Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Matti Kaartinen"'
Autor:
Olli Mäkelä, Matti Kaartinen
Publikováno v:
Immunology today. 6(11)
Publikováno v:
Cytometry. 43:134-142
Background We have previously characterized apoptotic cell death induced in a follicular lymphoma cell line, HF-1, after triggering via the B-cell receptor (BCR) or treatment with Ca2+ Ionophore A23187. We analyzed the kinetics of apoptosis induced b
Publikováno v:
European Journal of Immunology. 25:3263-3269
The functional immunoglobulin (Ig) genes of B lymphocytes undergo somatic mutations during immune responses. These mutations modify the antigen binding site of the immunoglobulins, thereby enhancing the average affinity of the antibodies produced. Th
Publikováno v:
Scandinavian Journal of Immunology. 39:295-300
Variable immunoglobulin heavy-chain regions (VDJ) of two newly established human lymphoma cell lines (HF-1 and HF-4) were sequenced. The most homologous germline VH gene found for both the HF-1 and HF-4 sequences was VH26 of the VH3a (V gene) family
Autor:
Leif C. Andersson, Tommy Nordström, Mine Eray, Hongyan Wu, Sakari Knuutlla, Teppo Tuomikoski, Matti Kaartinen
Publikováno v:
International Immunology. 6:1817-1827
We have established three lymphoma cell lines, HF-1 from one follicular lymphoma (FL) patient, and HF-4 and HF-9 from another. All cell lines carry the characteristic t(14;18) chromosomal translocation and express constitutively the bcl-2 gene produc
Publikováno v:
Molecular Immunology. 29:1357-1362
The early primary anti-phenyloxazolone antibodies of 12 mouse strains were studied by determining proportions of two defined subsets id495 (the classical phOx idiotype) and id350. Id495-positive antibodies bear an H chain encoded by V H Oxl gene (fam
Publikováno v:
European Journal of Immunology. 21:2863-2869
One pair of V genes (V kappa 45.1 and V11) code for a great portion of phenyloxazolone (anti-phOx) antibodies in 10 strains of mice. This combination replaces the first-known major combination VHOx1-V kappa Ox1 in some strains, and is important in mo
Publikováno v:
Systematic and Applied Microbiology. 14:270-274
Summary Partial 16S rRNA sequences of seven Helicobacter pylori strains from three different continents were compared. High homogeneity (99.5%–100%) of 16S rRNA between H. pylori strains was demonstrated, when a 397 nucleotides long stretch of RNA
An active single-chain antibody containing a cellulase linker domain is secreted by Escherichia coli
Autor:
Tiina Immonen, Marja-Leena Laukkanen, Liisa Vanne, Tuula T. Teeri, Kaija Alfthan, Kristiina Takkinen, Matti Kaartinen, Dorothea Sizmann, Jonathan Knowles
Publikováno v:
Takkinen, K, Laukkanen, M-L, Sizmann, D, Alfthan, K, Immonen, T, Vanne, L, Kaartinen, M, Knowles, J & Teeri, T 1991, ' An active single-chain antibody containing a cellulase linker domain is secreted by Escherichia coli ', Protein Engineering, vol. 4, no. 7, pp. 837-841 . https://doi.org/10.1093/protein/4.7.837
Single-chain antibodies consist of the variable, antigen-binding domains of antibodies joined to a continuous polypeptide by genetically engineered peptide linkers. We have used the flexible interdomain linker region of a fungal cellulase to link tog
Autor:
Mine Eray, Matti Kaartinen, Guillermo Eli Liwszyc, Aino Paasinen-Sohns, Anders Ståhls, Leif C. Andersson
Publikováno v:
International immunology. 10(10)
Cross-linking of B cell antigen receptor (sIg) elicits different biological responses, including cell activation, proliferation, differentiation, anergy and cell death depending on the maturational stage of the cell. We established the tumor cell lin