Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mattia Ghirardello"'
Autor:
Beatriz Piniello, Javier Macías-León, Shun Miyazaki, Ana García-García, Ismael Compañón, Mattia Ghirardello, Víctor Taleb, Billy Veloz, Francisco Corzana, Atsushi Miyagawa, Carme Rovira, Ramon Hurtado-Guerrero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Soluble HMW1C-like N-glycosyltransferases (NGTs) catalyze the glycosylation of Asn residues in proteins, a process fundamental for bacterial autoaggregation, adhesion and pathogenicity. However, our understanding of their molecular mechanism
Externí odkaz:
https://doaj.org/article/dadb10d73719446db2e017d884d7e561
Autor:
Beatriz Piniello, Javier Macías-León, Shun Miyazaki, Ana García-García, Ismael Compañón, Mattia Ghirardello, Víctor Taleb, Billy Veloz, Francisco Corzana, Atsushi Miyagawa, Carme Rovira, Ramon Hurtado-Guerrero
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/8cab20f488114b24b1bcebc03e6fa17a
Autor:
Abigail Harland, Xia Liu, Mattia Ghirardello, M. Carmen Galan, Claire M. Perks, Kathreena M. Kurian
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioma stem-like cells (GSCs) were first described as a population which may in part be resistant to traditional chemotherapeutic therapies and responsible for tumour regrowth. Knowledge of the underlying metabolic complexity governing GSC growth and
Externí odkaz:
https://doaj.org/article/343bfe4cdb0d40628831d705a914bc96
Publikováno v:
Nanomaterials, Vol 11, Iss 8, p 1877 (2021)
Antimicrobial resistance is a recognized global challenge. Tools for bacterial detection can combat antimicrobial resistance by facilitating evidence-based antibiotic prescribing, thus avoiding their overprescription, which contributes to the spread
Externí odkaz:
https://doaj.org/article/6b5a01cba51048079c79dcd87f82a6a6
Autor:
Teodoro Garcia-Millan, Javier Ramos-Soriano, Mattia Ghirardello, Robert L. Harniman, Xia Liu, David J. Morgan, Stephen Hughes, Sean A. Davis, Thomas A.A. Oliver, Kathreena M. Kurian, M Carmen Galan
Dual-emission fluorescence probes that provide high sensitivity are key for biomedical diagnostic applications. Non-toxic carbon dots (CDs) are a good alternative to traditional fluorescent probes, however robust and reproducible synthetic strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c9cabe1928b995171eaed1b2ccd85e8
https://doi.org/10.26434/chemrxiv-2023-bvncz
https://doi.org/10.26434/chemrxiv-2023-bvncz
Autor:
Tessa Keenan, Natasha Hatton, Jack Porter, Jean-Baptiste Vendeville, David Wheatley, Mattia Ghirardello, Alice Wahart, Sanaz Ahmadipour, Julia Walton, Carmen Galan, Bruno Linclau, Gavin Miller, Martin Fascione
b-Mannosides are ubiquitous in nature, with diverse roles in many biological processes. Notably, Manb1,4GlcNAc a constituent of the core N-glycan in eukaryotes, was recently identified as a STING immune pathway activator, highlighting its potential f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c51d2446bd02e77f79e6a7b02a7a2d
https://doi.org/10.26434/chemrxiv-2023-3dql5
https://doi.org/10.26434/chemrxiv-2023-3dql5
Publikováno v:
Chemical Society reviews. 51(24)
Cell surface carbohydrates mediate a wide range of carbohydrate-protein interactions key to healthy and disease mechanisms. Many of such interactions are multivalent in nature and in order to study these processes at a molecular level, many glycan-pr
Autor:
Mattia Ghirardello, R. Shyam, M. C. Galan, X. Liu, I. Sittel, Kathreena M Kurian, J. Ramos Soriano, T. Garcia Millan
Publikováno v:
Ghirardello, M, Shyam, R, Liu, X, Garcia-Millan, T, Sittel, I, Ramos-Soriano, J, Kurian, K M & Galan, M C 2022, ' Carbon dot-based fluorescent antibody nanoprobes as brain tumour glioblastoma diagnostics ', Nanoscale Advances, vol. 4, no. 7, pp. 1770-1778 . https://doi.org/10.1039/d2na00060a
The development of efficient and sensitive tools for the detection of brain cancer in patients is of the utmost importance particularly because many of these tumours go undiagnosed until the disease has advanced and when treatment is less effective.
Autor:
Mattia Ghirardello, Maira Costantini, Alessandra Vecchi, Salvatore Pacifico, Daniele Pazzi, Franca Castiglione, Andrea Mele, Alberto Marra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a84467def3ee3d77f2e6a057e5fae8a
http://hdl.handle.net/11311/1212866
http://hdl.handle.net/11311/1212866
Publikováno v:
Ghirardello, M, Zhang, Y-Y, Voglmeir, J & Galan, M C 2022, ' Recent applications of ionic liquid-based tags in glycoscience ', Carbohydrate Research, vol. 520, 108643 . https://doi.org/10.1016/j.carres.2022.108643
The functionalization of glycosides with ionic compounds such as ionic liquids provides enhanced polarity for the labelled glycans thanks to the presence of a permanent positive charge. The chemical derivatisation of glycans with ionic liquids consti