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pro vyhledávání: '"Maude Bigras"'
Autor:
Benoit Laffont, Guillaume Dubois, Alan Stokes, Karine Blouin, Maude Bigras, Julius Haruna, Luis-Alexander Rodriguez, Michael Alan Ringenberg, Nawel Ben Abdeljelil, Jamie K. Young, Johanne Pion, Ornella Binazon
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 113
The novel self-amplifying mRNA (SAM) technology for vaccines consists of an engineered replication-deficient alphavirus genome encoding an RNA-dependent RNA polymerase and the gene of the target antigen. To validate the concept, the rabies glycoprote
Autor:
Hue Tran, Tanya Moran, Iohann Boulay, Brad Thompson, Allison Hagerman, Romit Chakrabarty, Robert Tavcar, Audrey Parenteau, Matthew C. Coffey, Sarah Serl, Maude Bigras
Publikováno v:
Investigational new drugs. 31(6)
Numerous pre-clinical and clinical studies on reovirus have generated valuable information which supports the use of this orphan virus as an investigational drug for cancer treatment. Reolysin® (pelareorep) is a clinical formulation of the human Reo