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Autor:
Santa-Mariela Olivera-Ugarte, Marilène Bolduc, Marie-Ève Laliberté-Gagné, Léa-Jeanne Blanchette, Caroline Garneau, Maude Fillion, Pierre Savard, Isabelle Dubuc, Louis Flamand, Omar Farnòs, Xingge Xu, Amine Kamen, Mégan Gilbert, Henintsoa Rabezanahary, Martina Scarrone, Christian Couture, Mariana Baz, Denis Leclerc
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 44
A vaccine candidate to SARS-CoV-2 was constructed by coupling the viral receptor binding domain (RBD) to the surface of the papaya mosaic virus (PapMV) nanoparticle (nano) to generate the RBD-PapMV vaccine. Immunization of mice with the coupled RBD-P