Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Mattia, Bugatti"'
Autor:
Matilde Monti, Giorgia Ferrari, Luisa Gazzurelli, Mattia Bugatti, Fabio Facchetti, William Vermi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-31 (2024)
Abstract Plasmacytoid dendritic cells (pDCs) are multifaceted immune cells executing various innate immunological functions. Their first line of defence consists in type I interferons (I-IFN) production upon nucleic acids sensing through endosomal To
Externí odkaz:
https://doaj.org/article/21418063ec4a404386de06f21aa6706c
Autor:
Matilde Monti, Luisa Benerini Gatta, Mattia Bugatti, Irene Pezzali, Sara Picinoli, Marcello Manfredi, Antonio Lavazza, Virginia Vita Vanella, Veronica De Giorgis, Lucia Zanatta, Francesco Missale, Silvia Lonardi, Benedetta Zanetti, Giovanni Bozzoni, Moris Cadei, Andrea Abate, Barbara Vergani, Piera Balzarini, Simonetta Battocchio, Carla Facco, Mario Turri-Zanoni, Paolo Castelnuovo, Piero Nicolai, Ester Fonsatti, Biagio Eugenio Leone, Emilio Marengo, Sandra Sigala, Roberto Ronca, Michela Perego, Davide Lombardi, William Vermi
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Mucosal Melanomas (MM) are highly aggressive neoplasms arising from mucosal melanocytes. Current treatments offer a limited survival benefit for patients with advanced MM; moreover, the lack of pre-clinical cellular systems has si
Externí odkaz:
https://doaj.org/article/735a9e3b74ed45228ece9b45b07e75d1
Autor:
Matilde Monti, Giorgia Ferrari, Valentina Grosso, Francesco Missale, Mattia Bugatti, Valeria Cancila, Stefania Zini, Agnese Segala, Luca La Via, Francesca Consoli, Matteo Orlandi, Alessandra Valerio, Claudio Tripodo, Marzia Rossato, William Vermi
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionPlasmacytoid dendritic cells (pDCs) infiltrate a large set of human cancers. Interferon alpha (IFN-α) produced by pDCs induces growth arrest and apoptosis in tumor cells and modulates innate and adaptive immune cells involved in anti-can
Externí odkaz:
https://doaj.org/article/d50cd464a3094e938c889963794abc80
Autor:
Federica Maccarinelli, Daniela Coltrini, Silvia Mussi, Mattia Bugatti, Marta Turati, Paola Chiodelli, Arianna Giacomini, Floriana De Cillis, Nadia Cattane, Annamaria Cattaneo, Alessia Ligresti, Michela Asperti, Maura Poli, William Vermi, Marco Presta, Roberto Ronca
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Prostate cancer (PCa) is a leading cause of death in the male population commonly treated with androgen deprivation therapy that often relapses as androgen-independent and aggressive castration-resistant prostate cancer (CRPC). Ferroptosis i
Externí odkaz:
https://doaj.org/article/d2f06106b4a44356b5ea9e86529a1e23
Autor:
Luisa Lorenzi, Torsten Haferlach, Luigi Mori, Matteo Simbeni, Wencke Walter, Piera Balzarini, Manja Meggendorfer, Claudia Döring, Silvia Lonardi, Mattia Bugatti, Claudio Agostinelli, Jay Mehta, Anita Borges, Abbas Agaimy, Ingrid Simonitsch-Klupp, José Cabeçadas, Elias Campo, Stefano Aldo Pileri, Fabio Facchetti, Martin Leo Hansmann, Sylvia Hartmann
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
Standardized treatment options are lacking for patients with unresectable or multifocal follicular dendritic cell sarcoma (FDCS) and disease-related mortality is as high as 20%. Applying whole-genome sequencing (WGS) in one case and whole-exome seque
Externí odkaz:
https://doaj.org/article/7d12e97284a243cf9d77002a8bba07c5
Autor:
Chiara Romani, Luigi Lorini, Anna Bozzola, Eliana Bignotti, Michele Tomasoni, Laura Ardighieri, Mattia Bugatti, Simonetta Battocchio, Antonella Ravaggi, Davide Tomasini, Marco Ravanelli, Cristina Gurizzan, Davide Lombardi, Davide Mattavelli, Stefano Calza, Cesare Piazza, Paolo Bossi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Adenoid cystic carcinoma (ACC) of salivary gland is a slowly growing tumor showing a propensity for delayed recurrence, with decreased survival rates. The identification of poor prognosis patients may help in defining molecular-based targete
Externí odkaz:
https://doaj.org/article/5264e55f9dfa4d33b3204b77d6950bb3
Autor:
Erica Dander, Paola Vinci, Stefania Vetrano, Camilla Recordati, Rocco Piazza, Grazia Fazio, Donatella Bardelli, Mattia Bugatti, Francesca Sozio, Andrea Piontini, Sonia Bonanomi, Luca Bertola, Elena Tassistro, Maria Grazia Valsecchi, Stefano Calza, William Vermi, Andrea Biondi, Annalisa Del Prete, Silvano Sozzani, Giovanna D’Amico
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Gastrointestinal graft-versus-host disease (GvHD) is a major cause of mortality and morbidity following allogeneic bone marrow transplantation (allo-BMT). Chemerin is a chemotactic protein that recruits leukocytes to inflamed tissues by interacting w
Externí odkaz:
https://doaj.org/article/dbecbfc768a34dc292d6255a76e65c83
The prometastatic relevance of tumor‐infiltrating B lymphocytes in laryngeal squamous cell carcinoma
Autor:
Francesco Missale, Mattia Bugatti, Filippo Marchi, Giulio E Mandelli, Maria Bruni, Giulia Palmerini, Matilde Monti, Anna M Bozzola, Giorgio Arena, Luca Guastini, Maurizio Boggio, Giampiero Parrinello, Giorgio Peretti, William Vermi
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 4, Pp n/a-n/a (2023)
Abstract Objectives Laryngeal squamous cell carcinomas (LSCCs) typically have an excellent prognosis for stage I tumors but a significant risk of locoregional and distant recurrence for intermediate to advanced disease. This study will investigate th
Externí odkaz:
https://doaj.org/article/782ac7a0c4d1438bb61bade6b854070f
Autor:
Davide Pradella, Gianluca Deflorian, Alex Pezzotta, Anna Di Matteo, Elisa Belloni, Daniele Campolungo, Andrea Paradisi, Mattia Bugatti, William Vermi, Matteo Campioni, Antonella Chiapparino, Luigi Scietti, Federico Forneris, Costanza Giampietro, Nina Volf, Michael Rehman, Serena Zacchigna, Maria Paola Paronetto, Anna Pistocchi, Anne Eichmann, Patrick Mehlen, Claudia Ghigna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
UNC5B is a Netrin-1 receptor expressed in endothelial cells that in the absence of ligand induces apoptosis. Here the authors identify an UNC5B splicing isoform that is insensitive to the pro-survival ligand Netrin-1 and is required for apoptosis-dep
Externí odkaz:
https://doaj.org/article/bc552c64149c47869cf73be5501499a0
Autor:
Nicoletta Caronni, Giulia Maria Piperno, Francesca Simoncello, Oriana Romano, Simone Vodret, Yuichi Yanagihashi, Regine Dress, Charles-Antoine Dutertre, Mattia Bugatti, Pierre Bourdeley, Annalisa Del Prete, Tiziana Schioppa, Emilia Maria Cristina Mazza, Licio Collavin, Serena Zacchigna, Renato Ostuni, Pierre Guermonprez, William Vermi, Florent Ginhoux, Silvio Bicciato, Shigekatzu Nagata, Federica Benvenuti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Acquisition of dying tumor cell-associated antigens is an essential step for the initiation of anti-tumor immune response by conventional type 1 dendritic cells (cDC1). Here the authors show that the loss of TIM4 expression in lung tumor associated c
Externí odkaz:
https://doaj.org/article/ed313efe49174e4e8c4bd8e169965081