Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mattias Brofelth"'
Autor:
Anna Isinger Ekstrand, Carl A.K. Borrebaeck, Christer Wingren, Ronnie Jansson, Shashank Gour, Ulrika Axelsson, Anders Kvist, My Hedhammar, Björn Elleby, Mattias Brofelth
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-6 (2020)
Communications Biology
Communications Biology
The composition of serum proteins is reflecting the current health status and can, with the right tools, be used to detect early signs of disease, such as an emerging cancer. An earlier diagnosis of cancer would greatly increase the chance of an impr
Autor:
Hinnerk Saathoff, Benjamin L. Parker, Nicholas E. Shepherd, Mario Torrado, Ana P. G. Silva, Daniel P. Ryan, Mattias Brofelth, Jason Low, Sarah R. Webb, Joel P. Mackay
Publikováno v:
Journal of Biological Chemistry. 291:15853-15866
Chromatin remodeling enzymes act to dynamically regulate gene accessibility. In many cases, these enzymes function as large multicomponent complexes that in general comprise a central ATP-dependent Snf2 family helicase that is decorated with a variab
Autor:
Joel P. Mackay, Daniel P. Ryan, Benjamin L. Parker, Hinnerk Saathoff, Jason Low, Mattias Brofelth, Nicholas E. Shepherd, Ana P. G. Silva, Anne Trinh, Sarah R. Webb
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:960-965
We have developed an approach for directly isolating an intact multi-protein chromatin remodeling complex from mammalian cell extracts using synthetic peptide affinity reagent 4. FOG1(1–15), a short peptide sequence known to target subunits of the
Autor:
Kim Lambertsen Larsen, Lars Wagner Städe, Thorbjørn Terndrup Nielsen, Mattias Brofelth, Christer Wingren, Anna Isinger Ekstrand, Linn Petersson Edfeldt, Rebeka Kovačič, Laurent Duroux
Publikováno v:
Brofelth, M, Städe, L W, Ekstrand, A I, Edfeldt, L P, Kovačič, R, Nielsen, T T, Larsen, K L, Duroux, L & Wingren, C 2017, ' Site-specific photocoupling of pBpa mutated scFv antibodies for use in affinity proteomics ', B B A-Proteins and Proteomics, vol. 1865, no. 8, pp. 985-996 . https://doi.org/10.1016/j.bbapap.2017.03.007
Recombinant antibody libraries can provide a source of renewable and high-performing binders tailored for use in affinity proteomics. In this context, the process of generating site-specific 1:1 tagging/functionalization and/or orientated surface imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b6366ed30bd347daa4441a35b51099
https://vbn.aau.dk/da/publications/8f925422-fe99-4a07-8cbf-dbce2127c231
https://vbn.aau.dk/da/publications/8f925422-fe99-4a07-8cbf-dbce2127c231
Autor:
Carl A.K. Borrebaeck, Kim Lambertsen Larsen, Niclas Olsson, Linn Petersson, Stefanie Gärtner, Martin Sandgren, Lars Wagner Städe, Jacob Vallkil, Christer Wingren, Elin Fors, Laurent Duroux, Mattias Brofelth
Publikováno v:
Petersson, L, Städe, L W, Brofelth, M, Gärtner, S, Fors, E, Sandgren, M, Vallkil, J, Olsson, N, Larsen, K L, Borrebaeck, C A K, Duroux, L & Wingren, C 2014, ' Molecular design of recombinant scFv antibodies for site-specific photocoupling to β-cyclodextrin in solution and onto solid support ', Biochimica et Biophysica Acta-Proteins and Proteomics, vol. 1844, no. 12, pp. 2164-2173 . https://doi.org/10.1016/j.bbapap.2014.08.010
The ability to design and tailor-make antibodies to meet the biophysical demands required by the vast range of current and future antibody-based applications within biotechnology and biomedicine will be essential. In this proof-of-concept study, we h