Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes

Autor: Jie Ping, Guochong Jia, Qiuyin Cai, Xingyi Guo, Ran Tao, Christine Ambrosone, Dezheng Huo, Stefan Ambs, Mollie E. Barnard, Yu Chen, Montserrat Garcia-Closas, Jian Gu, Jennifer J. Hu, Esther M. John, Christopher I. Li, Katherine Nathanson, Barbara Nemesure, Olufunmilayo I. Olopade, Tuya Pal, Michael F. Press, Maureen Sanderson, Dale P. Sandler, Toshio Yoshimatsu, Prisca O. Adejumo, Thomas Ahearn, Abenaa M. Brewster, Anselm J. M. Hennis, Timothy Makumbi, Paul Ndom, Katie M. O’Brien, Andrew F. Olshan, Mojisola M. Oluwasanu, Sonya Reid, Song Yao, Ebonee N. Butler, Maosheng Huang, Atara Ntekim, Bingshan Li, Melissa A. Troester, Julie R. Palmer, Christopher A. Haiman, Jirong Long, Wei Zheng

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)

Abstract African-ancestry (AA) participants are underrepresented in genetics research. Here, we conducted a transcriptome-wide association study (TWAS) in AA female participants to identify putative breast cancer susceptibility genes. We built geneti

Externí odkaz: https://doaj.org/article/b9834eb3a0344dc2a7b7b629b0f35afc

Factors influencing intent to receive COVID-19 vaccination among Black and White adults in the southeastern United States, October – December 2020

Autor: Jennifer Cunningham-Erves, Carol S. Mayer, Xijing Han, Landon Fike, Chang Yu, Phyllis M. Tousey, David G. Schlundt, Deepak K. Gupta, Michael T. Mumma, David Walkley, Mark D. Steinwandel, Kathryn M. Edwards, Loren Lipworth, Maureen Sanderson, Xiao-Ou Shu, Martha J. Shrubsole

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 17, Iss 12, Pp 4761-4798 (2021)

Vaccination intent is foundational for effective COVID-19 vaccine campaigns. To understand factors and attitudes influencing COVID-19 vaccination intent in Black and White adults in the US south, we conducted a mixed-methods cross-sectional survey of

Externí odkaz: https://doaj.org/article/3f9c6c183f8d4f68ba65450ed537b3ac

Polygenic hazard score is associated with prostate cancer in multi-ethnic populations

Autor: Minh-Phuong Huynh-Le, Chun Chieh Fan, Roshan Karunamuni, Wesley K. Thompson, Maria Elena Martinez, Rosalind A. Eeles, Zsofia Kote-Jarai, Kenneth Muir, Johanna Schleutker, Nora Pashayan, Jyotsna Batra, Henrik Grönberg, David E. Neal, Jenny L. Donovan, Freddie C. Hamdy, Richard M. Martin, Sune F. Nielsen, Børge G. Nordestgaard, Fredrik Wiklund, Catherine M. Tangen, Graham G. Giles, Alicja Wolk, Demetrius Albanes, Ruth C. Travis, William J. Blot, Wei Zheng, Maureen Sanderson, Janet L. Stanford, Lorelei A. Mucci, Catharine M. L. West, Adam S. Kibel, Olivier Cussenot, Sonja I. Berndt, Stella Koutros, Karina Dalsgaard Sørensen, Cezary Cybulski, Eli Marie Grindedal, Florence Menegaux, Kay-Tee Khaw, Jong Y. Park, Sue A. Ingles, Christiane Maier, Robert J. Hamilton, Stephen N. Thibodeau, Barry S. Rosenstein, Yong-Jie Lu, Stephen Watya, Ana Vega, Manolis Kogevinas, Kathryn L. Penney, Chad Huff, Manuel R. Teixeira, Luc Multigner, Robin J. Leach, Lisa Cannon-Albright, Hermann Brenner, Esther M. John, Radka Kaneva, Christopher J. Logothetis, Susan L. Neuhausen, Kim De Ruyck, Hardev Pandha, Azad Razack, Lisa F. Newcomb, Jay H. Fowke, Marija Gamulin, Nawaid Usmani, Frank Claessens, Manuela Gago-Dominguez, Paul A. Townsend, William S. Bush, Monique J. Roobol, Marie-Élise Parent, Jennifer J. Hu, Ian G. Mills, Ole A. Andreassen, Anders M. Dale, Tyler M. Seibert, UKGPCS collaborators, APCB (Australian Prostate Cancer BioResource), NC-LA PCaP Investigators, The IMPACT Study Steering Committee and Collaborators, Canary PASS Investigators, The Profile Study Steering Committee, The PRACTICAL Consortium

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

A polygenic hazard score (PHS1) improves prostate cancer screening accuracy in European patients. Here, the authors test the performance of a version compatible with OncoArray genotypes (PHS2) in a multi-ethnic dataset and find that it risk-stratifie

Externí odkaz: https://doaj.org/article/2acc58dd13bb4c07abb40966fce96b6f

Disruption of medical care among individuals in the southeastern United States during the COVID-19 pandemic

Autor: Bin Ni, Erin Gettler, Rebecca Stern, Heather M. Munro, Mark Steinwandel, Melinda C. Aldrich, Debra L. Friedman, Maureen Sanderson, David Schlundt, David M. Aronoff, Deepak K. Gupta, Martha J. Shrubsole, Loren Lipworth

Publikováno v: Journal of Public Health Research (2021)

Background: Widespread disruptions of medical care to mitigate COVID-19 spread and reduce burden on healthcare systems may have deleterious public health consequences. Design and Methods: To examine factors contributing to healthcare interruptions du

Externí odkaz: https://doaj.org/article/13a0254bf9634065a0675a73a32423ba

Black Women’s Perspectives on Breast Cancer Risk Assessment

Autor: Lucy B. Spalluto, Kemberlee Bonnet, Chiamaka Sonubi, Sonya A. Reid, Jennifer A. Lewis, Laura L. Ernst, Katie M. Davis, Rifat Wahab, Pooja Agrawal, Chloe D’Agostino, Kris Gregory, Elizabeth Berardi, Crissy Hartsfield, Maureen Sanderson, Rebecca Selove, David Schlundt, Carolyn M. Audet

Publikováno v: Journal of the American College of Radiology. 20:314-323

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2f98d2af2188d4f15561630bbf03317
https://doi.org/10.1016/j.jacr.2023.01.003