Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Maud, Voisin"'
Autor:
Maud Voisin, Elina Shrestha, Claire Rollet, Cyrus A. Nikain, Tatjana Josefs, Mélanie Mahé, Tessa J. Barrett, Hye Rim Chang, Rachel Ruoff, Jeffrey A. Schneider, Michela L. Garabedian, Chris Zoumadakis, Chi Yun, Bara Badwan, Emily J. Brown, Adam C. Mar, Robert J. Schneider, Ira J. Goldberg, Inés Pineda-Torra, Edward A. Fisher, Michael J. Garabedian
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Voisin et al. show that reducing phosphorylation at serine 196 of LXRα (LXRα pS196) in hematopoietic cells attenuates atherosclerosis and obesity of mice fed a high-fat diet. They find that the transcriptional activity of LXRα is reprogrammed in m
Externí odkaz:
https://doaj.org/article/c5802b4ff1e54135a67ab96e212ab5fd
Autor:
Prashanth Thevkar-Nagesh, Justine Habault, Maud Voisin, Sophie E Ruff, Susan Ha, Rachel Ruoff, Xi Chen, Shruti Rawal, Tarik Zahr, Gyongyi Szabo, Inez Rogatsky, Edward A Fisher, Michael J Garabedian
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0272986 (2022)
Acyl-CoA synthetase 1 (ACSL1) is an enzyme that converts fatty acids to acyl-CoA-derivatives for lipid catabolism and lipid synthesis in general and can provide substrates for the production of mediators of inflammation in monocytes and macrophages.
Externí odkaz:
https://doaj.org/article/9d2578ffafa14325afa10509178736ab
Autor:
Gregory Segala, Marion David, Philippe de Medina, Mathias C. Poirot, Nizar Serhan, François Vergez, Aurelie Mougel, Estelle Saland, Kevin Carayon, Julie Leignadier, Nicolas Caron, Maud Voisin, Julia Cherier, Laetitia Ligat, Frederic Lopez, Emmanuel Noguer, Arnaud Rives, Bruno Payré, Talal al Saati, Antonin Lamaziere, Gaëtan Despres, Jean-Marc Lobaccaro, Silvere Baron, Cecile Demur, Fabienne de Toni, Clément Larrue, Helena Boutzen, Fabienne Thomas, Jean-Emmanuel Sarry, Marie Tosolini, Didier Picard, Michel Record, Christian Récher, Marc Poirot, Sandrine Silvente-Poirot
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Dendrogenin A, cholesterol metabolite, has tumor suppressive properties but the mechanisms are unknown. Here the authors show that Dendrogenin A can induce autophagy-mediated cell death in both melanoma and acute myeloid leukaemia.
Externí odkaz:
https://doaj.org/article/0e94ef7a2a0944adb3f0ebb1ddc02cb8
Publikováno v:
Cancer Research. 83:487-487
Breast cancer is the most common cancer in women. Unfortunately, some patients do not benefit from most therapies and may even develop resistance to previously effective treatments leading to disease progression. Therefore, treatment resistance remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57bb878a7fe8af28bfe03756f0146cd6
https://doi.org/10.1158/1538-7445.am2023-487
https://doi.org/10.1158/1538-7445.am2023-487
Publikováno v:
Biol Reprod
Spermatogenesis is a complex process that establishes male fertility and involves proper communication between the germline (spermatozoa) and the somatic tissue (Sertoli cells). Many factors that are important for spermatozoa production are also requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83f0bb47304edfecbb6f06b1c4cd90a
https://doi.org/10.1093/biolre/ioaa121
https://doi.org/10.1093/biolre/ioaa121
Autor:
Prashanth Thevkar-Nagesh, Justine Habault, Maud Voisin, Sophie E. Ruff, Susan Ha, Rachel Ruoff, Xi Chen, Shruti Rawal, Tarik Zahr, Gyongyi Szabo, Inez Rogatsky, Edward A. Fisher, Michael J. Garabedian
Publikováno v:
PloS one. 17(9)
Acyl-CoA synthetase 1 (ACSL1) is an enzyme that converts fatty acids to acyl-CoA-derivatives for lipid catabolism and lipid synthesis in general and can provide substrates for the production of mediators of inflammation in monocytes and macrophages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c0bc445717fff9b512f6437a7525c
https://pubmed.ncbi.nlm.nih.gov/36054206
https://pubmed.ncbi.nlm.nih.gov/36054206
Autor:
Elina Shrestha, Maud Voisin, Tessa J. Barrett, Hitoo Nishi, Inés Pineda-Torra, Edward A. Fisher, Michael J. Garabedian
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 5-5 (2017)
OBJECTIVES/SPECIFIC AIMS: Accumulation of cholesterol-laden macrophages in arterial walls leads to atherosclerosis. LXRs induce expression of genes that are atheroprotective in macrophages including CCR7, a chemokine receptor that promotes their emig
Externí odkaz:
https://doaj.org/article/cfe80064bf7b488eb97efc0ccebba3c7
Publikováno v:
Cancer Research. 82:2577-2577
Breast cancer is the most common cancer in women. Targeted therapies, such as hormonotherapy or immunotherapy, including checkpoint inhibitors, have revolutionized cancer treatment and are effective for most breast cancer patients. Unfortunately, som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d08c11bcf96a65748ff6b702ff32c531
https://doi.org/10.1158/1538-7445.am2022-2577
https://doi.org/10.1158/1538-7445.am2022-2577
Autor:
Melanie Mahe, Hye Rim Chang, Maud Voisin, Michael J. Garabedian, Adam C. Mar, Ira J. Goldberg, Chi Yun, Cyrus A Nikain, Claire Rollet, Robert J. Schneider, Rachel Ruoff, Chris Zoumadakis, Bara Badwan, Michela L. Garabedian, Emily J. Brown, Elina Shrestha, Tatjana Josefs, Edward A. Fisher, Jeffrey A. Schneider, Tessa J. Barrett, Ines Pineda-Torra
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Atherosclerosis and obesity share pathological features including inflammation mediated by innate and adaptive immune cells. LXRα plays a central role in the transcription of inflammatory and metabolic genes. LXRα is modulated by phosphorylation at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5b7576ab14008b257873cc95db8d93
http://europepmc.org/articles/PMC7997930
http://europepmc.org/articles/PMC7997930
Autor:
Maud Voisin, Ines Pineda-Torra, Matthew C. Gage, Elina Shrestha, Michael J. Garabedian, Natalia Becares, Edward A. Fisher
Publikováno v:
Endocrinology
Posttranslational modifications, such as phosphorylation, are a powerful means by which the activity and function of nuclear receptors such as LXRα can be altered. However, despite the established importance of nuclear receptors in maintaining metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5dded09ab00ce6482ac95ac9a54ff36
https://doi.org/10.1210/endocr/bqaa089
https://doi.org/10.1210/endocr/bqaa089