Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mattias C. U. Gustafsson"'
Autor:
Larry G. Higgins, Wojciech G. Garbacz, Mattias C. U. Gustafsson, Sitheswaran Nainamalai, Peter R. Ashby, C. Roland Wolf, Colin N. A. Palmer
Publikováno v:
PPAR Research, Vol 2012 (2012)
The nuclear receptor, NR1C2 or peroxisome proliferator-activated receptor (PPAR)-δ, is ubiquitously expressed and important for placental development, fatty acid metabolism, wound healing, inflammation, and tumour development. PPARδ has been hypoth
Externí odkaz:
https://doaj.org/article/15b3b22a60b4410cabade62c119dcb71
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81303 (2013)
Recent studies indicate that defective activity of complement factor H (FH) is associated with several human diseases, suggesting that pure FH may be used for therapy. Here, we describe a simple method to isolate human FH, based on the specific inter
Externí odkaz:
https://doaj.org/article/0fe95e9916174108bbac3b6cdc3f2f44
Autor:
Mattias C U Gustafsson, Jonas Lannergård, O Rickard Nilsson, Bodil M Kristensen, John E Olsen, Claire L Harris, Rafael L Ufret-Vincenty, Margaretha Stålhammar-Carlemalm, Gunnar Lindahl
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003323 (2013)
Many pathogens express a surface protein that binds the human complement regulator factor H (FH), as first described for Streptococcus pyogenes and the antiphagocytic M6 protein. It is commonly assumed that FH recruited to an M protein enhances virul
Externí odkaz:
https://doaj.org/article/bedf237b683546428ff1fd3168c1671f
Autor:
Malgorzata Romanowska, Louise Reilly, Colin N A Palmer, Mattias C U Gustafsson, John Foerster
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9701 (2010)
Psoriasis is one of the most frequent skin diseases world-wide. The disease impacts enormously on affected patients and poses a huge financial burden on health care providers. Several lines of evidence suggest that the nuclear hormone receptor peroxi
Externí odkaz:
https://doaj.org/article/d8a5ebf8cd444ad7bb45120b9e48383e
Autor:
Mattias C. U. Gustafsson, Margaretha Stålhammar-Carlemalm, Anna Norrby-Teglund, Jonas Lannergård, Johan Waldemarsson, Gunnar Lindahl
Publikováno v:
Cell Host & Microbe. 10(2):147-157
SummarySequence variation of antigenic proteins allows pathogens to evade antibody attack. The variable protein commonly includes a hypervariable region (HVR), which represents a key target for antibodies and is therefore predicted to be immunodomina
Autor:
Caroline Düringer, Ali Hamiche, Mattias C. U. Gustafsson, Lotta Gustafsson, Ann-Kristin Mossberg, Patrick Brest, Catharina Svanborg
Publikováno v:
Cancer Research. 67:11327-11334
Histone deacetylase inhibitors (HDIs) and HAMLET (human α-lactalbumin made lethal to tumor cells) interact with histones, modify the structure of chromatin, and trigger tumor cell death. This study investigated how the combination of HDIs and HAMLET
Autor:
Margaretha Stålhammar-Carlemalm, Jonas Lannergård, Mattias C. U. Gustafsson, Jenny L. Persson, Anna Norrby-Teglund, Bodil M. Kristensen, Gunnar Lindahl
Publikováno v:
MicrobiologyOpen
Lannergård, J, Kristensen, B M, Gustafsson, M C U, Persson, J J, Norrby-Teglund, A, Stålhammar-Carlemalm, M & Lindahl, C G 2015, ' Sequence variability is correlated with weak immunogenicity in Streptococcus pyogenes M protein ', MicrobiologyOpen, vol. 4, no. 5, pp. 774-789 . https://doi.org/10.1002/mbo3.278
Lannergård, J, Kristensen, B M, Gustafsson, M C U, Persson, J J, Norrby-Teglund, A, Stålhammar-Carlemalm, M & Lindahl, C G 2015, ' Sequence variability is correlated with weak immunogenicity in Streptococcus pyogenes M protein ', MicrobiologyOpen, vol. 4, no. 5, pp. 774-789 . https://doi.org/10.1002/mbo3.278
The M protein of Streptococcus pyogenes, a major bacterial virulence factor, has an amino-terminal hypervariable region (HVR) that is a target for type-specific protective antibodies. Intriguingly, the HVR elicits a weak antibody response, indicating
Autor:
Ewa Ehrenborg, Colin N. A. Palmer, Paul Targett-Adams, Mattias C. U. Gustafsson, Marion McElwee, John McLauchlan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1728:95-104
Lipid droplets are cytoplasmic organelles which serve as storage sites for neutral lipids. Adipose differentiation-related protein (ADRP) is intrinsically associated with the surface of lipid droplets and is believed to play a major role in the maint
Autor:
Stephen K Chapman, Ker R. Marshall, Mattias C. U. Gustafsson, Claes von Wachenfeldt, Olivier Roitel, Antonio M Pessegueiro, Myles R Cheesman, Michael A. Noble, Armand J. Fulco, Andrew W. Munro
Publikováno v:
Biochemistry. 43:5474-5487
The cyp102A2 and cyp102A3 genes encoding the two Bacillus subtilis homologues (CYP102A2 and CYP102A3) of flavocytochrome P450 BM3 (CYP102A1) from Bacillus megaterium have been cloned, expressed in Escherichia coli, purified, and characterized spectro
Publikováno v:
Archives of Microbiology. 176:459-464
Bacillus subtilis strain 168 encodes two flavocytochromes P450, Cyp102A2 and Cyp102A3. The cyp102A3 gene is preceded by, and organized in an operon with, a gene for a transcriptional regulator, encoded by fatR. The paralogous gene, cyp102A2, is most