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pro vyhledávání: '"Matthijs W. van Hoogdalem"'
Autor:
Matthijs W. van Hoogdalem, Ryota Tanaka, Khaled Abduljalil, Trevor N. Johnson, Scott L. Wexelblatt, Henry T. Akinbi, Alexander A. Vinks, Tomoyuki Mizuno
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 375 (2024)
Buprenorphine readily crosses the placenta, and with greater prenatal exposure, neonatal opioid withdrawal syndrome (NOWS) likely grows more severe. Current dosing strategies can be further improved by tailoring doses to expected NOWS severity. To al
Externí odkaz:
https://doaj.org/article/f4fb827a797440a68bc781f557d22126
Autor:
Henry T. Akinbi, Alexander A. Vinks, Scott L. Wexelblatt, Matthijs W. van Hoogdalem, Brooks T. McPhail, Tomoyuki Mizuno, David Hahn
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 17:87-103
Neonatal opioid withdrawal syndrome (NOWS) often arises in infants born to mothers who used opioids during pregnancy. Morphine, methadone, and buprenorphine are the most common first-line treatments, whereas clonidine and phenobarbital are generally
Autor:
Tsuyoshi Fukuda, Matthijs W. van Hoogdalem, Parinda A. Mehta, Chie Emoto, Alexander A. Vinks, Tomoyuki Mizuno
Publikováno v:
British Journal of Clinical Pharmacology
Aims Fanconi anaemia (FA) is a rare disorder characterized by progressive bone marrow failure that requires haematopoietic cell transplantation (HCT). Busulfan is used in conditioning regimens prior to HCT. Doses used in non‐FA patients cause life
Autor:
Scott L. Wexelblatt, Henry T. Akinbi, Alexander A. Vinks, Tomoyuki Mizuno, Matthijs W. van Hoogdalem
Publikováno v:
Pharmacologytherapeutics. 234
Physiologically-based pharmacokinetic (PBPK) modeling has emerged as a useful tool to study pharmacokinetics (PK) in special populations, such as pregnant women, fetuses, and newborns, where practical hurdles severely limit the study of drug behavior
Autor:
Uwe Christians, Laura P. Ward, Suyog Kamatkar, Trevor N. Johnson, Henry T. Akinbi, Alexander A. Vinks, Tomoyuki Mizuno, Scott L. Wexelblatt, Matthijs W. van Hoogdalem, Brooks T. McPhail
Publikováno v:
Clin Pharmacol Ther
Neonatal opioid withdrawal syndrome (NOWS) is a major public health concern whose incidence has paralleled the opioid epidemic in the United States. Sublingual buprenorphine is an emerging treatment for NOWS, but given concerns about long-term advers