Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maureen C. Ferran"'
Publikováno v:
Biophysical Reports, Vol 3, Iss 3, Pp 100121- (2023)
The HIV-1 protease is one of several common key targets of combination drug therapies for human immunodeficiency virus infection and acquired immunodeficiency syndrome. During the progression of the disease, some individual patients acquire drug resi
Externí odkaz:
https://doaj.org/article/75f18863473b49f590dcb10a044da419
Publikováno v:
Biophysical Reports, Vol 2, Iss 2, Pp 100056- (2022)
The identification of viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a molecular dynamics (MD)-based approach that goes beyond contact mapping, scales we
Externí odkaz:
https://doaj.org/article/ac62d06856c947a99c5f9f04666b03c9
Autor:
Matthew C Morris, Thomas M Russell, Cole A Lyman, Wesley K Wong, Gordon Broderick, Maureen C Ferran
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263065 (2022)
The matrix (M) protein of vesicular stomatitis virus (VSV) has a complex role in infection and immune evasion, particularly with respect to suppression of Type I interferon (IFN). Viral strains bearing the wild-type (wt) M protein are able to suppres
Externí odkaz:
https://doaj.org/article/f82f83caeb1b4c8ab7a86d4a9690afcf
Autor:
Gregory A. Babbitt, Madhusudan Rajendran, Miranda L. Lynch, Richmond Asare-Bediako, Leora T. Mouli, Cameron J. Ryan, Harsh Srivastava, Kavya Phadke, Makayla L. Reed, Nadia Moore, Maureen C. Ferran, Ernest P. Fokoue
Comparative methods in molecular biology and evolution rely almost entirely upon the analysis of DNA sequence and protein structure, both static forms of information. However, it is widely accepted that protein function results from dynamic machine-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b5ee78403b10edbbb8a53d3cd107dab
https://doi.org/10.1101/2023.04.20.537698
https://doi.org/10.1101/2023.04.20.537698
Autor:
David B. Kushner, Troy D. Cline, Pranav Danthi, Kari M. Debbink, Maureen C. Ferran, Michelle Flenniken, Dylan M. Johnson, Andrew Mehle, Daniel A. Morales, Suchetana Mukhopadhyay, John S. L. Parker, Chelsey C. Spriggs, Lauren A. O’Donnell, Melissa S. Maginnis
Publikováno v:
J Virol
Curriculum guidelines for virology are needed to best guide student learning due to the continuous and ever-increasing volume of virology information, the need to ensure that undergraduate and graduate students have a foundational understanding of ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1b682cc0136e77b7eb9a627900f8d9
https://pubmed.ncbi.nlm.nih.gov/36094313
https://pubmed.ncbi.nlm.nih.gov/36094313
Autor:
Madhusudan Rajendran, Maureen C. Ferran, Leora Mouli, Eric Everingham, Gregory A. Babbitt, Miranda L. Lynch
The HIV-1 protease is one of several common key targets of combination drug therapies for human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS). During the progression of the disease, some individual patients acquir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db9aca79a21416fead8eba3023ac75ae
https://doi.org/10.1101/2022.11.22.517502
https://doi.org/10.1101/2022.11.22.517502
Autor:
Nicholas C. Schug, Joseph P. Hornak, Maureen C. Ferran, Chelsea Weidman, Kelsea G. Jones, Yin Peng Lee, Henry D. Ophardt, Sean Aronow, Emily R. Mahoney, Taylor M. Barrett, Damien E. Dobson, Hans F. Schmitthenner, Stephanie A. Beach, Irene M. Evans, Amy E. Becker, Lauren E. Heese, Ceyda Durmaz, Osarhuwense Otasowie
Publikováno v:
ACS Appl Bio Mater
A practical, modular synthesis of targeted molecular imaging agents (TMIAs) containing near-infrared dyes for optical molecular imaging (OMI) or chelated metals for magnetic resonance imaging (MRI) and single-photon emission correlation tomography or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d434340e36f0174c8eff5e122112b505
https://doi.org/10.1021/acsabm.1c00157
https://doi.org/10.1021/acsabm.1c00157
Publikováno v:
Biophysical reports. 2(2)
The identification of viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a molecular dynamics (MD)-based approach that goes beyond contact mapping, scales we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a254db3406dbe8320ad8ad1e8773be80
https://pubmed.ncbi.nlm.nih.gov/35403093
https://pubmed.ncbi.nlm.nih.gov/35403093
The identification of viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a molecular dynamics (MD) based approach that scales well to a desktop computer with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1a267fc34f0d246d113590b90eb1128
https://doi.org/10.1101/2021.12.06.471374
https://doi.org/10.1101/2021.12.06.471374
Autor:
Alaa A. Abdelmageed, Maureen C. Ferran
Publikováno v:
Curr Protoc Microbiol
Vesicular stomatitis virus (VSV) is the prototypical member of the Rhabdoviridae family of negative-sense single-stranded RNA viruses. This virus has been used as a powerful model system for decades and is currently being used as a vaccine platform a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d5840357ff7b41e700e5bc7cddfe31
https://doi.org/10.1002/cpmc.110
https://doi.org/10.1002/cpmc.110