Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maureen A May"'
Autor:
Rajesh Narendran, Divya Tumuluru, Maureen A May, Kodavali V Chowdari, Michael L Himes, Kelli Fasenmyer, W Gordon Frankle, Vishwajit L Nimgaonkar
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157867 (2016)
Basic investigations link a Val158Met polymorphism (rs4680) in the catechol-O-methyltransferase (COMT) gene to not only its enzymatic activity, but also to its dopaminergic tone in the prefrontal cortex. Previous PET studies have documented the relat
Externí odkaz:
https://doaj.org/article/1a6966435b4d463cb167f0c55effba60
Evidence of Olfactory Deficits as Part of the Phenotypic Spectrum of Nonsyndromic Orofacial Clefting
Autor:
Carla A. Sanchez, Seth M. Weinberg, Mary L. Marazita, Maureen Anne May, Frederic W.-B. Deleyiannis
Publikováno v:
Journal of Craniofacial Surgery. 26:84-86
Improved understanding of the phenotypic spectrum associated with nonsyndromic orofacial clefting (OFC) has the potential to inform efforts to uncover the etiology of this complex trait. Prior studies report that individuals with OFC are characterize
Autor:
Divya Tumuluru, W. Gordon Frankle, Kelli Fasenmyer, Rajesh Narendran, Kodavali V. Chowdari, Vishwajit L. Nimgaonkar, Maureen A. May, Michael L. Himes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0157867 (2016)
PLoS ONE, Vol 11, Iss 6, p e0157867 (2016)
Basic investigations link a Val158Met polymorphism (rs4680) in the catechol-O-methyltransferase (COMT) gene to not only its enzymatic activity, but also to its dopaminergic tone in the prefrontal cortex. Previous PET studies have documented the relat
Autor:
Chi-Min Chen, Brian J. Lopresti, Rajesh Narendran, Diana Martinez, W. Gordon Frankle, Michael L. Himes, N.S. Mason, Julie C. Price, Chester A. Mathis, Maureen A. May
Publikováno v:
Synapse. 65:1344-1349
Positron emission tomography (PET) studies performed with [(11) C]raclopride have consistently reported lower binding to D(2/3) receptors and lower amphetamine-induced dopamine (DA) release in cocaine abusers relative to healthy controls. A limitatio
Autor:
Rajesh Narendran, W. Gordon Frankle, Chi-Min Chen, Maureen A. May, N. Scott Mason, Khanum Ridler, Marc Laruelle, Chester A. Mathis, Eugenii A. Rabiner, Steve Kendro
Publikováno v:
Synapse. 65:35-40
In a recent PET study, we demonstrated the ability to measure amphetamine-induced DA release in the human cortex with the relatively high affinity dopamine D2/3 radioligand [11C]FLB 457 (Narendran et al., [2009] Synapse 63:447–461). The aim of this
Autor:
Michael L. Himes, Brian J. Lopresti, Chester A. Mathis, Rajesh Narendran, Maureen A. May, Diana Martinez, Julie C. Price, N.S. Mason, W. Gordon Frankle, Dennis C. Daley
Publikováno v:
The American journal of psychiatry. 169(1)
Positron emission tomography (PET) imaging studies in cocaine abusers have shown that low dopamine release in the striatum following an amphetamine challenge is associated with higher relapse rates. One possible mechanism that might lead to lower amp
Autor:
Rajesh, Narendran, N Scott, Mason, Maureen A, May, Chi-Min, Chen, Steve, Kendro, Khanum, Ridler, Eugenii A, Rabiner, Marc, Laruelle, Chester A, Mathis, W Gordon, Frankle
Publikováno v:
Synapse (New York, N.Y.). 65(1)
In a recent PET study, we demonstrated the ability to measure amphetamine-induced DA release in the human cortex with the relatively high affinity dopamine D₂/₃ radioligand [¹¹C]FLB 457 (Narendran et al., [2009] Synapse 63:447-461). The aim of
Autor:
Brian J. Lopresti, Charles M. Laymon, Chester A. Mathis, Natalie D. Velasquez, Rajesh Narendran, Maureen A. May, W. Gordon Frankle, N. Scott Mason, Steve Kendro, Diana Martinez
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 333(2)
(-)-N-Propyl-norapomorphine (NPA) is a full dopamine D(2/3) receptor agonist, and [(11)C]NPA is a suitable radiotracer to image D(2/3) receptors configured in a state of high affinity for agonists with positron emission tomography (PET). In this stud
Autor:
Marc Laruelle, Maureen A. May, N. Scott Mason, Steve Kendro, Khanum Ridler, Eugenii A. Rabiner, Rajesh Narendran, Chi-Min Chen, W. Gordon Frankle, Chester A. Mathis
Publikováno v:
NeuroImage. 52:S40
Publikováno v:
Clinical Pharmacology and Therapeutics. 32:407-417
The average number of self-originated new chemical entities (NCEs) first tested in man by 39 United States-owned pharmaceutical firms in the 3-year period from 1977 to 1979 was 26 a year, approximately half the number investigated annually in the pre