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pro vyhledávání: '"Mattick, JS"'
Autor:
Pineda SS, Chin YK-Y, Undheim EAB, Senff S, Mobli M, Dauly C, Escoubas P, Nicholson GM, Kaas Q, Guo S, Herzig V, Mattick JS, King GF
Spiders are one of the most successful venomous animals, with more than 48,000 described species. Most spider venoms are dominated by cysteine-rich peptides with a diverse range of pharmacological activities. Some spider venoms contain thousands of u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::240961c966d0b603aea90b10d58fe906
https://hdl.handle.net/10453/143474
https://hdl.handle.net/10453/143474
Autor:
Mercer, TR, Clark, MB, Crawford, J, Brunck, ME, Gerhardt, DJ, Taft, RJ, Nielsen, LK, Dinger, ME, Mattick, JS
Publikováno v:
Nature Protocols. 9:989-1009
RNA sequencing (RNAseq) samples the majority of expressed genes infrequently, owing to the large size, complex splicing and wide dynamic range of eukaryotic transcriptomes. This results in sparse sequencing coverage that can hinder robust isoform ass
Autor:
Nolan, LM, Beatson, SA, Croft, L, Jones, PM, George, AM, Mattick, JS, Turnbull, L, Whitchurch, CB
Cyclic AMP (cAMP) is a signaling molecule that is involved in the regulation of multiple virulence systems of the opportunistic pathogen Pseudomonas aeruginosa. The intracellular concentration of cAMP in P. aeruginosa cells is tightly controlled at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dd23aecc6fbbc333df85fc3dbff85932
http://hdl.handle.net/10044/1/52517
http://hdl.handle.net/10044/1/52517
Autor:
Whitchurch, CB, Beatson, SA, Comolli, JC, Jakobsen, T, Sargent, JL, Bertrand, JJ, West, J, Klausen, M, Waite, LL, Kang, PJ, Tolker-Nielsen, T, Mattick, JS, Engel, JN
Publikováno v:
Whitchurch, C B; Beatson, S A; Comolli, J C; Jakobsen, T; Sargent, J L; Bertrand, J J; et al.(2005). Pseudomonas aeruginosa fimL regulates multiple virulence functions by intersecting with Vfr-modulated pathways. Molecular Microbiology, 55(5), 1357-1378. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1v73077h
Virulence of Pseudomonas aeruginosa involves the co-ordinate expression of a range of factors including type IV pili (tfp), the type III secretion system (TTSS) and quorum sensing. Tfp are required for twitching motility, efficient biofilm formation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::80a3a2613d60931c8bb9658b68b75032
http://www.escholarship.org/uc/item/1v73077h
http://www.escholarship.org/uc/item/1v73077h
Autor:
Whitchurch, CB, Leech, AJ, Young, MD, Kennedy, D, Sargent, JL, Bertrand, JJ, Semmler, ABT, Mellick, AS, Martin, PR, Alm, RA, Hobbs, M, Beatson, SA, Huang, B, Nguyen, L, Commolli, JC, Engel, JN, Darzins, A, Mattick, JS
Virulence of the opportunistic pathogen Pseudomonas aeruginosa involves the coordinate expression of a wide range of virulence factors including type IV pili which are required for colonization of host tissues and are associated with a form of surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::2122d67d9db060248850dae40c3b58bd
https://hdl.handle.net/10453/8598
https://hdl.handle.net/10453/8598
Vfr, a homolog of Escherichia coli cyclic AMP (cAMP) receptor protein, has been shown to regulate quorum sensing, exotoxin A production, and regA transcription in Pseudomonas aeruginosa. We identified a twitching motility-defective mutant that carrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::26ff8c02a91666a0a869fb9a3fcfc2b5
https://hdl.handle.net/10453/8612
https://hdl.handle.net/10453/8612
Transposon mutagenesis was used to identify a new locus required for twitching motility in Pseudomonas aeruginosa. Four Tn5-B21 mutants which lacked twitching motility and a fifth which exhibited impaired motility were found to map to the same KpnI r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::991a23766338617f782410efc8e77a05
https://hdl.handle.net/10453/9507
https://hdl.handle.net/10453/9507
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