Digital interventions to moderate alcohol consumption in young people: a Cancer Prevention Europe overview of systematic reviews

Autor: Kevin T. McDermott, Caro Noake, Robert Wolff, Carolina Espina, Jérôme Foucaud, Karen Steindorf, Joachim Schüz, Mangesh A. Thorat, Matty Weijenberg, Linda Bauld, Jos Kleijnen

Publikováno v: Frontiers in Digital Health, Vol 5 (2023)

BackgroundStrategies to reduce alcohol consumption would contribute to substantial health benefits in the population, including reducing cancer risk. The increasing accessibility and applicability of digital technologies make these powerful tools sui

Externí odkaz: https://doaj.org/article/163a842c1e3443f395da98aec0e7b602

Cohort profile

Autor: Biljana, Gigic, Eline, van Roekel, Andreana N, Holowatyj, Stefanie, Brezina, Anne J M R, Geijsen, Arve, Ulvik, Jennifer, Ose, Janna L, Koole, Victoria, Damerell, Rama, Kiblawi, Tanja, Gumpenberger, Tengda, Lin, Gry, Kvalheim, Torsten, Koelsch, Dieuwertje E, Kok, Franzel J, van Duijnhoven, Martijn J, Bours, Andreas, Baierl, Christopher I, Li, William, Grady, Kathy, Vickers, Nina, Habermann, Martin, Schneider, Ellen, Kampman, Per Magne, Ueland, Alexis, Ulrich, Matty, Weijenberg, Andrea, Gsur, Cornelia, Ulrich

Publikováno v: BMJ Open, 12(12)
BMJ Open 12 (2022) 12
BMJ Open, 12(12):e062930. BMJ Publishing Group

PurposeThe overarching goal of the FOCUS (biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer (CRC) recurrence and survival) Consortium is to unravel the effect of folate and folate-mediated one-carbon metabolism (FOCM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fd4931e39989586077819f9a6e3566
https://doi.org/10.1136/bmjopen-2022-062930

Lamin A/C is a risk biomarker in colorectal cancer.

Autor: Naomi D Willis, Thomas R Cox, Syed F Rahman-Casañs, Kim Smits, Stefan A Przyborski, Piet van den Brandt, Manon van Engeland, Matty Weijenberg, Robert G Wilson, Adriaan de Bruïne, Christopher J Hutchison

Publikováno v: PLoS ONE, Vol 3, Iss 8, p e2988 (2008)

BackgroundA-type lamins are type V intermediate filament proteins encoded by the gene LMNA. Mutations in LMNA give rise to diverse degenerative diseases related to premature ageing. A-type lamins also influence the activity of the Retinoblastoma prot

Externí odkaz: https://doaj.org/article/db3d2cfb44af49da8812d1846bf6a64c

Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer

Autor: Craig M. Hooker, Stephanie Downing, James G Herman, Manon van Engeland, Stephen B. Baylin, Sabine C. Glöckner, Marilia Freitas Calmon, Nita Ahuja, Juan Jm Funes, Matty Weijenberg, Joo Mi Yi, Leander Van Neste, Chris Boshoff, Jana Jeschke, Kornel E. Schuebel, Christine A. Iacobuzio-Donahue, Mashaal Dhir, Kim M. Smits

Publikováno v: Clinical Cancer Research, 17(6), 1535-1545. American Association for Cancer Research Inc.

Purpose: The importance of genetic and epigenetic alterations maybe in their aggregate role in altering core pathways in tumorigenesis. Experimental Design: Merging genome-wide genomic and epigenomic alterations, we identify key genes and pathways al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7a3a409f4a4fbdf4b14e1d0bbf3435
https://doi.org/10.1158/1078-0432.ccr-10-2509

Screening policies in health impact assessment: easier decision making through cluster analysis

Autor: Bacelar-Nicolau, Leonor, Pereira Miguel, José, Saporta, Gilbert

Publikováno v: European Journal of Public Health
European Journal of Epidemiology
8th European Congress of Epidemiology
8th European Congress of Epidemiology, International Epidemiological Association, Jun 2015, Maastricht, Netherlands. pp.852, ⟨10.1007/s10654-015-0072-z⟩

International audience; Background: Screening policies to identify candidates for applying Health Impact Assessment (HIA) is generally a qualitative process. Our aim is to show how the use of multivariate exploratory statistical methods such as clust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::21b8c1004f9739457a49007842081649
https://hal-cnam.archives-ouvertes.fr/hal-03130198