Evolution and Potential Subfunctionalization of Duplicated fms-Related Class III Receptor Tyrosine Kinase flt3s and Their Ligands in the Allotetraploid Xenopus laevis

Autor: Matthieu Paiola, Siyuan Ma, Jacques Robert

Publikováno v: The Journal of Immunology. 209:960-969

The fms-related tyrosine kinase 3 (Flt3) and its ligand (Flt3lg) are important regulators of hematopoiesis and dendritic cell (DC) homeostasis with unsettled coevolution. Gene synteny and deduced amino acid sequence analyses identified conserved flt3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6170326420711c74b7e3d8a0a20f1eaa
https://doi.org/10.4049/jimmunol.2200201

Amphibians as a model to study the role of immune cell heterogeneity in host and mycobacterial interactions

Autor: Matthieu Paiola, Dionysia Dimitrakopoulou, Martin S. Pavelka, Jacques Robert

Publikováno v: Developmental & Comparative Immunology. 139:104594

Mycobacterial infections represent major concerns for aquatic and terrestrial vertebrates including humans. Although our current knowledge is mostly restricted to Mycobacterium tuberculosis and mammalian host interactions, increasing evidence suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241a10c6212040f0f7b83a8a63e73a7a
https://doi.org/10.1016/j.dci.2022.104594

The influence of 17β-oestradiol on lymphopoiesis and immune system ontogenesis in juvenile sea bass, Dicentrarchus labrax

Autor: Matthieu Paiola, Catarina Moreira, Thomas Knigge, Tiphaine Monsinjon, Ariadna Sitjà-Bobadilla, Aurélie Duflot, Patrícia Pinto, Inmaculada Varó

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Developmental & Comparative Immunology
Digital.CSIC. Repositorio Institucional del CSIC
instname

The female sex steroid 17β-oestradiol (E2) is involved in the regulation of numerous physiological functions, including the immune system development and performance. The role of oestrogens during ontogenesis is, however, not well studied. In rodent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50393a3edcf73a095a4cec1f21ec1aae

Developing Tadpole Xenopus laevis as a Comparative Animal Model to Study Mycobacterium abscessus Pathogenicity

Autor: Michael Cynamon, Dionysia Dimitrakopoulou, Jacques Robert, Matthieu Paiola, Carolyn M. Shoen, Arianna Lopez, Martin S. Pavelka

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 806, p 806 (2021)

Mycobacterium abscessus (Mab) is an emerging, nontuberculosis mycobacterium (NTM) that infects humans. Mab has two morphotypes, smooth (S) and rough (R), related to the production of glycopeptidolipid (GPL), that differ in pathogenesis. To further un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dc1c98ec314ac9abe1944e4b087faa

Flt3 and its ligand as an ancient regulators of dendritic cells: evidence in the amphibian Xenopus laevis

Autor: Matthieu Paiola, Sobhan Roy, Siyuan Ma, Charkira Patrick, Marin Pavelka, Erin J. Adams, Jacques Robert

Publikováno v: The Journal of Immunology. 208:124.11-124.11

The evolution of hematopoietic-derived dendritic cells that are so critical for T cell activation is still poorely understood. In mammals, fms related tyrosine kinase 3 (Flt3) and its ligand (Flt3lg) are important regulator of dendritic cell homeosta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba2ac7844f929d02f075e91632c5086b
https://doi.org/10.4049/jimmunol.208.supp.124.11