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Autor:
Maureen Bilinga Tendwa, Lorna Chebon-Bore, Kevin Lobb, Thommas Mutemi Musyoka, Özlem Tastan Bishop
Publikováno v:
Molecules, Vol 26, Iss 10, p 2929 (2021)
The dimeric dihydropyrimidine dehydrogenase (DPD), metalloenzyme, an adjunct anti-cancer drug target, contains highly specialized 4 × Fe2+4S2−4 clusters per chain. These clusters facilitate the catalysis of the rate-limiting step in the pyrimidine
Externí odkaz:
https://doaj.org/article/90bf68471259464a95ff524bd767d516
