Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maude Boisvert"'
Autor:
Brad R Rosenberg, Marion Depla, Catherine A Freije, Denis Gaucher, Sabrina Mazouz, Maude Boisvert, Nathalie Bédard, Julie Bruneau, Charles M Rice, Naglaa H Shoukry
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007290 (2018)
Most individuals exposed to hepatitis C virus (HCV) become persistently infected while a minority spontaneously eliminate the virus. Although early immune events influence infection outcome, the cellular composition, molecular effectors, and timefram
Externí odkaz:
https://doaj.org/article/b465ecfd4e654bf39641f37a32ae4bfe
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006191 (2017)
The dynamics of the memory CD8 T cell receptor (TCR) repertoire upon virus re-exposure and factors governing the selection of TCR clonotypes conferring protective immunity in real life settings are poorly understood. Here, we examined the dynamics an
Externí odkaz:
https://doaj.org/article/9620d3e708e34b93a5500d8cddb66767
Autor:
Julie Bruneau, Naglaa H. Shoukry, Maude Boisvert, Sabrina Mazouz, Omar Khedr, Mohamed S. Abdel-Hakeem
Publikováno v:
The Journal of Immunology. 207:1180-1193
Hepatitis C virus (HCV) infection resolves spontaneously in ∼25% of acutely infected humans where viral clearance is mediated primarily by virus-specific CD8+ T cells. Previous cross-sectional analysis of the CD8+ TCR repertoire targeting two immun
Autor:
Sabrina, Mazouz, Maude, Boisvert, Mohamed S, Abdel-Hakeem, Omar, Khedr, Julie, Bruneau, Naglaa H, Shoukry
Publikováno v:
J Immunol
Hepatitis C virus (HCV) infection resolves spontaneously in approximately 25% of acutely infected humans where viral clearance is mediated primarily by virus specific CD8+ T cells. Previous cross-sectional analysis of the CD8+ T cell receptor (TCR) r
Autor:
Cynthia A. Derdeyn, Eduardo Salinas, Joseph Marcotrigiano, Julie Bruneau, Nathalie Bédard, Naglaa H. Shoukry, Steven E. Bosinger, Matthew J. Evans, Amit A. Upadhyay, Arash Grakoui, Sydney A. Nelson, Maude Boisvert
Publikováno v:
J Clin Invest
Early appearance of neutralizing antibodies during acute hepatitis C virus (HCV) infection is associated with spontaneous viral clearance. However, the longitudinal changes in antigen-specific memory B cell (MBCs) associated with divergent HCV infect
Autor:
Wanrui Zhang, Jean-Pierre Villeneuve, Maude Boisvert, Julie Bruneau, Elizabeth J. Elrod, Nicole F. Bernard, Arash Grakoui, Joseph Marcotrigiano, Naglaa H. Shoukry
Publikováno v:
The Journal of Immunology. 197:4848-4858
Acute hepatitis C virus (HCV) infection culminates in viral persistence in the majority of cases. Abs that recognize the envelope glycoproteins E1 and E2 are generated during the late stages of acute infection, yet their contribution to spontaneous v
Publikováno v:
Can Liver J
The introduction of small molecules targeting viral functions has caused a paradigm shift in hepatitis C virus (HCV) treatment. Administration of these direct-acting antivirals (DAAs) achieves a complete cure in almost all treated patients with short
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 2, p e1006191 (2017)
PLoS Pathogens, Vol 13, Iss 2, p e1006191 (2017)
The dynamics of the memory CD8 T cell receptor (TCR) repertoire upon virus re-exposure and factors governing the selection of TCR clonotypes conferring protective immunity in real life settings are poorly understood. Here, we examined the dynamics an
Autor:
Maude Boisvert, Naglaa H. Shoukry
Publikováno v:
Frontiers in Immunology
The interferon (IFN)-λ family of type III cytokines includes the closely related interleukin (IL)-28A (IFN-λ2), IL-28B (IFN-λ3), and IL-29 (IFN-λ1). They signal through the Janus kinases (JAK)-signal transducers and activators of transcription pa
Autor:
Catherine A. Freije, Nathalie Bédard, Naglaa H. Shoukry, Maude Boisvert, Charles M. Rice, Marion Depla, Brad R. Rosenberg, Denis Gaucher, Sabrina Mazouz, Julie Bruneau
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007290 (2018)
PLoS Pathogens
PLoS Pathogens
Most individuals exposed to hepatitis C virus (HCV) become persistently infected while a minority spontaneously eliminate the virus. Although early immune events influence infection outcome, the cellular composition, molecular effectors, and timefram