Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Mattias, Ekstedt"'
Autor:
Henrik Podéus, Christian Simonsson, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Peter Lundberg, William Lövfors, Gunnar Cedersund
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Alcohol consumption is associated with a wide variety of preventable health complications and is a major risk factor for all-cause mortality in the age group 15-47 years. To reduce dangerous drinking behavior, eHealth applications have shown
Externí odkaz:
https://doaj.org/article/497f6a94a18c45959cbf135c32b0e9c3
Autor:
Patrik Nasr, Mikael Forsgren, Wile Balkhed, Cecilia Jönsson, Nils Dahlström, Christian Simonsson, Shan Cai, Anna Cederborg, Martin Henriksson, Henrik Stjernman, Martin Rejler, Daniel Sjögren, Gunnar Cedersund, Wolf Bartholomä, Ingvar Rydén, Peter Lundberg, Stergios Kechagias, Olof Dahlqvist Leinhard, Mattias Ekstedt
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Liver cirrhosis, the advanced stage of many chronic liver diseases, is associated with escalated risks of liver-related complications like decompensation and hepatocellular carcinoma (HCC). Morbidity and mortality in cirrhosis pat
Externí odkaz:
https://doaj.org/article/827a5b3938b54e0ea768519d24f890db
Autor:
Jane Knöchel, Linnéa Bergenholm, Eman Ibrahim, Stergios Kechagias, Sara Hansson, Mathias Liljeblad, Patrik Nasr, Björn Carlsson, Mattias Ekstedt, Sebastian Ueckert
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 2038-2049 (2023)
Abstract Disease progression in nonalcoholic steatohepatitis (NASH) is highly heterogenous and remains poorly understood. Fibrosis stage is currently the best predictor for development of end‐stage liver disease and mortality. Better understanding
Externí odkaz:
https://doaj.org/article/bf1703e2ce564bf6916f27c82905c8b3
Autor:
Tilda Herrgårdh, Christian Simonsson, Mattias Ekstedt, Peter Lundberg, Karin G. Stenkula, Elin Nyman, Peter Gennemark, Gunnar Cedersund
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-20 (2023)
Abstract Background The increased prevalence of insulin resistance is one of the major health risks in society today. Insulin resistance involves both short-term dynamics, such as altered meal responses, and long-term dynamics, such as the developmen
Externí odkaz:
https://doaj.org/article/513807bc153f4c39b36e53a19c7af91a
Autor:
Christina Gummesson, Stina Alm, Anna Cederborg, Mattias Ekstedt, Jarl Hellman, Hans Hjelmqvist, Magnus Hultin, Katarina Jood, Charlotte Leanderson, Bertil Lindahl, Riitta Möller, Björn Rosengren, Anders Själander, Peter J Svensson, Stefan Särnblad, Alexander Tejera
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background The development of entrustable professional activities (EPAs) as a framework for work-based training and assessment in undergraduate medical education has become popular. EPAs are defined as units of a professional activity requir
Externí odkaz:
https://doaj.org/article/07c499f48ad242069fd55db9f7b911c0
Autor:
Camilla Akbari, Maja Dodd, Per Stål, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Johan Vessby, Fredrik Rorsman, Xiao Zhang, Tongtong Wang, Thomas Jemielita, Gail Fernandes, Samuel S. Engel, Hannes Hagström, Ying Shang
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100915- (2024)
Background & Aims: Long-term studies of the prognosis of NAFLD are scarce. Here, we investigated the risk of major adverse liver outcomes (MALO) in a large cohort of patients with NAFLD. Methods: We conducted a cohort study with data from Swedish uni
Externí odkaz:
https://doaj.org/article/0c0a9f573385433ba987364ed741ecf0
Autor:
Matthew McTeer, Douglas Applegate, Peter Mesenbrink, Vlad Ratziu, Jörn M Schattenberg, Elisabetta Bugianesi, Andreas Geier, Manuel Romero Gomez, Jean-Francois Dufour, Mattias Ekstedt, Sven Francque, Hannele Yki-Jarvinen, Michael Allison, Luca Valenti, Luca Miele, Michael Pavlides, Jeremy Cobbold, Georgios Papatheodoridis, Adriaan G Holleboom, Dina Tiniakos, Clifford Brass, Quentin M Anstee, Paolo Missier, LITMUS Consortium investigators
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0299487 (2024)
AimsMetabolic dysfunction Associated Steatotic Liver Disease (MASLD) outcomes such as MASH (metabolic dysfunction associated steatohepatitis), fibrosis and cirrhosis are ordinarily determined by resource-intensive and invasive biopsies. We aim to sho
Externí odkaz:
https://doaj.org/article/67ecf06493dd4d75bdee07628520f62d
Autor:
Elke Ericson, Linnéa Bergenholm, Anne‐Christine Andréasson, Carly I. Dix, Jane Knöchel, Sara F. Hansson, Richard Lee, Jennifer Schumi, Madeleine Antonsson, Ola Fjellström, Patrik Nasr, Mathias Liljeblad, Björn Carlsson, Stergios Kechagias, Daniel Lindén, Mattias Ekstedt
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2689-2701 (2022)
Abstract In nonalcoholic fatty liver disease (NAFLD) the patatin‐like phospholipase domain‐containing 3 (PNPLA3) rs738409 variant is a contributor. In mice, the Pnpla3 148M variant accumulates on lipid droplets and probably leads to sequestration
Externí odkaz:
https://doaj.org/article/09395c29b57e4f08a41e517a3c5a8290
Autor:
Ángel Herraiz-Adillo, Viktor H. Ahlqvist, Sara Higueras-Fresnillo, Daniel Berglind, Patrik Wennberg, Cecilia Lenander, Bledar Daka, Mattias Ekstedt, Johan Sundström, Francisco B. Ortega, Carl Johan Östgren, Karin Rådholm, Pontus Henriksson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundTo quantify cardiovascular health (CVH), the American Heart Association (AHA) recently launched an updated construct of the “Life's Simple 7” (LS7) score, the “Life's Essential 8” (LE8) score. This study aims to analyse the associat
Externí odkaz:
https://doaj.org/article/40c645b0299445a38caeacb79e069f76
Publikováno v:
JHEP Reports, Vol 5, Iss 3, Pp 100663- (2023)
Background & Aims: Adverse muscle composition (MC) (i.e., low muscle volume and high muscle fat) has previously been linked to poor functional performance and comorbidities in non-alcoholic fatty liver disease (NAFLD). In this study we aimed to inves
Externí odkaz:
https://doaj.org/article/88c89b1762be4e76ba8325ebf9159087