Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mattias Möller"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Genetic determinants underlying most human blood groups are now clarified but variation in expression levels remains largely unexplored. By developing a bioinformatics pipeline analyzing GATA1/Chromatin immunoprecipitation followed by sequen
Externí odkaz:
https://doaj.org/article/df58f16718ab4ee09d3cf4402557b60f
Autor:
Nicole Thornton, Vanja Karamatic Crew, Louise Tilley, Carole A. Green, Chwen Ling Tay, Rebecca E. Griffiths, Belinda K. Singleton, Frances Spring, Piers Walser, Abdul Ghani Alattar, Benjamin Jones, Rosalind Laundy, Jill R. Storry, Mattias Möller, Lorna Wall, Richard Charlewood, Connie M. Westhoff, Christine Lomas-Francis, Vered Yahalom, Ute Feick, Axel Seltsam, Beate Mayer, Martin L. Olsson, David J. Anstee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The molecular basis of the clinically important MAM blood group antigen present in most humans is unknown. We identify EMP3 as its encoding gene, establishing MAM as a new blood group system, and demonstrate the role of EMP3 in erythropoiesis through
Externí odkaz:
https://doaj.org/article/e938a7d9bc5f42fa84a3d130a0d92402
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Glycans are biologically important structures synthesised by glycosyltransferase (GT) enzymes. Disruptive genetic null variants in GT genes can lead to serious illness but benign phenotypes are also seen, including antigenic differences on t
Externí odkaz:
https://doaj.org/article/fa31ee5286a445bca22b006c26b48c18
Publikováno v:
Blood Advances, Vol 1, Iss 3, Pp 240-249 (2016)
Abstract: Blood group genotyping has recently developed into a clinical tool to improve compatibility of blood transfusions and management of pregnancies. Next-generation sequencing (NGS) is rapidly moving toward routine practice for patient and dono
Externí odkaz:
https://doaj.org/article/18f54d147b4c4e67a7c19efdc02849aa
Publikováno v:
Biochemistry and Biophysics Reports, Vol 19, Iss , Pp - (2019)
Sda is a high-frequency carbohydrate histo-blood group antigen, GalNAcβ1-4(NeuAcα2-3)Galβ, implicated in pathogen invasion, cancer, xenotransplantation and transfusion medicine. Complete lack of this glycan epitope results in the Sd(a−) phenotyp
Externí odkaz:
https://doaj.org/article/7e21b940638b4007aae238d9a2f14d89
Autor:
Beate Mayer, Vanja Karamatic Crew, Louise Tilley, Richard Charlewood, Chwen Ling Tay, Vered Yahalom, D J Anstee, Belinda K. Singleton, Abdul Ghani Alattar, Ute Feick, Axel Seltsam, Nicole Thornton, Jill R. Storry, C A Green, Frances A. Spring, Benjamin Jones, Rebecca E. Griffiths, Rosalind Laundy, Piers Walser, Connie M. Westhoff, Mattias Möller, Christine Lomas-Francis, Lorna Wall, Martin L. Olsson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
The clinically important MAM blood group antigen is present on haematopoietic cells of all humans except rare MAM-negative individuals. Its molecular basis is unknown. By whole-exome sequencing we identify EMP3, encoding epithelial membrane protein 3
Publikováno v:
Transfusion. 58:2036-2045
BACKGROUND: The FORS histo-blood group system was described in 2013 and much remains to be investigated regarding its genetic and immunohematologic characteristics, as well as its clinical importance. While presence of the c.887G>A-mutated GBGT1 gene
Autor:
Yan Quan Lee, Linda Björkman, Mattias Möller, Jill R. Storry, Sven Kjellström, Karina Vidovic, Martin L. Olsson
Publikováno v:
Blood. 132:334-338
The Xga blood group is differentially expressed on erythrocytes from men and women. The underlying gene, PBDX, was identified in 1994, but the molecular background for Xga expression remains undefined. This gene, now designated XG, partly resides in
Autor:
Karina Vidovic, Sven Kjellström, Martin L. Olsson, Mattias Möller, Åsa Hellberg, Julia S. Westman, Linn Stenfelt
Publikováno v:
Blood. 131:1611-1616
P1 and Pk are glycosphingolipid antigens synthesized by the A4GALT-encoded α1,4-galactosyltransferase, using paragloboside and lactosylceramide as acceptor substrates, respectively. In addition to the compatibility aspects of these histo-blood group
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Glycans are biologically important structures synthesised by glycosyltransferase (GT) enzymes. Disruptive genetic null variants in GT genes can lead to serious illness but benign phenotypes are also seen, including antigenic differences on the red bl