Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials

Autor: Fazekas-Singer, Judit, Berroterán-Infante, Neydher, Rami-Mark, Christina, Dumanic, Monika, Matz, Miroslawa, Willmann, Michael, Andreae, Fritz, Singer, Josef, Wadsak, Wolfgang, Mitterhauser, Markus, Jensen-Jarolim, Erika

The abstract is available here: https://uscholar.univie.ac.at/o:912157

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1726::0e3edffa105135e741f422cdd516dfd9
https://phaidra.univie.ac.at/o:912157

Generation of a Canine Anti-EGFR (ErbB-1) Antibody for Passive Immunotherapy in Dog Cancer Patients

Autor: Singer, Josef, Fazekas, Judit, Wang, Wei, Weichselbaumer, Marlene, Matz, Miroslawa, Mader, Alexander, Steinfellner, Willibald, Meitz, Sarah, Mechtcheriakova, Diana, Sobanov, Yuri, Willmann, Michael, Stockner, Thomas, Spillner, Edzard, Kunert, Renate, Jensen-Jarolim, Erika

Passive immunotherapy with monoclonal antibodies represents a cornerstone of human anticancer therapies, but has not been established in veterinary medicine yet. As the tumor-associated antigen EGFR (ErbB-1) is highly conserved between humans and dog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbc7c3c1910f07f1c662ef4c9579527a
https://europepmc.org/articles/PMC4174294/

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Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials.

Autor: Fazekas-Singer J; Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna, and University of Vienna, Vienna, Austria.; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Berroterán-Infante N; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.; Institute of Inorganic Chemistry, University of Vienna, Vienna, Austria., Rami-Mark C; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.; Institute of Inorganic Chemistry, University of Vienna, Vienna, Austria., Dumanic M; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria., Matz M; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Willmann M; Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria., Andreae F; piCHEM Forschungs- und Entwicklungs GmbH, Graz, Austria., Singer J; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.; Department of Internal Medicine II, University Hospital Krems, Karl Landsteiner University of Health Sciences, Krems an der Donau, Austria., Wadsak W; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.; Institute of Inorganic Chemistry, University of Vienna, Vienna, Austria.; CBmed GmbH-Center for Biomarker Research in Medicine, Graz, Austria., Mitterhauser M; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.; LBI Applied Diagnostics, Vienna, Austria., Jensen-Jarolim E; Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna, and University of Vienna, Vienna, Austria.; Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

Publikováno v: Oncotarget [Oncotarget] 2017 Sep 15; Vol. 8 (47), pp. 83128-83141. Date of Electronic Publication: 2017 Sep 15 (Print Publication: 2017).