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pro vyhledávání: '"Mattias Nowenwik"'
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery
Background: Many substances used in inhalation research are water soluble and can be administered as nebulized solutions. Typical examples are therapeutic, small-molecular agents, or macromolecules. Another category is a number of water-soluble agent
Autor:
M. Luísa Corvo, Beatriz Noriega-Fernandes, Mattias Nowenwik, Maria Malmlöf, Eunice Costa, Per Gerde
Publikováno v:
International journal of pharmaceutics. 607
The composition, morphology and dissolution profile of particles and micro-sized agglomerates delivered upon inhalation may have a significant impact on the product clinical effect. However, although several efforts are ongoing, a methodology that co
Autor:
Hermann Mascher, Per Gerde, Ewa Selg, John Burns, Mattias Nowenwik, Kristof Meelich, Iwona Rådberg, Maria Malmlöf
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 139
The surface area of the air/liquid interface in the lungs is substantial, so deposited doses of aerosol medicines per interface surface area when administered via the inhalation route is always quite low. However, in most in vitro systems used for di