Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maud Bollenbach"'
Autor:
Maud Bollenbach, Simona Nemska, Patrick Wagner, Guillaume Camelin, François Daubeuf, Adeline Obrecht, Pascal Villa, Didier Rognan, Frédéric Bihel, Jean-Jacques Bourguignon, Martine Schmitt, Nelly Frossard
Publikováno v:
Molecules, Vol 26, Iss 2, p 391 (2021)
Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase, taking part in the activation pathway of the pro-inflammatory transcription factor NF-kB and is demonstrating a therapeutic target potential in inflammatory diseases such as asthma, p
Externí odkaz:
https://doaj.org/article/be77ee75372d43f0ba33a96af0aa47d9
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Trimethylamine (TMA) is a disease-associated metabolite produced in the human body exclusively by microbes. Gut microbes generate TMA from essential nutrients consumed in the human diet, including l-carnitine. However, our understanding
Trimethylamine (TMA) is an important gut microbial metabolite strongly associated with human disease. There are prominent gaps in our understanding of how TMA is produced from the essential dietary nutrient L-carnitine, particularly in the anoxic env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c14638f2c9f6e6b9d9cddaa32e0b1e1
https://doi.org/10.1101/2021.01.25.428109
https://doi.org/10.1101/2021.01.25.428109
Autor:
François Daubeuf, Patrick Wagner, Frédéric Bihel, Martine Schmitt, Guillaume Camelin, Adeline Obrecht, Didier Rognan, Nelly Frossard, Simona Nemska, Jean-Jacques Bourguignon, Maud Bollenbach, Pascal Villa
Publikováno v:
Molecules, Vol 26, Iss 391, p 391 (2021)
Molecules
Volume 26
Issue 2
Molecules, MDPI, 2021, 26 (2), pp.391. ⟨10.3390/molecules26020391⟩
Molecules
Volume 26
Issue 2
Molecules, MDPI, 2021, 26 (2), pp.391. ⟨10.3390/molecules26020391⟩
Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase, taking part in the activation pathway of the pro-inflammatory transcription factor NF-kB and is demonstrating a therapeutic target potential in inflammatory diseases such as asthma, p
Publikováno v:
ACS Med Chem Lett
[Image: see text] The anaerobic conversion of choline to trimethylamine (TMA) by the human gut microbiota has been linked to multiple human diseases. The potential impact of this microbial metabolic activity on host health has inspired multiple effor
Autor:
Patrick Wagner, Martine Schmitt, Thomas Fessard, Maud Bollenbach, Christophe Salomé, William Lecroq
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2019, 55 (11), pp.1623-1626. ⟨10.1039/c8cc09110b⟩
Chemical Communications, Royal Society of Chemistry, 2019, 55 (11), pp.1623-1626. ⟨10.1039/c8cc09110b⟩
International audience; A Pd cross-coupling approach for the synthesis of N-aryl-oxetanyl-amines has been developed. This method provides new building blocks potentially useful in medicinal chemistry as amide bioisosteres. The reactions are conducted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5531a181a542011dabe32cf9374f1727
https://hal-upec-upem.archives-ouvertes.fr/hal-02322869
https://hal-upec-upem.archives-ouvertes.fr/hal-02322869
Autor:
Hassan Hammoud, Stephan Kellenberger, Martine Schmitt, Maud Bollenbach, Omar Alijevic, Anand Vaithia, Viktor Trendafilov, Frédéric Bihel
Publikováno v:
ACS chemical neuroscience, vol. 9, no. 6, pp. 1357-1365
ACS Chemical Neuroscience
ACS Chemical Neuroscience, American Chemical Society (ACS), 2018, 9 (6), pp.1357-1365. ⟨10.1021/acschemneuro.7b00529⟩
ACS Chemical Neuroscience
ACS Chemical Neuroscience, American Chemical Society (ACS), 2018, 9 (6), pp.1357-1365. ⟨10.1021/acschemneuro.7b00529⟩
Acid-sensing ion channels (ASICs) are neuronal Na + -selective ion channels that open in response to extracellular acidification. They are involved in pain, fear, learning, and neurodegeneration after ischemic stroke. 2-Guanidine-4-methylquinazoline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27ac6b5a6c2d80e0d59d4affca0448c
https://serval.unil.ch/notice/serval:BIB_11B0CE680BFE
https://serval.unil.ch/notice/serval:BIB_11B0CE680BFE
Autor:
Michel Barrot, Ipek Yalcin, François Daubeuf, Nelly Frossard, Frédéric Bihel, Martine Schmitt, Patrick Wagner, Jean-Jacques Bourguignon, Maud Bollenbach, Léa J. Becker, Baptiste Letellier, Adeline Obrecht, Muris Humo, Eric Salvat, Pascal Villa
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 147, pp.163-182. ⟨10.1016/j.ejmech.2018.01.049⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 147, pp.163-182. ⟨10.1016/j.ejmech.2018.01.049⟩
4-phenylpyridin-2-yl-guanidine (5b): a new inhibitor of the overproduction of pro-inflammatory cytokines (TNFα and Il1β) was identified from a high-throughput screening of a chemical library on human peripheral blood mononuclear cells (PBMCs) after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff5ae2e3d53d5dcbce7ceeae4c559a8
https://hal.archives-ouvertes.fr/hal-02323729
https://hal.archives-ouvertes.fr/hal-02323729
Autor:
Patrick Wagner, Pedro G. V. Aquino, Jean-Jacques Bourguignon, Frédéric Bihel, Maud Bollenbach, Christophe Salomé, João Xavier de Araújo-Júnior, Martine Schmitt
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (55), pp.13676-13683. ⟨10.1002/chem.201700832⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (55), pp.13676-13683. ⟨10.1002/chem.201700832⟩
A simple, sustainable, efficient, mild, and low-cost protocol was developed for d-glucose-assisted Cu-catalyzed Ullmann reactions in water for amides, carbamates, and nitrogen-containing heterocycles. The reaction was compatible with diverse aryl/het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed47d33afe273e58878026c92b352819
https://hal.archives-ouvertes.fr/hal-02368823
https://hal.archives-ouvertes.fr/hal-02368823
Autor:
Maud Bollenbach, Martine Schmitt, Frédéric Bihel, Patrick Wagner, Jean-Jacques Bourguignon, Christophe Salomé
Publikováno v:
Tetrahedron. 70:3413-3421
Examination of the scope and limitation of the Buchwald–Hartwig cross-coupling reaction in micellar medium is reported. An array of aryl or heteroaryl halides were coupled to diverse nitrogen coupling partners using a combination of [(allyl)PdCl]2