Comprehensive structural assignment of glycosaminoglycan oligo- and polysaccharides by protein nanopore

Autor: Parisa Bayat, Charlotte Rambaud, Bernard Priem, Matthieu Bourderioux, Mélanie Bilong, Salomé Poyer, Manuela Pastoriza-Gallego, Abdelghani Oukhaled, Jérôme Mathé, Régis Daniel

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Glycosaminoglycans (GAGs) are highly anionic functional polysaccharides with subtle structural variations that are very difficult to differentiate. Here the authors demonstrate proof-of-concept single-molecule detection by nanopore, taking a first st

Externí odkaz: https://doaj.org/article/18b1c60b9c0f4531816fb57c2e5cef8d

Comparative proteomics of respiratory exosomes in cystic fibrosis, primary ciliary dyskinesia and asthma

Autor: Cerina Chhuon, Matthieu Bourderioux, Isabelle Sermet-Gaudelus, Virginie Rollet-Cohen, Sophie Guérin-Pfyffer, Ida Chiara Guerrera, Thao Nguyen-Khoa, Aleksander Edelman, Joanna Lipecka, Alain Schmitt, Myriam Mesbahi, Vincent Jung

Publikováno v: Journal of Proteomics
Journal of Proteomics, Elsevier, 2018, 185, ⟨10.1016/J.JPROT.2018.07.001⟩
Journal of Proteomics, 2018, 185, ⟨10.1016/J.JPROT.2018.07.001⟩

Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are pulmonary genetic disorders associated with inflammation and heterogeneous progression of the lung disease. We hypothesized that respiratory exosomes, nanovesicles circulating in the respi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6e3b0d929b05426b9ccb148654f31a
https://pubmed.ncbi.nlm.nih.gov/30032860

Sensitivity of mass spectrometry analysis depends on the shape of the filtration unit used for filter aided sample preparation (FASP)

Autor: Aleksander Edelman, Joanna Lipecka, Marie-Andrée Bessard, Ida Chiara Guerrera, Peter van Endert, Matthieu Bourderioux, Cerina Chhuon

Publikováno v: Proteomics. 16(13)

Efficient protein solubilization using detergents is required for in-depth proteome analysis, but successful LC-MS/MS analysis greatly depends on proper detergents removal. A commonly used sample processing method is the filter-aided sample preparati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362a08bbe28eff552cfc526b8c8556eb
https://pubmed.ncbi.nlm.nih.gov/27219663

Localized lipidomics in cystic fibrosis: TOF-SIMS imaging of lungs from Pseudomonas aeruginosa-infected mice

Autor: Claudia Bich, Alain Brunelle, Emilie L. Saussereau, Janine Fritsch, Aleksander Edelman, Nicolas Desbenoit, Mario Ollero, Matthieu Bourderioux

Publikováno v: International Journal of Biochemistry and Cell Biology
International Journal of Biochemistry and Cell Biology, Elsevier, 2014, 52, pp.77-82. ⟨10.1016/j.biocel.2014.01.026⟩
International Journal of Biochemistry and Cell Biology, Elsevier, 2014, 52, pp.77-82. 〈10.1016/j.biocel.2014.01.026〉

International audience; : A consistent body of research has linked cystic fibrosis (CF) with variations in the tissue and fluid content in a number of lipid molecules. However, little is known about the spatial localization of those variations. We ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d196fbc22f540ecba8ebf9f65cb71c0f
https://hal.archives-ouvertes.fr/hal-00995365