CRL4-DCAF1 Ubiquitin Ligase Dependent Functions of HIV Viral Protein R and Viral Protein X

Autor: Ashley Dobransky, Mary Root, Nicholas Hafner, Matty Marcum, H. John Sharifi

Publikováno v: Viruses, Vol 16, Iss 8, p 1313 (2024)

The Human Immunodeficiency Virus (HIV) encodes several proteins that contort the host cell environment to promote viral replication and spread. This is often accomplished through the hijacking of cellular ubiquitin ligases. These reprogrammed complex

Externí odkaz: https://doaj.org/article/6db46722683c46a6ac2b16a144037ba8

Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans.

Autor: Matty MA; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America., Lau HE; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America.; Division of Biological Sciences, University of California, San Diego, La Jolla, California, United States of America., Haley JA; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America.; Neurosciences Graduate Program, University of California, San Diego, La Jolla, California, United States of America., Singh A; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America.; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America., Chakraborty A; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America., Kono K; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America., Reddy KC; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America., Hansen M; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America., Chalasani SH; Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2022 May 05; Vol. 18 (5), pp. e1010178. Date of Electronic Publication: 2022 May 05 (Print Publication: 2022).

Epithelial delamination is protective during pharmaceutical-induced enteropathy.

Autor: Espenschied ST; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710., Cronan MR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710., Matty MA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710., Mueller O; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710., Redinbo MR; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Department of Biochemistry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599., Tobin DM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710.; Department of Immunology, Duke University School of Medicine, Durham, NC 27710., Rawls JF; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710; john.rawls@duke.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Aug 20; Vol. 116 (34), pp. 16961-16970. Date of Electronic Publication: 2019 Aug 07.

Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection.

Autor: Matty MA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States.; University Program in Genetics and Genomics, Duke University, Durham, United States., Knudsen DR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States., Walton EM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States., Beerman RW; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States., Cronan MR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States., Pyle CJ; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States., Hernandez RE; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, United States.; Department of Pediatrics, University of Washington, Seattle, United States., Tobin DM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, United States.; Department of Immunology, Duke University School of Medicine, Durham, United States.

Publikováno v: ELife [Elife] 2019 Jan 29; Vol. 8. Date of Electronic Publication: 2019 Jan 29.

Infectious disease models in zebrafish.

Autor: Sullivan C; University of Maine, Orono, ME, United States., Matty MA; Duke University School of Medicine, Durham, NC, United States., Jurczyszak D; University of Maine, Orono, ME, United States., Gabor KA; National Institute of Environmental Health Sciences, Durham, NC, United States., Millard PJ; University of Maine, Orono, ME, United States., Tobin DM; Duke University School of Medicine, Durham, NC, United States., Kim CH; University of Maine, Orono, ME, United States.

Publikováno v: Methods in cell biology [Methods Cell Biol] 2017; Vol. 138, pp. 101-136. Date of Electronic Publication: 2016 Dec 02.