Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maude Strobino"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Substitution of lysine 27 with methionine in histone H3.3 (H3.3K27M) is a driver mutation of pediatric high-grade gliomas. Here the authors show that H3.3K27M-mediated alterations in H3K27me3 distribution result in ectopic DNA replication and cell cy
Externí odkaz:
https://doaj.org/article/15ff841362f0489ca570360241b3e7f6
Publikováno v:
Genome Research. 30:1740-1751
Histone H3.3 is a replication-independent variant of histone H3 with important roles in development, differentiation, and fertility. Here, we show that loss of H3.3 results in replication defects in Caenorhabditis elegans embryos at elevated temperat
Publikováno v:
Genome Res
Histone H3.3 is a replication-independent variant of histone H3 with important roles in development, differentiation, and fertility. Here, we show that loss of H3.3 results in replication defects in Caenorhabditis elegans embryos at elevated temperat
Substitution of lysine 27 with methionine in histone H3.3 is a recently discovered driver mutation of pediatric high-grade gliomas. Mutant tumor cells show decreased levels and altered distribution of H3K27me3. How these chromatin changes are establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9d5ed2b87747cdd626d21872144b74