Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Matti Sarvas"'
Autor:
Riitta Lahesmaa, Anu Haveri, Matti Sarvas, Anne Tammiruusu, Mirja Puolakkainen, Juha T. Korhonen
Publikováno v:
Microbial Pathogenesis. 52(3):157-164
A gram-negative obligate intracellular bacterium, Chlamydia pneumoniae, is a common respiratory pathogen. Here, we examined the invasion and attachment of C. pneumoniae K6 into nonphagocytic HL epithelial cell line by manipulating host plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b95396d154d1453615c14482e3360d5
http://juuli.fi/Record/0247691612
http://juuli.fi/Record/0247691612
Autor:
Muukkonen L, Matti Sarvas, Elise Darmon, van Dijl Jm, Albert Bolhuis, Sierd Bron, Hanne-Leena Hyyryläinen, V. P. Kontinen, P. Koski, Marika Vitikainen, Zoltán Prágai
Publikováno v:
Molecular Microbiology. 41:1159-1172
The Gram-positive eubacterium Bacillus subtilis is well known for its high capacity to secrete proteins into the environment. Even though high-level secretion of proteins is an efficient process, it imposes stress on the cell. The present studies wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ddb94be955351d5f38c8cce09637a12
https://doi.org/10.1046/j.1365-2958.2001.02576.x
https://doi.org/10.1046/j.1365-2958.2001.02576.x
Autor:
Marika Gardemeister, Leena Valmu, Haike Antelmann, Vesa P. Kontinen, Anna Ekman, Milla Pietiäinen, Hanne-Leena Hyyryläinen, Sanna Murtomäki-Repo, Tuula Lundén, Matti Sarvas, Michael Hecker
Publikováno v:
Microbiology. 153:2126-2136
The Dlt system modulates the density of negative charge in the cell wall of Gram-positive bacteria by substituting anionic polymers (wall and lipoteichoic acids) with d-alanine. The htrA and htrB genes, regulated by the CssRS two-component system (TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6514ef186e48bd1a6514f6ab1c8aab
https://doi.org/10.1099/mic.0.2007/008680-0
https://doi.org/10.1099/mic.0.2007/008680-0
Autor:
Anne Tammiruusu, Tuula Penttilä, Jenni M. Vuola, Riitta Lahesmaa, Mirja Puolakkainen, Matti Sarvas
Publikováno v:
Vaccine. 25:283-290
Chlamydia pneumoniae is an intracellular pathogen that grows inside a vacuole, referred to as an inclusion. C. pneumoniae possess a type III secretion system (TTSS), which allows them to secrete effector molecules into the inclusion membrane and to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7471f767411b01266e4cb43ed2830b
https://doi.org/10.1016/j.vaccine.2006.07.043
https://doi.org/10.1016/j.vaccine.2006.07.043
Publikováno v:
Journal of Applied Microbiology. 99:363-375
Aims: To explore the potential to enhance secretion of heterologous proteins in Bacillus subtilis by engineering cell factors affecting extracytoplasmic protein folding and degradation. Methods and Results: Bottleneck components affecting the extracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42dfa02c782c11c1d54032a378f01cf
https://doi.org/10.1111/j.1365-2672.2005.02572.x
https://doi.org/10.1111/j.1365-2672.2005.02572.x
Autor:
Mirja Puolakkainen, Jenni M. Vuola, Anne Tammiruusu, Tuula Penttilä, Matti Sarvas, Peter Liljeström, P. Helena Mäkelä
Publikováno v:
Vaccine. 22:3386-3394
Vaccination against Chlamydia pneumoniae would be a beneficial strategy for either preventing or controlling infection by this human respiratory pathogen that also causes persistent infections. In the present study, we used recombinant Semliki Forest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9053d7080719940c16de81fa92f85c
https://doi.org/10.1016/j.vaccine.2004.02.032
https://doi.org/10.1016/j.vaccine.2004.02.032
Autor:
Jaana K. H. Bamford, Dennis H. Bamford, Liisa Laakkonen, Juha T. Huiskonen, Matti Sarvas, Maija Toropainen
Publikováno v:
Virology. 310:267-279
Bacteriophage PRD1 is an icosahedral dsDNA virus with a diameter of 740 Å and an outer protein shell composed of 720 copies of major coat protein P3. Spike complexes at the vertices are composed of a pentameric base (protein P31) and a spike structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001a9251f7ef73b4dcd4c6913bcb947d
https://doi.org/10.1016/s0042-6822(03)00171-5
https://doi.org/10.1016/s0042-6822(03)00171-5
Autor:
Ulla Airaksinen, Mirja Puolakkainen, Eva Wahlström, Tuula Penttilä, Jenni M. Vuola, Matti Sarvas
Publikováno v:
Clinical and Vaccine Immunology. 10:367-375
Due to intracellular growth requirements, large-scale cultures of chlamydiae and purification of its proteins are difficult and laborious. To overcome these problems we produced chlamydial proteins in a heterologous host,Bacillus subtilis, a gram-pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a1a8eef922cb3d2da34d4024e01b50
https://doi.org/10.1128/cdli.10.3.367-375.2003
https://doi.org/10.1128/cdli.10.3.367-375.2003
Autor:
Michael Hecker, Harold Tjalsma, Eva Wahlström, Soile Leskelä, Vesa P. Kontinen, Ulf Gerth, Matti Sarvas, Tiina Pummi
Publikováno v:
Journal of Bacteriology. 184:1010-1018
Identification and characterization of a suppressor mutation, sup-15 , which partially restored secretion in the protein secretion-deficient Bacillus subtilis ecsA26 mutant, led us to discover a novel function of Clp protease. Inactivation of ClpP im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98086c3cbcc50491eca07aabfa95a492
https://doi.org/10.1128/jb.184.4.1010-1018.2002
https://doi.org/10.1128/jb.184.4.1010-1018.2002
Publikováno v:
Applied Microbiology and Biotechnology. 55:326-332
Bacillus subtilis and related Bacillus species are frequently used as hosts for the industrial production of recombinant proteins. In this study the cellular response of B. subtilis to the overproduction of an insoluble heterologous protein was inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fdc5213df739c6c54b56cde16ee92e
https://doi.org/10.1007/s002530000531
https://doi.org/10.1007/s002530000531