Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Mattias Belting"'
Autor:
Emre Can Tuysuz, Eleni Mourati, Rebecca Rosberg, Aleksandra Moskal, Chrysostomi Gialeli, Elinn Johansson, Valeria Governa, Mattias Belting, Alexander Pietras, Anna M. Blom
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background The complement inhibitor CSMD1 acts as a tumor suppressor in various types of solid cancers. Despite its high level of expression in the brain, its function in gliomas, malignant brain tumors originating from glial cells, has not
Externí odkaz:
https://doaj.org/article/2cfba0cfd2094dd8a624c0aef401ef77
Autor:
Christopher Godina, Mattias Belting, Johan Vallon-Christersson, Karolin Isaksson, Ana Bosch, Helena Jernström
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Combining information from the tumor microenvironment (TME) with PAM50 Risk of Recurrence (ROR) score could improve breast cancer prognostication. Caveolin-1 (CAV1) is a marker of an active TME. CAV1 is a membrane protein involved in cell si
Externí odkaz:
https://doaj.org/article/97f3d582073e472a88a489644135df4a
Autor:
Kelin Gonçalves de Oliveira, Anna Bång-Rudenstam, Sarah Beyer, Axel Boukredine, Hugo Talbot, Valeria Governa, Maria C. Johansson, Ann-Sofie Månsson, Karin Forsberg-Nilsson, Johan Bengzon, Johan Malmström, Charlotte Welinder, Mattias Belting
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract Immunotherapies with antibody–drug-conjugates (ADC) and CAR-T cells, targeted at tumor surface antigens (surfaceome), currently revolutionize clinical oncology. However, target identification warrants a better understanding of the surfaceo
Externí odkaz:
https://doaj.org/article/2420e036341048829943fa3b910fe88d
Autor:
Christopher Godina, Somayeh Khazaei, Mattias Belting, Johan Vallon-Christersson, Björn Nodin, Karin Jirström, Karolin Isaksson, Ana Bosch, Helena Jernström
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305222 (2024)
BackgroundCurrently, there are few treatment-predictive and prognostic biomarkers in triple-negative breast cancer (TNBC). Caveolin-1 (CAV1) is linked to chemoresistance and several important processes involved in tumor progression and metastasis, su
Externí odkaz:
https://doaj.org/article/b8af823829db42e29aa5801ab12f0df5
Autor:
Erik Ehinger, Jan Kopecky, Anna Darabi, Edward Visse, Charlotte Edvardsson, Gregor Tomasevic, David Cederberg, Mattias Belting, Johan Bengzon, Peter Siesjö
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Purpose Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Despite the best available treatment, prognosis remains poor. Current standard therapy consists of surgical removal of the tumor followed by radiotherapy
Externí odkaz:
https://doaj.org/article/11d4701526cb419e84a12c1692767331
Autor:
Amra Jujić, Christopher Godina, Mattias Belting, Olle Melander, Jens Juul Holst, Emma Ahlqvist, Maria F. Gomez, Peter M. Nilsson, Helena Jernström, Martin Magnusson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Concerns have been raised regarding a potentially increased risk of cancer associated with treatment with glucagon-like peptide-1 (GLP-1) receptor agonists. Here, we explored whether fasting and oral glucose tolerance test post-challenge glu
Externí odkaz:
https://doaj.org/article/b4e8109620254c1282c06da734ab948b
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth, recurrence and patient prognos
Externí odkaz:
https://doaj.org/article/9fd57575b391431ea243f0e6acf21815
Autor:
Christopher Godina, Vineesh Indira Chandran, Magdalena Barbachowska, Helga Tryggvadottir, Björn Nodin, Edward Visse, Signe Borgquist, Karin Jirström, Karolin Isaksson, Ana Bosch, Mattias Belting, Helena Jernström
Publikováno v:
Translational Oncology, Vol 22, Iss , Pp 101464- (2022)
Background: Caveolin-1 (CAV1) is associated with cholesterol-rich membrane raft domains and is a master regulator of cell signaling and membrane transport. Here, we investigated CAV1’s role in cellular compartments of breast cancer in relation to s
Externí odkaz:
https://doaj.org/article/d9798d3b49bb4a7c89a22c3134b4a34a
Publikováno v:
Cancers, Vol 15, Iss 12, p 3176 (2023)
Circulating tumor cells (CTCs) may provide a liquid biopsy approach to disease monitoring in small cell lung cancer (SCLC), a particularly aggressive tumor subtype. Yet, the prognostic role of CTCs during and after treatment in relation to baseline r
Externí odkaz:
https://doaj.org/article/5f61ed5e045c42b386ef583e75204909
Autor:
Svenja Offer, Julien A. Menard, Julio Enríquez Pérez, Kelin G. de Oliveira, Vineesh Indira Chandran, Maria C. Johansson, Anna Bång-Rudenstam, Peter Siesjö, Anna Ebbesson, Ingrid Hedenfalk, Pia C. Sundgren, Anna Darabi, Mattias Belting
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Primary brain tumors, in particular glioblastoma (GBM), remain among the most challenging cancers. Like most malignant tumors, GBM is characterized by hypoxic stress that triggers paracrine, adaptive responses, such as angiogenesi
Externí odkaz:
https://doaj.org/article/139878c7c70b43af97497255555f7499