Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maura Knapp"'
Autor:
Tu Nguyen, Mei Zheng, Maura Knapp, Nikola Sladojevic, Qin Zhang, Lizhuo Ai, Devin Harrison, Anna Chen, Albert Sitikov, Le Shen, Frank J. Gonzalez, Qiong Zhao, Yun Fang, James J. K. Liao, Rongxue Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Hypoxia-inducible factors (HIFs) are the master regulators of angiogenesis, a process that is impaired in patients with diabetes mellitus (DM). The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT, also known as HIF1β) has b
Externí odkaz:
https://doaj.org/article/3e6f607e61a844fab519c5f2fd1fb7e0
Autor:
Albert Sitikov, Rongxue Wu, Qin Zhang, Lizhuo Ai, Tu Nguyen, James J. K. Liao, Anna Chen, Qiong Zhao, Yun Fang, Devin L. Harrison, Nikola Sladojevic, Maura Knapp, Mei Zheng, Le Shen, Frank J. Gonzalez
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Hypoxia-inducible factors (HIFs) are the master regulators of angiogenesis, a process that is impaired in patients with diabetes mellitus (DM). The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT, also known as HIF1β) has b
Autor:
Maura Knapp, Qin Zhang, Lizhuo Ai, Albert Sitikov, Lifeng Liu, Cristian E Betancourt, Willard W. Sharp, James K. Liao, Rongxue Wu
Publikováno v:
Circulation Research. 127
Introduction: Impaired endothelial function leads to the progression of heart failure after Ischemia-reperfusion (IR). Kinin activation of bradykinin receptor 1 (B1R), a G protein-coupled receptor that has been found to induce capillary leakage, may
Publikováno v:
Acta Pharmacologica Sinica. 40:1-8
Diabetes mellitus is currently a major public health problem. A common complication of diabetes is cardiac dysfunction, which is recognized as a microvascular disease that leads to morbidity and mortality in diabetic patients. While ischemic events a
Autor:
Maura Knapp, Mei Zheng, Alik Stikov, Nikola Sladojevic, Anna Chen, Konstantin G Birukov, Qiong Zhao, Amit Patel, James K Liao, Rongxue Wu
Publikováno v:
Circulation. 138
Introduction: Cardiac microvascular hyperpermeability is a key contributor to heart disease in patients with diabetes. Although the link between diabetes and microvascular barrier dysfunction is largely unknown, expression of the transcription factor
Autor:
James K. Liao, Konstantin G Birukov, Nikola Sladojevic, Anna Cheng, Jorge Andrade, Rongxue Wu, Qiong Zhao, Maura Knapp, Mei Zheng
Publikováno v:
Circulation Research. 123
Background: Increased microvascular permeability and cardiac interstitial edema formation are major contributors to progressive myocyte dysfunction during ischemia/reperfusion (IR) injury. Effective clinical therapies for IR injury are lacking, prima
Autor:
Jyothi Janardanan, Toru Shimizu, Maura Knapp, Nikhil Narang, James K. Liao, John E.A. Blair, Phetcharat Chen, Brian Yu
Publikováno v:
JCI Insight. 2
Although left ventricular (LV) diastolic dysfunction is often associated with hypertension, little is known regarding its underlying pathophysiological mechanism. Here, we show that the actin cytoskeletal regulator, Rho-associated coiled-coil contain
Autor:
Maura Knapp, Mei Zheng, Nikola Sladojevic, Qiong Zhao, Konstaintin G Birukov, James K Liao, Rongxue Wu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: Diabetes leads to endothelial barrier dysfunction and altered endothelial permeability, which results in increased cardiovascular risk. ARNT, also known as HIF-1β, a transcription factor that functions as a master regulator of glucose ho
Publikováno v:
Current Trends in Cardiology.
Aryl hydrocarbon receptor nuclear translocator (ARNT), also known as hypoxia-inducible factor-1 beta (HIF-1β), is a transcription factor that functions as a master regulator of glucose homeostasis. We have previously demonstrated that ARNT expressio
Publikováno v:
Circulation Research. 119
Background: Left ventricular hypertrophy (LVH) is an independent risk factor for heart failure and sudden death. In addition, LVH is also a compensatory mechanism that helps the heart cope with pressure overload. Stress is considered one factor that