rods, photoisomerization of the 11-cis retinal chromophore of rhodopsin to the all-trans conformation initiates a biochemical cascade that closes cGMP-gated channels and hyperpolarizes the cell. All-trans retinal is reduced to retinol a
Publikováno v:
The Journal of General Physiology
Our ability to see in bright light depends critically on the rapid rate at which cone photoreceptors detect and adapt to changes in illumination. This is achieved, in part, by their rapid response termination. In this study, we investigate the hypoth
Autor:
Vladimir J. Kefalov, King Wai Yau, Massahiro Kono, Maureen E. Estevez, Rosalie K. Crouch, M. Carter Cornwall, Patrice W. Goletz
Publikováno v:
Neuron. 46(6):879-890
Retinal rod and cone pigments consist of an apoprotein, opsin, covalently linked to a chromophore, 11-cis retinal. Here we demonstrate that the formation of the covalent bond between opsin and 11-cis retinal is reversible in darkness in amphibian red
Autor:
Jin-Shan Wang, Maureen E. Estevez, Vladimir J. Kefalov, Susan Q. Shen, Soile Nymark, Joseph C. Corbo, Rikard Frederiksen, M. C. Cornwall
Efficient regeneration of visual pigment following its destruction by light is critical for the function of mammalian photoreceptors. Here, we show that misexpression of a subset of cone genes in therd7mouse hybrid rods enables them to access the nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6af16957450a95425f8c23768139d5
https://europepmc.org/articles/PMC4138333/
https://europepmc.org/articles/PMC4138333/