Association of white blood cell count with one-year mortality after cardiac arrest

Autor: Asser M.J. Seppä, Markus B. Skrifvars, Heidi Vuopio, Rahul Raj, Matti Reinikainen, Pirkka T. Pekkarinen

Publikováno v: Resuscitation Plus, Vol 20, Iss , Pp 100816- (2024)

Introduction: Post-resuscitation care of cardiac arrest patients may be complicated by systemic inflammation elicited in response to whole-body ischaemia–reperfusion injury. We assessed the association between early WBC with one-year mortality in a

Externí odkaz: https://doaj.org/article/b5d32fcf85d64d43ab71088be6822bd7

Interactions in the 2×2×2 factorial randomised clinical STEPCARE trial and the potential effects on conclusions: a protocol for a simulation study

Autor: Markus Harboe Olsen, Aksel Karl Georg Jensen, Josef Dankiewicz, Markus B. Skrifvars, Matti Reinikainen, Marjaana Tiainen, Manoj Saxena, Anders Aneman, Christian Gluud, Susann Ullén, Niklas Nielsen, Janus Christian Jakobsen

Publikováno v: Trials, Vol 23, Iss 1, Pp 1-7 (2022)

Abstract Background Randomised clinical trials with a factorial design may assess the effects of multiple interventions in the same population. Factorial trials are carried out under the assumption that the trial interventions have no interactions on

Externí odkaz: https://doaj.org/article/efefea2a1b70488c8ad19f6d4f18eeee

Premorbid functional status as an outcome predictor in intensive care patients aged over 85 years

Autor: Laura Pietiläinen, Minna Bäcklund, Johanna Hästbacka, Matti Reinikainen

Publikováno v: BMC Geriatrics, Vol 22, Iss 1, Pp 1-9 (2022)

Abstract Background Poor premorbid functional status (PFS) is associated with mortality after intensive care unit (ICU) admission in patients aged 80 years or older. In the subgroup of very old ICU patients, the ability to recover from critical illne

Externí odkaz: https://doaj.org/article/5da245dedd194549b61ac8be42bf549d

Serum fibroblast growth factor 21 levels after out of hospital cardiac arrest are associated with neurological outcome

Autor: Pirkka T. Pekkarinen, Markus B. Skrifvars, Ville Lievonen, Pekka Jakkula, Laura Albrecht, Pekka Loisa, Marjaana Tiainen, Ville Pettilä, Matti Reinikainen, Johanna Hästbacka

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Fibroblast growth factor (FGF) 21 is a marker associated with mitochondrial and cellular stress. Cardiac arrest causes mitochondrial stress, and we tested if FGF 21 would reflect the severity of hypoxia-reperfusion injury after cardiac arres

Externí odkaz: https://doaj.org/article/832b3361350a4e4986a3f24aca74bb2f

Essential Emergency and Critical Care: a consensus among global clinical experts

Autor: Samuel Akech, Mike English, Thomas G Weiser, Adam D Laytin, Niranjan Kissoon, Jaran Eriksen, Lovenish Bains, Fred Bulamba, Claudia Hanson, Maria Jirwe, Jolene Moore, Mpoki Ulisubisya, Vincent Ioos, Kent Doi, Lee A Wallis, Tom Bashford, Kapil Dev Soni, Nobhojit Roy, Franco Diaz, Mulinda Nyirenda, Nicholas Risko, Hendry R Sawe, Jacob McKnight, Alexandra Wharton-Smith, Jamie Rylance, Monty Khajanchi, Gavin Wooldridge, Emmanuel Fru Nsutebu, Lisa Kurland, Peter Baker, John C Marshall, Kathryn Rowan, Usha Lalla, Balasubramanian Venkatesh, Cornelius Sendagire, Neill KJ Adhikari, Tim Baker, Brian Rice, Josephine Langton, Elisabeth Riviello, Fiona Muttalib, Francis Mupeta, Jacquie Oliwa, Stefan Swartling Peterson, Andrew G Smith, Lorna Guinness, Megan Cox, Wim Van Damme, John Kellett, Elizabeth M Molyneux, Richard Venn, Andrea B Pembe, Mervyn Mer, Ignacio Martin-Loeches, Raymond Towey, Lina Zhang, Blaise Pascal, Hiral A Shah, Carl Otto Schell, Karima Khalid, Paul D Sonenthal, Alex Sanga, Raphael K. Kayambankadzanja, Adam Asghar, Adrian J Holloway, Ahmed Rhassane El Adib, Alexia Michaelides, Alvaro Coronado Munoz, Amos Muzuka, Analía Fernández, Andreas Wellhagen, Anita Gadgil, Anna Hvarfner, Anuja Abayadeera, Asya Agulnik, Aurélie Godard, Bargo Mahamat Yousif, Bhakti Sarang Ben Morton, Bharath Kumar, Tirupakuzhi Vijayaraghavan, Bobby King, C Louise Thwaites, Chian Wern Tai, Christian Owoo, Dan Brun Petersen, Daniel Tatay, David Lee Skinner, Denis Kinyua, Dhruva Ghosh, Diptesh Aryal, Donald Mlombwa, Duyen Thi, Hanh Bui, Edwin R Lugazia, Ellena Heyns, Erika Montalvo, Ernesto Gerardo Moreno, Esther Banda Kanyangira, Furaha Nzanzu, Gibonce Mwakisambwe, Guy A Richards, Hala Ammar, Halinder S Mangat, Hasanein H Ghali, Hoi Ping Shum, Ibrahim Salim Abdullahi, Ingrid T von der Osten, James S Lee, Jane Kasozi Namagga, Jasmine Armour-Marshall, John Z Metcalfe, Jonas Blixt, Juan Gutierrez Mejia, Juan Ignacio Silesky-Jiménez, Karl Martin Kohne, Kazuhiro Yokobatake, Kristina E. Rudd, Kwame Asante Akuamoah-Boateng, Lars Irestedt, Lia I Losonczy, Margaret Nyaika, Markus Castegren, Matthew Loftus, Matti Reinikainen, Michael Jaung, Michael S Lipnick, Miklos Lipcey, Märit Amanda Halmin, Naman Shah, Natalie L Cobb, Nathan D Nielsen, Neville Vlok, Ntogwiachu Daniel Kobuh, Oscar Fernández Rostello, Patricia Duque, Paul Patrick Mwasapi, Petronella Bjurling-Sjöberg, Piedad Sarmiento, Pryanka Relan, Rebecca Silvers, Rehema Mlay, Rich Branson, Richard J Wang, Richard Kojan, Richard Peter Von Rahden, Rob Mac Sweeney, Rodrigo Genaro Arduini, Rodwell Gundo, Ruyumbu Sixtus, Samson Kwazizira Mndolo, Shada A. Rouhani, Siriel Nanzia Massawe, Steven A Webb, Sunkaru Touray, Susana Guido, Teresa Kortz, Theodoros Aslanidis, Traci A Wolbrink, V Theodore Barnett, Vijay Christopher Kannan, Waleed S Eldebsy, Wangari Waweru-Siika, Wezzie Kumwenda Mwafulirwa, William Obeng, Yasein Omer, Zione Banda

Publikováno v: BMJ Global Health, Vol 6, Iss 9 (2021)

Background Globally, critical illness results in millions of deaths every year. Although many of these deaths are potentially preventable, the basic, life-saving care of critically ill patients are often overlooked in health systems. Essential Emerge

Externí odkaz: https://doaj.org/article/de5537511f7749b889a3e7d97b1f863c