Zobrazeno 1 - 10
of 914
pro vyhledávání: '"Matthijs, K."'
Autor:
Vera H. W. de Wit-Verheggen, Vera B. Schrauwen-Hinderling, Kim Brouwers, Johanna A. Jörgensen, Gert Schaart, Anne Gemmink, Emmani B. M. Nascimento, Matthijs K. C. Hesselink, Joachim E. Wildberger, Patrique Segers, David Montaigne, Bart Staels, Patrick Schrauwen, Lucas Lindeboom, Joris Hoeks, Tineke van de Weijer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Cardiac energy status, measured as phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio with 31P-Magnetic Resonance Spectroscopy (31P-MRS) in vivo, is a prognostic factor in heart failure and is lowered in cardiometabolic disease. It has
Externí odkaz:
https://doaj.org/article/37b93e8a37d543e9a681f2a0a9782dad
Akademický článek
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Autor:
Sten M. M. van Beek, Yvonne M. H. Bruls, Froukje Vanweert, Ciarán E. Fealy, Niels J. Connell, Gert Schaart, Esther Moonen-Kornips, Johanna A. Jörgensen, Frédéric M. Vaz, Ellen T. H. C. Smeets, Peter J. Joris, Anne Gemmink, Riekelt H. Houtkooper, Matthijs K. C. Hesselink, Tore Bengtsson, Bas Havekes, Patrick Schrauwen, Joris Hoeks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
β2-agonist treatment improves skeletal muscle glucose uptake and whole-body glucose homeostasis in rodents. Here the authors report that two-weeks of treatment with the β2-agonist clenbuterol improves insulin-stimulated glucose disposal in healthy
Externí odkaz:
https://doaj.org/article/c70a9895a6d34e0086372025f6878383
Autor:
Rodrigo Mancilla, Diego Pava‐Mejia, Nynke vanPolanen, Vera deWit, Maaike Bergman, Lotte Grevendonk, Johanna Jorgensen, Esther Kornips, Joris Hoeks, Matthijs K. C. Hesselink, Vera B. Schrauwen‐Hinderling
Publikováno v:
Physiological Reports, Vol 11, Iss 12, Pp n/a-n/a (2023)
Abstract Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess skeletal muscle mitochondrial capacity, we tested how well different invasive and noninva
Externí odkaz:
https://doaj.org/article/e51d1203343b480098a2feb69c51dec1
Autor:
Froukje Vanweert, Michael Neinast, Edmundo Erazo Tapia, Tineke van de Weijer, Joris Hoeks, Vera B. Schrauwen-Hinderling, Megan C. Blair, Marc R. Bornstein, Matthijs K. C. Hesselink, Patrick Schrauwen, Zoltan Arany, Esther Phielix
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Evidence from preclinical models suggest that lowering levels of branched chain amino acids (BCAA) improves glucose metabolism. Here the authors report that NaPB, an accelerator of BCAA catabolism, improves peripheral insulin sensitivity in patients
Externí odkaz:
https://doaj.org/article/13e10d35d6bc4308a78288bcc1294944
Autor:
Louise Y. Takeshita, Peter K. Davidsen, John M. Herbert, Philipp Antczak, Matthijs K. C. Hesselink, Patrick Schrauwen, S. John Weisnagel, Jeremy M. Robbins, Robert E. Gerszten, Sujoy Ghosh, Mark A. Sarzynski, Claude Bouchard, Francesco Falciani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Despite good adherence to supervised endurance exercise training (EET), some individuals experience no or little improvement in peripheral insulin sensitivity. The genetic and molecular mechanisms underlying this phenomenon are currently not
Externí odkaz:
https://doaj.org/article/9a3774b2c4754f49983653dd5d84465b
Autor:
Jordi P. D. Kleinloog, Ronald P. Mensink, Jos op’t. Roodt, Dick H. J. Thijssen, Matthijs K. C. Hesselink, Peter J. Joris
Publikováno v:
Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)
Abstract It is well‐known that aerobic exercise training beneficially affects endothelial function as measured by brachial artery flow‐mediated vasodilation (FMD). This trial with older sedentary overweight and obese men, therefore, examined the
Externí odkaz:
https://doaj.org/article/484a271a78c241fbafd3ed0d3d7e03ca
Autor:
Carlijn M. E. Remie, Michiel P. B. Moonen, Kay H. M. Roumans, Emmani B. M. Nascimento, Anne Gemmink, Bas Havekes, Gert Schaart, Esther Kornips, Peter J. Joris, Vera B. Schrauwen-Hinderling, Joris Hoeks, Sander Kersten, Matthijs K. C. Hesselink, Esther Phielix, Wouter D. van Marken Lichtenbelt, Patrick Schrauwen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Cold acclimation has been shown to have beneficial metabolic effects, including improved insulin sensitivity in patients with type 2 diabetes. Here the authors show that a mild cold acclimation regiment during which overt shivering was prevented did
Externí odkaz:
https://doaj.org/article/1c9d9177ddf8413ba3d5b7a5b26199f5
Autor:
Marlies de Ligt, Matthijs K. C. Hesselink, Johanna Jorgensen, Nicole Hoebers, Ellen E. Blaak, Gijs H. Goossens
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 408-411 (2021)
Angiotensin converting enzyme-2 (ACE2) is the cell-surface receptor enabling cellular entry of SARS-CoV-2. ACE2 is highly expressed in adipose tissue (AT), rendering AT a potential SARS-CoV-2 reservoir contributing to massive viral spread in COVID-19
Externí odkaz:
https://doaj.org/article/6200abf8734840a1b850c272808e07f8
Akademický článek
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