Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Matti, Juhola"'
Autor:
Matti Juhola, Matti Säily, Heikki Järvinen, Annette Gylling, Markku Aarnio, Jukka-Pekka Mecklin, Päivi Peltomäki
Publikováno v:
Familial Cancer
Increased risk for urological tumors has been observed in mutation carriers with Lynch syndrome (LS). In this study, we evaluated the clinical features of uroepithelial (bladder and ureter) and kidney cancers in 974 Finnish mutation carriers. Altoget
Autor:
Taina T. Nieminen, Päivi Peltomäki, M. Aarnio, Mecklin Jp, Annette Gylling, Kyösti Nuorva, Heikki Järvinen, Emmi I. Joensuu, Wael M. Abdel-Rahman, Matti Juhola
Publikováno v:
Carcinogenesis. 29:1351-1359
Hereditary non-polyposis colorectal carcinoma (Lynch syndrome) is among the most common hereditary cancers in man and a model of cancers arising through deficient DNA mismatch repair (MMR). Lynch syndrome patients are predisposed to different cancers
Autor:
Matti Juhola, Kirsi Hämäläinen, Sari M. Sillanpää, Seppo Saarikoski, Maarit Anttila, Veli-Matti Kosma, Kirsi A. Suhonen
Publikováno v:
European Journal of Cancer. 43:1300-1307
The aim of the present study was to clarify prognostic role of angiogenesis in epithelial ovarian cancer.Quantification of angiogenesis was performed by the Chalkley method after immunostaining of 175 epithelial ovarian cancer specimens with an antib
Autor:
Jari Kellokoski, Risto Pirinen, Jukka Virtaniemi, K M Ropponen, Veli-Matti Kosma, Matti Pukkila, Matti Juhola, Ari Kosunen, Reijo Sironen, Risto T. Johansson, Eero J. Kumpulainen, Juhani Nuutinen
Publikováno v:
Oral Oncology. 43:51-59
We investigated the expression of CD44 and MMP-9 in primary oral squamous cell carcinoma (OSCC) and evaluated their association with each other and clinicopathological factors as well as their prognostic value during long term follow up. Histological
Autor:
Sari M. Sillanpää, K M Ropponen, Veli-Matti Kosma, Seppo Saarikoski, Maarit Anttila, Kirsi Voutilainen, Matti Juhola
Publikováno v:
Journal of Clinical Pathology. 59:460-467
Objective: To clarify the prognostic role of E-cadherin and β- and γ-catenins, and their relation to CD44 in epithelial ovarian carcinoma. Methods: The expression of E-cadherin and β- and γ-catenins was analysed immunohistochemically in 305 prima
Autor:
Hanna Tuhkanen, Veli-Matti Kosma, Matti Juhola, Vesa Kataja, Arto Mannermaa, Seppo Heinonen, Seppo Helisalmi, Maarit Anttila
Publikováno v:
International Journal of Cancer. 119:1345-1353
Stromal cells are an active and integral part of epithelial neoplasms. We have previously observed allelic imbalance on chromosome 3p21 in both stromal and epithelial cells of ovarian tumors. This study was designed to explore gene dosage alterations
Autor:
Maija Ht Kiuru, Charis Eng, Heikki Järvinen, Eero Pukkala, Andrzej Januszewicz, Riitta Herva, Mary Buchta, Mariola Pęczkowska, Matti Juhola, Lauri A. Aaltonen, Nina N. Nupponen, Carl Morrison, Rainer Lehtonen, Sarah R. McWhinney, Sanna K. Virta, Jukka-Pekka Mecklin, Sakari Vanharanta, Hartmut P. H. Neumann
Publikováno v:
University of Helsinki
Hereditary paraganglioma syndrome has recently been shown to be caused by germline heterozygous mutations in three (SDHB, SDHC, and SDHD) of the four genes that encode mitochondrial succinate dehydrogenase. Extraparaganglial component neoplasias have
Autor:
Seppo Heinonen, Veli-Matti Kosma, Markku Tammi, Arja Kuronen, Matti Juhola, Raija Tammi, Seppo Ylä-Herttuala, Hanna Tuhkanen, Maarit Anttila, Arto Mannermaa
Publikováno v:
International Journal of Cancer. 109:247-252
Stromal accumulation of hyaluronan in epithelial ovarian cancers is an independent predictor of tumor spreading and unfavorable outcome of the disease. We started to screen for chromosomal causes of this accumulation by studying deletions in 3p21.3,
Autor:
Matti Juhola, Markku Voutilainen, Ilkka Kunnamo, Martti Färkkilä, Timo Mäntynen, Jukka-Pekka Mecklin
Publikováno v:
The American Journal of Gastroenterology. 97:2524-2529
Less than half of patients with gastroesophageal reflux disease (GERD) have endoscopic erosive esophagitis (endoscopy positive GERD). Symptomatic GERD and Barrett's esophagus (BE), however, are risk factors for esophageal and gastric cardia adenocarc
Publikováno v:
Scandinavian Journal of Gastroenterology. 36:817-821
Non-steroidal anti-inflammatory drug and aspirin (here collectively called NSAIDs) use is the second most common aetiologic factor for peptic ulcer disease and a major factor for peptic ulcer complications. The role of NSAIDs in the pathogenesis of u