Multidimensional scaling reveals the main evolutionary pathways of class A G-protein-coupled receptors.

Autor: Julien Pelé, Hervé Abdi, Matthieu Moreau, David Thybert, Marie Chabbert

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e19094 (2011)

Class A G-protein-coupled receptors (GPCRs) constitute the largest family of transmembrane receptors in the human genome. Understanding the mechanisms which drove the evolution of such a large family would help understand the specificity of each GPCR

Externí odkaz: https://doaj.org/article/7ead42457f694041a3b5312a08fc9bb6

Implementation of volumetric-modulated arc therapy for locally advanced breast cancer patients: Dosimetric comparison with deliverability consideration of planning techniques and predictions of patient-specific QA results via supervised machine learning

Autor: Caroline Noblet, Marie Duthy, Frédéric Coste, Marie Saliou, Benoît Samain, Franck Drouet, Thomas Papazyan, Matthieu Moreau

Publikováno v: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 96

The aim of this study was to implement a clinically deliverable VMAT planning technique dedicated to advanced breast cancer, and to predict failed QA using a machine learning (ML) model to optimize the QA workload.For three planning methods (2A: 2-pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a952d4b06d4848c892fcea7a9b1f3500
https://pubmed.ncbi.nlm.nih.gov/35202917

Comparative analysis of sequence covariation methods to mine evolutionary hubs: Examples from selected GPCR families

Autor: Matthieu Moreau, Patrice Rodien, Hélène Castel, Hervé Abdi, Marie Chabbert, Julien Pelé

Publikováno v: Proteins: Structure, Function, and Bioinformatics. 82:2141-2156

Covariation between positions in a multiple sequence alignment may reflect structural, functional, and/or phylogenetic constraints and can be analyzed by a wide variety of methods. We explored several of these methods for their ability to identify co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8c101da1a6f1aa4acaa56653b4127af
https://doi.org/10.1002/prot.24570

Detector Modeling in PET List-Mode Reconstruction: Comparison Between Pre-calculated and On-the-Fly Computed System Matrices

Autor: Olivier Strauss, Julien Bert, Thomas Carlier, Dimitris Visvikis, Awen Autret, Matthieu Moreau

Publikováno v: IEEE Nuclear Science Symposium and Medical Imaging Conference
NSS/MIC: Nuclear Science Symposium and Medical Imaging Conference
NSS/MIC: Nuclear Science Symposium and Medical Imaging Conference, Oct 2015, San Diego, United States. ⟨10.1109/NSSMIC.2015.7582100⟩
HAL
Society of Nuclear Medicine and Molecular Imaging Annual Meeting
Society of Nuclear Medicine and Molecular Imaging Annual Meeting, 2015, Baltimore, United States

International audience; In List-mode PET iterative image reconstruction two major approaches exist in order to model the detector response. The detector response can be measured or estimated before the reconstruction and stored in a matrix. This appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0941c545b2c2fe3fa7d05afba0f65ae0
https://hal.archives-ouvertes.fr/hal-01888938

Fully 3D tomographic reconstruction by Monte Carlo simulation of the system matrix in preclinical PET with iodine 124

Autor: Matthieu, MOREAU

Publikováno v: Physique [physics]. Faculté de Médecine et des Techniques Médicales-Nantes, 2014. Français. ⟨NNT : ⟩
Physique [physics]. Faculté de Médecine et des Techniques Médicales-Nantes, 2014. Français

Immuno-PET imaging can be used to assess the pharmacokinetic in radioimmunotherapy. When using iodine- 124, PET quantitative imaging is limited by physics-based degrading factors within the detection system and the object, such as the long positron r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c1732dfdc54b498091b8df5f812006dd
https://hal.science/tel-01122928