3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer

Autor: Pere Llinàs-Arias, Miquel Ensenyat-Méndez, Javier I. J. Orozco, Sandra Íñiguez-Muñoz, Betsy Valdez, Chuan Wang, Anja Mezger, Eunkyoung Choi, Yan Zhou Tran, Liqun Yao, Franziska Bonath, Remi-André Olsen, Mattias Ormestad, Manel Esteller, Mathieu Lupien, Diego M. Marzese

Publikováno v: BMC Genomic Data, Vol 24, Iss 1, Pp 1-7 (2023)

Abstract Objectives Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype with limited treatment options. Unlike other breast cancer subtypes, the scarcity of specific therapies and greater frequencies of distant metastase

Externí odkaz: https://doaj.org/article/ae6de6960e06403498b0edcc6089e71b

Index hopping on the Illumina HiseqX platform and its consequences for ancient DNA studies

Autor: Tom van der Valk, Katerina Guschanski, Francesco Vezzi, Mattias Ormestad, Love Dalén

Publikováno v: Molecular Ecology Resources. 20:1171-1181

The high-throughput capacities of the Illumina sequencing platforms and the possibility to label samples individually have encouraged wide use of sample multiplexing. However, this practice results in read misassignment (usually

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cc5f8aacf3fe0e1ebfaddbdc23452b
https://doi.org/10.1111/1755-0998.13009

Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle

Autor: Margit Mahlapuu, Juleen R. Zierath, Yun Chau Long, Mattias Ormestad, Annika Nerstedt, Elaine Vieira, Pablo M. Garcia-Roves, Elisabeth C. Nilsson

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 295:E1032-E1037

Circadian clocks coordinate physiological, behavioral, and biochemical events with predictable daily environmental changes by a self-sustained transcriptional feedback loop. CLOCK and ARNTL are transcriptional activators that regulate Per and Cry gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d25ab7cb9d98434487ff336833d20bb
https://doi.org/10.1152/ajpendo.90510.2008

Foxf1andFoxf2control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

Autor: Bengt Johansson, Naoyuki Miura, Jeanette Astorga, Henrik Landgren, Tao Wang, Mattias Ormestad, Peter Carlsson

Publikováno v: Ormestad, M, Astorga (Johansson), J, Landgren, H, Wang, T, Johansson, B R, Miura, N & Carlsson, P 2006, ' Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production ', Development, vol. 133, no. 5, pp. 833-43 . https://doi.org/10.1242/dev.02252

Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. In the adult, the same types of signals control epithelial proliferation and survival, which account for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a468aba618f97508f4726df69a8d28b1
https://doi.org/10.1242/dev.02252

A comparative gene expression database for invertebrates

Autor: Mattias Ormestad, Mark Q. Martindale, Eric Röttinger

Publikováno v: EvoDevo
EvoDevo, BioMed Central, 2011, 2 (1), pp.17. ⟨10.1186/2041-9139-2-17⟩
EvoDevo, Vol 2, Iss 1, p 17 (2011)

Background As whole genome and transcriptome sequencing gets cheaper and faster, a great number of 'exotic' animal models are emerging, rapidly adding valuable data to the ever-expanding Evo-Devo field. All these new organisms serve as a fantastic re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3276691219fcb0362456590139abe975
https://hal.archives-ouvertes.fr/hal-02411412