Inhibitory Activity of Human Immunodeficiency Virus Aspartyl Protease Inhibitors against Encephalitozoon intestinalis Evaluated by Cell Culture-Quantitative PCR Assay

Autor: Claudine Sarfati, Jean Menotti, Bruno Cassinat, Maud Santillana-Hayat, Francis Derouin, Jean-Michel Molina

Publikováno v: Antimicrobial Agents and Chemotherapy. 49:2362-2366

Immune reconstitution might not be the only factor contributing to the low prevalence of microsporidiosis in human immunodeficiency virus (HIV)-infected patients treated with protease inhibitors, as these drugs may exert a direct inhibitory effect ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2cc0f00ebbdf07f6419fe63af72657
https://doi.org/10.1128/aac.49.6.2362-2366.2005

Unexpected synthesis of (trifluoroethyl)pyrimidines from the heterocyclisation of α-trifluoroacetylpropanenitriles

Autor: Maud Santillana-Hayat, Catherine Mirand, Hatice Berber, Mustapha Soufyane

Publikováno v: Tetrahedron Letters. 43:9233-9235

Some 4-trifluoromethyl-2-aminopyrimidines analogous to trimethoprim and 5-trifluoroethyl-2,4-diaminopyrimidines analogous to pyrimethamine were prepared from enamino(trifluoromethyl)ketones and α-trifluoroacetylpropanenitriles, respectively. A novel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7d6f198b93c98c206f7eade8028f126
https://doi.org/10.1016/s0040-4039(02)02245-1

Anti- Toxoplasma Activities of Antiretroviral Drugs and Interactions with Pyrimethamine and Sulfadiazine In Vitro

Autor: Francis Derouin, Maud Santillana-Hayat

Publikováno v: Antimicrobial Agents and Chemotherapy. 44:2575-2577

The anti- Toxoplasma activities of nine antiretroviral drugs were examined in vitro. Nucleoside analogs had no effect on parasite growth, whereas ritonavir and nelfinavir were inhibitory for Toxoplasma , with 50% inhibitory concentrations of 5.4 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87995336728494fe22a8b50d1afd605
https://doi.org/10.1128/aac.44.9.2575-2577.2000

Detection of Cryptosporidium, Giardia and Enterocytozoon bieneusi in surface water, including recreational areas: a one-year prospective study

Autor: Régis Pouillot, Francis Derouin, Stéphane Coupé, Karine Delabre, Maud Santillana-Hayat, Stephanie Houdart

Publikováno v: FEMS Immunology & Medical Microbiology
FEMS Immunology & Medical Microbiology, 2006, 47 (3), pp.351-359. ⟨10.1111/j.1574-695X.2006.00098.x⟩

Accidental ingestion of natural waters while bathing carries a risk of infection by waterborne protozoa such as Cryptosporidium, Giardia and, possibly, microsporidia. In order to evaluate this risk, we conducted a one-year prospective study of two re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc91e9ea46e002c12d75bcf30259fdd
https://pubmed.ncbi.nlm.nih.gov/16872371

Synthesis of new fluoroquinolones and evaluation of their in vitro activity on Toxoplasma gondii and Plasmodium spp

Autor: Rafael Gozalbes, Roger Guedj, Maud Santillana-Hayat, N. Mahmoudi, Francis Derouin, Guillaume Anquetin, Marielle Rouquayrol, Khemais Farhati, Pierre Vierling, Jacques Greiner

Publikováno v: Bioorganicmedicinal chemistry letters. 14(11)

The synthesis of four new computer-designed fluoroquinolones which have been predicted by QSAR analysis to be active against the protozoa Toxoplasma gondii is described. These compounds are inhibitory in vitro for T. gondii. One of these compounds ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979051977e0262c164748772add0e484
https://pubmed.ncbi.nlm.nih.gov/15125930