Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Mattias Collin"'
Pathogen-driven degradation of endogenous and therapeutic antibodies during streptococcal infections
Autor:
Alejandro Gomez Toledo, Eleni Bratanis, Erika Velásquez, Sounak Chowdhury, Berit Olofsson, James T. Sorrentino, Christofer Karlsson, Nathan E. Lewis, Jeffrey D. Esko, Mattias Collin, Oonagh Shannon, Johan Malmström
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Group A streptococcus (GAS) is a major bacterial pathogen responsible for both local and systemic infections in humans. The molecular mechanisms that contribute to disease heterogeneity remain poorly understood. Here we show that the transit
Externí odkaz:
https://doaj.org/article/bce37cf8902b4d488654606c706f6c47
Autor:
Sujeesh Sebastian, Felix Tandberg, Yang Liu, Deepak B. Raina, Magnus Tägil, Mattias Collin, Lars Lidgren
Publikováno v:
Bone & Joint Research, Vol 11, Iss 11, Pp 787-802 (2022)
AimsThere is a lack of biomaterial-based carriers for the local delivery of rifampicin (RIF), one of the cornerstone second defence antibiotics for bone infections. RIF is also known for causing rapid development of antibiotic resistance when given a
Externí odkaz:
https://doaj.org/article/f590a324d2eb480f9c0b2108c60bcfab
Autor:
Lotta Happonen, Mattias Collin
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 200 (2024)
Streptococcus pyogenes, or Group A Streptococcus, is an exclusively human pathogen that causes a wide variety of diseases ranging from mild throat and skin infections to severe invasive disease. The pathogenesis of S. pyogenes infection has been exte
Externí odkaz:
https://doaj.org/article/ae87acb3191444c38bc42dcfce927b0a
Autor:
Daniela Kao, Heike Danzer, Mattias Collin, Andrea Groß, Jutta Eichler, Jerko Stambuk, Gordan Lauc, Anja Lux, Falk Nimmerjahn
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2376-2385 (2015)
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody prepa
Externí odkaz:
https://doaj.org/article/1946d3ce49244901ad3235a94c8a7d9b
Autor:
Kutty Selva Nandakumar, Mattias Collin, Kaisa E. Happonen, Susanna L. Lundström, Allyson M. Croxford, Bingze Xu, Roman A. Zubarev, Merrill J. Rowley, Anna M. Blom, Christian Kjellman, Rikard Holmdahl
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Endo-β-N-acetylglucosaminidase (EndoS) is a family 18 glycosyl hydrolase secreted by Streptococcus pyogenes. Recombinant EndoS hydrolyzes the β-1,4-di-N-acetylchitobiose core of the N-linked complex type glycan on the asparagine 297 of the γ-chain
Externí odkaz:
https://doaj.org/article/82fb0ce5d6694c2f9a4f650dd1ab78bd
Autor:
Mattias Collin
Publikováno v:
EBioMedicine, Vol 17, Iss C, p 15 (2017)
Externí odkaz:
https://doaj.org/article/1ab19f00faf544a0842864298a71d125
Autor:
Julia Garbe, Jonathan Sjögren, Eoin F J Cosgrave, Weston B Struwe, Marta Bober, Anders I Olin, Pauline M Rudd, Mattias Collin
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91035 (2014)
Glycosidases are widespread among bacteria. The opportunistic human pathogen Enterococcus faecalis encodes several putative glycosidases but little is known about their functions. The identified endo-β-N-acetylglucosaminidase EndoE has activity on t
Externí odkaz:
https://doaj.org/article/e090576cd0284bf09c5625ba6c8699b0
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e85317 (2014)
Endo-β-N-acetylglucosaminidase (EndoS) has been shown to act as a potent pathogen-derived immunomodulatory molecule in autoimmune diseases. Here we investigated how EndoS treatment reduces the pathogenicity of rabbit anti-mCOL7 IgG using different e
Externí odkaz:
https://doaj.org/article/dfdd138abfcf4b6f9818fc60eab9ad48
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58129 (2013)
Chemokines and chemokine receptor-mediated effects are important mediators of the immunological response and cure in human leishmaniasis. However, in addition to their signalling properties for leukocytes, many chemokines have also been shown to act
Externí odkaz:
https://doaj.org/article/e96ba3d053e04726b167c91ecc780bf4
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20345 (2011)
Streptococcus pyogenes is an important human pathogen and surface structures allow it to adhere to, colonize and invade the human host. Proteins containing leucine rich repeats (LRR) have been identified in mammals, viruses, archaea and several bacte
Externí odkaz:
https://doaj.org/article/280aa4033a6040dbb0a53857fdeb24c8