Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maulik Nitinkumar Gandhi"'
Autor:
Vijayshree B. Avhad, Rajendra L. Harde, Ashwini A. Joshi, Megha Marathe, Malini Bajpai, Satyawan Jadhav, Mahamad Yunnus A. Mahat, Praveen Kumar Gupta, Sanjib Das, Neelima Khairatkar-Joshi, Maulik Nitinkumar Gandhi, Girish S. Gudi, Deepak K. Bhateja, Srinivas Gullapalli, Shelke Dnyaneshwar Eknath, A. P. Thomas
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:3238-3242
We report analogue-based rational design and synthesis of two novel series of polycyclic heteroarenes, pyrrolo[3,2-b]quinolines and pyrido[2,3-b]indoles, tethered to a biaryl system by a methyl-, ethyl- or propyl ether as PDE10A inhibitors. A number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a331b93cdbdc2cec527f194f2a9492
https://doi.org/10.1016/j.bmcl.2014.06.028
https://doi.org/10.1016/j.bmcl.2014.06.028
Autor:
Srinivas Gullapalli, Machender R. Kandadi, Vikas Karande, Dipak Vasantrao Amrutkar, Hemant Kumar, Maulik Nitinkumar Gandhi, Shridhar Narayanan, Sangeetha Gupta
Publikováno v:
Neuropharmacology. 58:1215-1219
Cannabinoid 1 (CB1) receptors have the ability to change conformation between active (R*) and inactive (R) receptor states. Herein, we further characterize these receptor states using series of saturation radioligand binding studies and their differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db3c3ed0fb6f5df3ddcc5d111895aa4
https://doi.org/10.1016/j.neuropharm.2010.03.001
https://doi.org/10.1016/j.neuropharm.2010.03.001
Autor:
Mahesh Y. Pawar, Abhisek Banerjee, Deepak K. Bhateja, Maulik Nitinkumar Gandhi, Neelima Khairatkar-Joshi, Girish S. Gudi, Sandip Damodar Patil, Laxmikant Atmaram Gharat, Praveen Kumar Gupta, Ramachandra Rao Sangana, Malini Bajpai, Srinivas Gullapalli
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(19)
The synthesis and structure-activity relationship studies of a series of compounds from imidazopyridazinone scaffold as PDE7 inhibitors are disclosed. Potent analogs such as compounds 7 (31nM), 8 (27nM), and 9 (12nM) were identified. The PDE selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f44d9d37e1c4d18a032624ef0945ba3
https://pubmed.ncbi.nlm.nih.gov/22944118
https://pubmed.ncbi.nlm.nih.gov/22944118