Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mattias Leino"'
Autor:
Doroteya Raykova, Despoina Kermpatsou, Tony Malmqvist, Philip J. Harrison, Marie Rubin Sander, Christiane Stiller, Johan Heldin, Mattias Leino, Sara Ricardo, Anna Klemm, Leonor David, Ola Spjuth, Kalyani Vemuri, Anna Dimberg, Anders Sundqvist, Maria Norlin, Axel Klaesson, Caroline Kampf, Ola Söderberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Determining the levels of protein–protein interactions is essential for the analysis of signaling within the cell, characterization of mutation effects, protein function and activation in health and disease, among others. Herein, we descri
Externí odkaz:
https://doaj.org/article/62ebc0c6a0da437aba3d465a5bbe05c2
Autor:
Doroteya Raykova, Despoina Kermpatsou, Tony Malmqvist, Philip J. Harrison, Marie Rubin Sander, Christiane Stiller, Johan Heldin, Mattias Leino, Sara Ricardo, Anna Klemm, Leonor David, Ola Spjuth, Kalyani Vemuri, Anna Dimberg, Anders Sundqvist, Maria Norlin, Axel Klaesson, Caroline Kampf, Ola Söderberg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1b52ed4d7464442c978e7ac4bff1d6a2
Autor:
Axel Klaesson, Karin Grannas, Tonge Ebai, Johan Heldin, Björn Koos, Mattias Leino, Doroteya Raykova, Johan Oelrich, Linda Arngården, Ola Söderberg, Ulf Landegren
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract We have redesigned probes for in situ proximity ligation assay (PLA), resulting in more efficient localized detection of target proteins. In situ PLA depends on recognition of target proteins by pairs of antibody-oligonucleotide conjugates (
Externí odkaz:
https://doaj.org/article/75ad5875c3544fa48fd0da457da9bb4f
Autor:
Mattias Leino, Ola Söderberg
Hybridization chain-reaction (HCR) is technique to generate a linear polymerization of oligonucleotide hairpins, used in multiple molecular biology methods. The HCR reaction is dependent on that every hairpin is metastable in the absence of a trigger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dbc804dbda8eddac2b9cb87ac47166
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-496885
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-496885
Publikováno v:
In Biomaterials February 2014 35(6):1797-1806
Autor:
Bjoern Koos, Ola Söderberg, Johan Heldin, Mattias Leino, Marie Rubin Sander, Despoina Kermpatsou, Doroteya Raykova
Publikováno v:
Molecular Systems Design & Engineering. 4:1058-1065
Proximity based detection methods are invaluable tools in the field of molecular biology, increasing selectivity and allowing for analysis of protein interactions. ProxHCR utilizes pairs of antibodies labelled with oligonucleotides to probe for proxi
Autor:
Laura Francés-Soriano, Mattias Leino, Marcelina Cardoso Dos Santos, Daniel Kovacs, K. Eszter Borbas, Ola Söderberg, Niko Hildebrandt
Fluorescence signal enhancementviaisothermal nucleic acid amplification is an important approach for sensitive imaging of intra- or extracellular nucleic acid or protein biomarkers. Rolling circle amplification (RCA) is frequently applied for fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::d7c94d3bea48e39e2d80be974eca6988
https://zenodo.org/record/4786693
https://zenodo.org/record/4786693
Autor:
Johan, Heldin, Marie Rubin, Sander, Mattias, Leino, Sara, Thomsson, Johan, Lennartsson, Ola, Söderberg
Publikováno v:
Experimental cell research. 380(1)
The role of plasma membrane composition and dynamics in the activation process of receptor tyrosine kinases (RTKs) is still poorly understood. In this study we have investigated how signaling via the RTK, platelet-derived growth factor β-receptor (P
Autor:
Carolina Åstrand, Robert McKean, Veronique Chotteau, Mattias Leino, Nanayaa F. Hughes-Brittain, Brendan Robb
Advances in human pluripotent cell cultivation and differentiation protocols have led to production of stem cell-derived progenitors as a promising cell source for replacement therapy. Three-dimensional (3-D) culture is a better mimic of the natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f541357accc3de1c1ffac005df51f3f
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-225172
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-225172
Autor:
Laura Francés-Soriano, Daniel Kovacs, Niko Hildebrandt, Marcelina Cardoso Dos Santos, Mattias Leino, Ola Söderberg, K. Eszter Borbas
Publikováno v:
Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2020, ⟨10.1021/acs.analchem.0c04828⟩
Analytical Chemistry, 2020, ⟨10.1021/acs.analchem.0c04828⟩
Analytical Chemistry, American Chemical Society, 2020, ⟨10.1021/acs.analchem.0c04828⟩
Analytical Chemistry, 2020, ⟨10.1021/acs.analchem.0c04828⟩
Fluorescence signal enhancement via isothermal nucleic acid amplification is an important approach for sensitive imaging of intra- or extracellular nucleic acid or protein biomarkers. Rolling circle amplification (RCA) is frequently applied for fluor