Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Maude, Fransolet"'
A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
Autor:
Damien Detraux, Marino Caruso, Louise Feller, Maude Fransolet, Sébastien Meurant, Julie Mathieu, Thierry Arnould, Patricia Renard
Publikováno v:
eLife, Vol 12 (2023)
Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a pr
Externí odkaz:
https://doaj.org/article/5371a2011e5f40b5bb90b4a3f61502c9
Autor:
Lola Dechêne, Margaux Colin, Catherine Demazy, Maude Fransolet, Ariane Niesten, Thierry Arnould, Didier Serteyn, Marc Dieu, Patricia Renard
Publikováno v:
Stem Cell Reviews and Reports. 19:550-567
Background Osteoarthritis (OA) is a highly prevalent joint degenerative disease for which therapeutic treatments are limited or invasive. Cell therapy based on mesenchymal stem/stromal cells (MSCs) is therefore seen as a promising approach for this d
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Despite a better understanding in head and neck tumors pathogenesis as well as improvements in radiotherapy and surgery, locally advanced head and neck squamous cell carcinoma (HNSCC) remains of poor prognosis. One promising target is the epidermal g
Externí odkaz:
https://doaj.org/article/2d193cc5c11142979673885444c809e4
Autor:
Camille Huart, Maude Fransolet, Catherine Demazy, Benjamin Le Calvé, Stéphane Lucas, Carine Michiels, Anne-Catherine Wéra
Publikováno v:
Cancers; Volume 14; Issue 6; Pages: 1460
Huart, C, Fransolet, M, Demazy, C, Le Calvé, B, Lucas, S, Michiels, C & Wéra, A C 2022, ' Taking Advantage of the Senescence-Promoting Effect of Olaparib after X-ray and Proton Irradiation Using the Senolytic Drug, ABT-263 ', Cancers, vol. 14, no. 6, 1460 . https://doi.org/10.3390/cancers14061460
Cancers, Vol. 14, no.6, p. 1460 (2022)
Huart, C, Fransolet, M, Demazy, C, Le Calvé, B, Lucas, S, Michiels, C & Wéra, A C 2022, ' Taking Advantage of the Senescence-Promoting Effect of Olaparib after X-ray and Proton Irradiation Using the Senolytic Drug, ABT-263 ', Cancers, vol. 14, no. 6, 1460 . https://doi.org/10.3390/cancers14061460
Cancers, Vol. 14, no.6, p. 1460 (2022)
Radiotherapy (RT) is a key component of cancer treatment. Although improvements have been made over the years, radioresistance remains a challenge. For this reason, a better understanding of cell fates in response to RT could improve therapeutic opti
A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
Autor:
Damien Detraux, Marino Caruso, Louise Feller, Maude Fransolet, Sébastien Meurant, Julie Mathieu, Thierry Arnould, Patricia Renard
Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c0e9ec2934b90834fa8853d3f68dbef
https://doi.org/10.1101/2022.03.10.483773
https://doi.org/10.1101/2022.03.10.483773
Autor:
Emilie Bauwens, Tom Parée, Sébastien Meurant, Inès Bouriez, Clotilde Hannart, Anne-Catherine Wéra, Alexis Khelfi, Antoine Fattaccioli, Sophie Burteau, Catherine Demazy, Maude Fransolet, Clémentine De Schutter, Nathalie Martin, Julien Théry, Gauthier Decanter, Nicolas Penel, Marina Bury, Olivier Pluquet, Marjan Garmyn, Florence Debacq-Chainiaux
Publikováno v:
The Journal of investigative dermatology.
Skin is one of the most exposed organs to external stress. Namely, UV rays are the most harmful stress that could induce important damage leading to skin aging and cancers. At the cellular level, senescence is observed in several skin cell types and
Autor:
Tharwat, Mohy El Dine, Ravikumar, Jimmidi, Andrei, Diaconu, Maude, Fransolet, Carine, Michiels, Julien, De Winter, Emilie, Gillon, Anne, Imberty, Tom, Coenye, Stéphane P, Vincent
Publikováno v:
Journal of medicinal chemistry. 64(19)
Autor:
Lionel Leclere, Maude Fransolet, Francois Cote, Pierre Cambier, Thierry Arnould, Pierre Van Cutsem, Carine Michiels
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0115831 (2015)
Cancer is still one of the leading causes of death worldwide, and finding new treatments remains a major challenge. Previous studies showed that modified forms of pectin, a complex polysaccharide present in the primary plant cell wall, possess antica
Externí odkaz:
https://doaj.org/article/2936e8c10111444eaf45978566484b72
Autor:
Marine C. N. M. Blackman, Tania Capeloa, Justin D. Rondeau, Luca X. Zampieri, Zohra Benyahia, Justine A. Van de Velde, Maude Fransolet, Evangelos P. Daskalopoulos, Carine Michiels, Christophe Beauloye, Pierre Sonveaux
Publikováno v:
Cancers; Volume 14; Issue 18; Pages: 4371
Cancers, Vol. 14, no.18, p. 4371 (2022)
Blackman, M C N M, Capeloa, T, Rondeau, J D, Zampieri, L X, Benyahia, Z, Van de Velde, J A, Fransolet, M, Daskalopoulos, E P, Michiels, C, Beauloye, C & Sonveaux, P 2022, ' Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells ', Cancers, vol. 14, no. 18, 4371 . https://doi.org/10.3390/cancers14184371
Cancers, Vol. 14, no.18, p. 4371 (2022)
Blackman, M C N M, Capeloa, T, Rondeau, J D, Zampieri, L X, Benyahia, Z, Van de Velde, J A, Fransolet, M, Daskalopoulos, E P, Michiels, C, Beauloye, C & Sonveaux, P 2022, ' Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells ', Cancers, vol. 14, no. 18, 4371 . https://doi.org/10.3390/cancers14184371
Distant metastases are detrimental for cancer patients, but the increasingly early detection of tumors offers a chance for metastasis prevention. Importantly, cancers do not metastasize randomly: depending on the type of cancer, metastatic progenitor
Autor:
Maude Fransolet, Karim Bouhjar, Florence Debacq-Chainiaux, Noelle Ninane, Céline Warnon, Catherine Lambert de Rouvroit, Antoine Fattaccioli, Géraldine Piel, Yves Poumay, Denis Mottet, Mathilde Verhoyen
Publikováno v:
Aging (Albany NY)
Originally simply reported to be in a stable and irreversible growth arrest in vitro, senescent cells are now clearly associated with normal and pathological ageing in vivo. They are characterized by several biomarkers and changes in gene expression