Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Matthijs R.H. Kooistra"'
Autor:
Matthijs R.H. Kooistra, Holger Rehmann, Fried J. T. Zwartkruis, Leo S. Price, Jun Zhao, Johannes L. Bos, Kees Jalink, Martijn Gloerich, Marjolein J. Vliem, Bas Ponsioen, Zhongchun Zhang, Laila Ritsma
Publikováno v:
Molecular and Cellular Biology. 30:5421-5431
Epac1 is a guanine nucleotide exchange factor for the small G protein Rap and is involved in membrane-localized processes such as integrin-mediated cell adhesion and cell-cell junction formation. Cyclic AMP (cAMP) directly activates Epac1 by release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc3953941e9d9874abd36c85074f239
https://doi.org/10.1128/mcb.00463-10
https://doi.org/10.1128/mcb.00463-10
Autor:
Judith Klumperman, Nadia Dubé, Johannes L. Bos, Marjolein J. Vliem, Willem-Jan Pannekoek, Viola Oorschot, Holger Rehmann, Matthijs R.H. Kooistra
Publikováno v:
Cellular Signalling. 20:1608-1615
The small G-protein Rap1 is a critical regulator of cell–cell contacts and is activated by the remodeling of adherens junctions. Here we identify the Rap1 guanine nucleotide exchange factor PDZ-GEF2 as an upstream activator of Rap1 required for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2a94511fa6a9ed915d11a1b5b315e0
https://doi.org/10.1016/j.cellsig.2008.05.006
https://doi.org/10.1016/j.cellsig.2008.05.006
PKA and Epac1 regulate endothelial integrity and migration through parallel and independent pathways
Autor:
Peter L. Hordijk, Magdalena J. Lorenowicz, Johannes L. Bos, Matthijs R.H. Kooistra, Mar Fernandez-Borja
Publikováno v:
European journal of cell biology, 87(10), 779-792. Urban und Fischer Verlag GmbH und Co. KG
European Journal of Cell Biology, 87(10), 779-792. Urban und Fischer Verlag GmbH und Co. KG
Lorenowicz, M J, Fernandez-Borja, M, Kooistra, M R H, Bos, J L & Hordijk, P L 2008, ' PKA and Epac1 regulate endothelial integrity and migration through parallel and independent pathways ', European Journal of Cell Biology, vol. 87, no. 10, pp. 779-792 . https://doi.org/10.1016/j.ejcb.2008.05.004
European Journal of Cell Biology, 87(10), 779-792. Urban und Fischer Verlag GmbH und Co. KG
Lorenowicz, M J, Fernandez-Borja, M, Kooistra, M R H, Bos, J L & Hordijk, P L 2008, ' PKA and Epac1 regulate endothelial integrity and migration through parallel and independent pathways ', European Journal of Cell Biology, vol. 87, no. 10, pp. 779-792 . https://doi.org/10.1016/j.ejcb.2008.05.004
The vascular endothelium provides a semi-permeable barrier, which restricts the passage Of fluid, macromolecules and cells to the surrounding tissues. Cyclic AMP promotes endothelial barrier function and protects the endothelium against pro-inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802ccff3743d0d268febaa16d77671be
https://doi.org/10.1016/j.ejcb.2008.05.004
https://doi.org/10.1016/j.ejcb.2008.05.004
Publikováno v:
FEBS Letters. 579:4966-4972
We have previously shown that Rap1 as well as its guanine nucleotide exchange factor Epac1 increases cell–cell junction formation. Here, we show that activation of Epac1 with the exchange protein directly activated by cAMP (Epac)-specific cAMP anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd09b25d0c604a12b6c80016c243c3ec
https://doi.org/10.1016/j.febslet.2005.07.080
https://doi.org/10.1016/j.febslet.2005.07.080
Publikováno v:
Journal of cell science. 120(Pt 1)
Rap1 is a Ras-like small GTPase that is activated by many extracellular stimuli and strongly implicated in the control of integrin-mediated cell adhesion. Recent evidence indicates that Rap1 also plays a key role in formation of cadherin-based cell-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a215a1c83035d5e758ddb700261e7d56
https://pubmed.ncbi.nlm.nih.gov/17182900
https://pubmed.ncbi.nlm.nih.gov/17182900
Autor:
Willem-Jan Pannekoek, Frank Schwede, Bas Ponsioen, Hans-Gottfried Genieser, Marjolein J. Vliem, Kees Jalink, Matthijs R.H. Kooistra, Holger Rehmann, Johannes L. Bos, Jurgen Riedl
Publikováno v:
ChemBioChem. 9:2017-2017
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf972465b07fc56729812d9ccd09b0a1
https://doi.org/10.1002/cbic.200890049
https://doi.org/10.1002/cbic.200890049
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (4):790-796
Rap proteins are Ras-like small GTP-binding proteins that amongst others are involved in the control of cell–cell and cell–matrix adhesion. Several Rap guanine nucleotide exchange factors (RapGEFs) function to activate Rap. These multi-domain pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78309c8b3226a22ea237758c8920c8d9